Items where Department is "Biomedical & Life Sciences" and Year is 2008

A

Allen, James W. A. and Ferguson, Stuart J. and Ginger, Michael L. (2008) Distinctive biochemistry in the trypanosome mitochondrial intermembrane space suggests a model for stepwise evolution of the MIA pathway for import of cysteine-rich proteins. FEBS Letters, 582 (19). pp. 2817-2825. ISSN 0014-5793

Allen, James W. A. and Jackson, Andrew P. and Rigden, Daniel J. and Willis, Antony C. and Ferguson, Stuart J. and Ginger, M. L. (2008) Order within a mosaic distribution of mitochondrial c-type cytochrome biogenesis systems? FEBS Journal, 275 (10). pp. 2385-2402. ISSN 1742-464X

Allsop, David and Mayes, Jennifer and Moore, Susan and Masad, Atef and Tabner, Brian J (2008) Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease. Biochemical Society Transactions, 36 (6). pp. 1293-1298. ISSN 1470-8752

Au, Catherine and Benedetto, Alexandre and Aschner, Michael (2008) Manganese transport in eukaryotes : the role of DMT1. NeuroToxicology, 29 (4). pp. 569-576. ISSN 0161-813X

Austen, Brian M and Paleologou, Katerina E and Ali, Sumaya A E and Qureshi, Mohamed M and Allsop, David and El-Agnaf, Omar M A (2008) Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's β-amyloid peptide. Biochemistry, 47 (7). pp. 1984-1992. ISSN 0006-2960

B

Bates, Paul A (2008) Leishmania sand fly interaction : progress and challenges. Current Opinion in Microbiology, 11 (4). pp. 340-344. ISSN 1369-5274

Bhella, David and Gatherer, Derek and Chaudhry, Yasmin and Pink, Rebecca and Goodfellow, Ian G. (2008) Structural insights into calicivirus attachment and uncoating. Journal of Virology, 82 (16). pp. 8051-8058. ISSN 0022-538X

Bowie, Andrew G. and Unterholzner, Leonie (2008) Viral evasion and subversion of pattern-recognition receptor signalling. Nature Immunology, 8 (12). pp. 911-922. ISSN 1529-2908

Bradley, Amanda J. and Kovács, Ida J. and Gatherer, Derek and Dargan, Derrick J. and Alkharsah, Khaled R. and Chan, Paul K. S. and Carman, William F. and Dedicoat, Martin and Emery, Vincent C. and Geddes, Colin C. and Gerna, Giuseppe and Ben-Ismaeil, Bassam and Kaye, Steve and McGregor, Alistair and Moss, Paul A. and Pusztai, Rozalia and Rawlinson, William D. and Scott, Gillian M. and Wilkinson, Gavin W. G. and Schulz, Thomas F. and Davison, Andrew J. (2008) Genotypic analysis of two hypervariable human cytomegalovirus genes. Journal of Medical Virology, 80 (9). pp. 1615-1623. ISSN 0146-6615

Broughton, Susan and Alic, Nazif and Slack, Cathy and Bass, Timothy and Ikeya, Tomoatsu and Vinti, Giovanna and Tommasi, Anna Maria and Driege, Yasmine and Hafen, Ernst and Partridge, Linda (2008) Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. PLoS ONE, 3 (11): e3721. ISSN 1932-6203

C

Clancy, D. J. (2008) Variation in mitochondrial genotype has substantial lifespan effects which may be modulated by nuclear background. Aging Cell, 7 (6). pp. 795-804. ISSN 1474-9726

Crossman, Arthur T. and Urbaniak, Michael D. and Ferguson, Michael A. J. (2008) Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) : a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis. Carbohydrate Research, 343 (9). pp. 1478-1481. ISSN 0008-6215

D

Dekaney, Christopher M. and von Allmen, Douglas C. and Garrison, Aaron P. and Rigby, Rachael J. and Lund, P. Kay and Henning, Susan J. and Helmrath, Michael A. (2008) Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection. Surgery, 144 (2). pp. 174-181. ISSN 0039-6060

Dillon, Mandy and Parry, Jacqueline (2008) Characterization of temperate cyanophages active against freshwater phycocyanin-rich Synechococcus species. Freshwater Biology, 53 (6). pp. 1253-1261. ISSN 0046-5070

Dillon, R. J. and Webster, G. and Weightman, A. J. and Dillon, V. M. and Blanford, S. and Charnley, A. K. (2008) Composition of Acridid gut bacterial communities as revealed by 16S rRNA gene analysis. Journal of Invertebrate Pathology, 97 (3). pp. 265-272. ISSN 0022-2011

Dobreva, Iveta and Fielding, Andrew and Foster, Leonard J. and Dedhar, Shoukat (2008) Mapping the integrin-linked kinase interactome using SILAC. Journal of Proteome Research, 7 (4). pp. 1740-1749. ISSN 1535-3893

Dublon, I. A.N. and Hamilton, J. G.C. and Kirk, W. D.J. (2008) Quantification of the release rate of the aggregation pheromone of the western flower thrips, Frankliniella occidentalis (Pergande), using solid-phase microextraction (SPME). Acta Phytopathologica et Entomologica Hungarica, 43 (2). pp. 249-256. ISSN 0238-1249

Duggan, James and Jamal, Ghadir and Tilley, Mark and Davis, Ben and McKenzie, Graeme and Vere, Kelly and Somekh, Michael G. and O'Shea, Paul and Harris, Helen (2008) Functional imaging of microdomains in cell membranes. European Biophysics Journal, 37 (8). pp. 1279-1289. ISSN 0175-7571

F

Fielding, Andrew B. and Dobreva, Iveta and Dedhar, Shoukat (2008) Beyond focal adhesions : integrin-linked kinase associates with tubulin and regulates mitotic spindle organization. Cell Cycle, 7 (13). pp. 1899-1906. ISSN 1538-4101

Fielding, Andrew B. and Dobreva, Iveta and McDonald, Paul C and Foster, Leonard J and Dedhar, Shoukat (2008) Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization. Journal of Cell Biology, 180 (4). pp. 681-9. ISSN 0021-9525

Foulds, Penelope and McAuley, Erica and Gibbons, Linda and Davidson, Yvonne and Pickering-Brown, Stuart M and Neary, David and Snowden, Julie S and Allsop, David and Mann, David M A (2008) TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration. Acta Neuropathologica, 116 (2). pp. 141-146. ISSN 0001-6322

Fullwood, Nigel J. (2008) Microscopy for life scientists. Science, 321 (5895). p. 1445. ISSN 0036-8075

G

Gatherer, Derek (2008) Finite Universe of Discourse : The Systems Biology of Walter Elsasser (1904-1991). The Open Biology Journal, 1. pp. 9-20. ISSN 1874-1967

Ginger, Michael L. and Portman, Neil and McKean, Paul G. (2008) Swimming with protists : perception, motility and flagellum assembly. Nature Reviews in Microbiology, 6 (11). pp. 838-850. ISSN 1740-1534

Guerin, K. and Gregory-Evans, C. Y. and Hodges, Matt and Moosajee, M. and Mackay, D. S. and Gregory-Evans, K. and Flannery, John G. (2008) Systemic aminoglycoside treatment in rodent models of retinitis pigmentosa. Experimental Eye Research, 87 (3). pp. 197-207. ISSN 1096-0007

H

Hamilton, J. G.C. (2008) Sandfly pheromones : Their biology and potential for use in control programs. Parasite, 15 (3). pp. 252-256. ISSN 1252-607X

Harrison, Linda M. and Morris, James A. and Lauder, Robert M. and Telford, David R. (2008) The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. FEMS Immunology and Medical Microbiology, 54 (1). pp. 137-143. ISSN 1574-695X

Hawkes, Cheryl A. and McLaurin, Jo Anne (2008) Clinical immunotherapy trials in Alzheimer's disease. Drug Discovery Today: Therapeutic Strategies, 5 (3). pp. 177-183. ISSN 1740-6773

Hodges, Matt and Gregory-Evans, Cheryl Y. and Gregory-Evans, Kevin (2008) A clearer view of stem cells in retinal disease. In: Stem cell repair and regeneration :. Imperial College Press, London, pp. 227-245. ISBN 978-1-86094-980-7

Huckerby, Thomas and Lauder, R. M. (2008) NMR analysis of chondroitin sulphates. ACS Polymer Preprints, 49 (1). pp. 702-703.

Huckerby, Thomas N. and Lauder, Robert M. (2008) POLY 73-NMR analysis of chondroitin sulphates. Abstracts of Papers of the American Chemical Society, 235. -. ISSN 0065-7727

J

Jayawardane, Gamini and Russell, George C. and Thomson, Jackie and Deane, David and Cox, Helen and Gatherer, Derek and Ackermann, Mathias and Haig, David M. and Stewart, James P. (2008) A captured viral interleukin 10 gene with cellular exon structure. Journal of General Virology, 89 (10). pp. 2447-2455. ISSN 0022-1317

Jones, C J P and Harris, L K and Whittingham, J and Aplin, J D and Mayhew, T M (2008) A re-appraisal of the morphophenotype and basal lamina coverage of cytotrophoblasts in human term placenta. Placenta, 29 (2). pp. 215-219. ISSN 0143-4004

K

Klasson, Lisa and Walker, Thomas and Sebaihia, Mohammed and Sanders, Mandy J. and Quail, Michael A. and Lord, Angela and Sanders, Susanne and Earl, Julie and O'Neill, Scott L. and Thomson, Nicholas and Sinkins, Steven P. and Parkhill, Julian (2008) Genome evolution of Wolbachia strain wPip from the Culex pipiens group. Molecular Biology and Evolution, 25 (9). pp. 1877-1887. ISSN 0737-4038

L

Lauder, Robert (2008) Practical Skills. Pearson, London. ISBN 978-1-84658-777-1

Leung, Maxwell C. K. and Williams, Phillip L. and Benedetto, Alexandre and Au, Catherine and Helmcke, Kirsten J. and Aschner, Michael and Meyer, Joel N. (2008) Caenorhabditis elegans : an emerging model in biomedical and environmental toxicology. Toxicological sciences : an official journal of the Society of Toxicology, 106 (1). pp. 5-28. ISSN 1096-0929

Long, Shaojun and Jirku, Milan and Mach, Jan and Ginger, Michael L. and Sutak, Robert and Richardson, Des and Tachezy, Jan and Lukes, Julius (2008) Ancestral roles of eukaryotic frataxin: mitochondrial frataxin function and heterologous expression of hydrogenosomal Trichomonas homologs in trypanosomes. Molecular Microbiology, 69 (1). pp. 94-109. ISSN 0950-382X

Lund, P. Kay and Rigby, Rachael J. (2008) What Are the Mechanisms of Fibrosis in IBD? Inflammatory Bowel Diseases, 14 (Supple). S127-S128. ISSN 1078-0998

M

Maingon, Rhayza D.C. and Ward, Richard D. and Hamilton, James G.C. and Bauzer, Luiz G.S.R. and Peixoto, Alexandre A. (2008) The Lutzomyia longipalpis species complex : does population sub-structure matter to Leishmania transmission? Trends in Parasitology, 24 (1). pp. 12-17. ISSN 1471-4922

Mamali, I. and Kotsantis, P. and Lampropoulou, M. and Marmaras, V.J. (2008) Elk-1 associates with FAK, regulates the expression of FAK and MAP kinases as well as apoptosis in HK-2 cells. Journal of Cellular Physiology, 216 (1). pp. 198-206.

McCaughan, Danny and Au, Catherine and Benedetto, Alexandre and Milatovic, Dejan and Aschner, Judy and Aschner, Michael (2008) Antioxidant properties of blirubin in the model organism, Caenorhabditis elegans. International Journal of Neuroprotection and Neuroregeneration, 4 (3). pp. 252-262. ISSN 1745-1183

McDonald, Paul C. and Fielding, Andrew B. and Dedhar, Shoukat (2008) Integrin-linked kinase--essential roles in physiology and cancer biology. Journal of Cell Science, 121 (19). pp. 3121-3132. ISSN 0021-9533

McGeoch, Duncan J. and Davison, Andrew J. and Dolan, Aidan and Gatherer, Derek and Sevilla-Reyes, Edgar E. (2008) Molecular Evolution of the Herpesvirales. In: Origin and Evolution of Viruses :. Elsevier Ltd, pp. 447-475. ISBN 9780123741530

McMillan, T. J. and Leatherman, E. and Ridley, A. J. and Shorrocks, J. and Tobi, S. E. and Whiteside, J. R. (2008) Cellular effects of long wavelength UV light (UVA) on mammalian cells. Journal of Pharmacy and Pharmacology, 60 (8). pp. 969-976. ISSN 0022-3573

Montagnes, David and Barbosa, Ana and Boenigk, Jens and Davidson, Keith and Jurgens, Klaus and Macek, Miroslav and Parry, Jacqueline and Roberts, Emily and Simek, Karl (2008) Selective feeding behaviour of key free-living protists : avenues for continued study. Aquatic Microbial Ecology, 53. pp. 83-98. ISSN 0948-3055

Moran, Gordon W. and Leslie, Fiona C. and Levison, Scott E. and Worthington, J and McLaughlin, John T. (2008) Enteroendocrine cells : neglected players in gastrointestinal disorders? Therapeutic Advances in Gastroenterology, 1 (1). pp. 51-60. ISSN 1756-283X

N

Nakamura, Takahiro and Ohtsuka, Toshiyuki and Sekiyama, Eiichi and Cooper, Leanne J. and Kokubu, Hiroshi and Fullwood, Nigel J. and Barrandon, Yann and Kageyama, Ryoichiro and Kinoshita, Shigeru (2008) Hes1 regulates corneal development and the function of corneal epithelial stem/progenitor cells. Stem Cells, 26 (5). pp. 1265-1274. ISSN 1066-5099

Nakamura, Takahiro and Sekiyama, Eiichi and Takaoka, Maho and Bentley, Adam James and Yokoi, Norihiko and Fullwood, Nigel J. and Kinoshita, Shigeru (2008) The use of trehalose-treated freeze-dried amniotic membrane for ocular surface reconstruction. Biomaterials, 29 (27). pp. 3729-3737. ISSN 0142-9612

O

Owen-Lynch, Penelope Jane (2008) Analyzing the oscillatory components of the dynamics of blood flow. Journal of Applied Physiology, 105 (1). 374; author reply 389. ISSN 8750-7587

P

Parkin, Edward (2008) Alpha-Secretase and Alzheimer's disease. In: Recent advances in the biology of secretases, key proteases in Alzheimer's disease :. Research Signpost, pp. 183-211. ISBN 978-81-308-0263-3

Parsons, Jason L. and Tait, Philip S. and Finch, David and Dianova, Irina I. and Allinson, Sarah L. and Dianov, Grigory L. (2008) CHIP-Mediated Degradation and DNA Damage-Dependent Stabilization Regulate Base Excision Repair Proteins. Molecular Cell, 29 (4). pp. 477-487. ISSN 1097-2765

Q

Quincozes-Santos, André and Abib, Renata Torres and Leite, Marina Concli and Bobermin, Daiane and Bambini-Junior, Victorio and Gonçalves, Carlos-Alberto and Riesgo, Rudimar and Gottfried, Carmem (2008) Effect of the atypical neuroleptic risperidone on morphology and S100B secretion in C6 astroglial lineage cells. Molecular and Cellular Biochemistry, 314 (1-2): 59. pp. 59-63. ISSN 0300-8177

R

Ranasinghe, Shalindra and Rogers, Matthew E and Hamilton, James G C and Bates, Paul A and Maingon, Rhayza D C (2008) A real-time PCR assay to estimate Leishmania chagasi load in its natural sand fly vector Lutzomyia longipalpis. Transactions of The Royal Society of Tropical Medicine and Hygiene, 102 (9). pp. 875-882. ISSN 0035-9203

Robinson, S. J. and Sünram-Lea, S. I. and Leach, J. and Owen-Lynch, P. J. (2008) The effects of exposure to an acute naturalistic stressor on working memory, state anxiety and salivary cortisol concentrations. Stress, 11 (2). pp. 115-124. ISSN 1025-3890

Rogers, Matthew E and Hajmová, Martina and Joshi, Manju B and Sadlova, Jovana and Dwyer, Dennis M and Volf, Petr and Bates, Paul A (2008) Leishmania chitinase facilitates colonization of sand fly vectors and enhances transmission to mice. Cellular Microbiology, 10 (6). pp. 1363-72. ISSN 1462-5822

S

Sant'Anna, Mauricio R and Alexander, Bruce and Bates, Paul A and Dillon, Rod J (2008) Gene silencing in phlebotomine sand flies : Xanthine dehydrogenase knock down by dsRNA microinjections. Insect Biochemistry and Molecular Biology, 38 (6). pp. 652-660. ISSN 0965-1748

Sant'Anna, Mauricio R V and Jones, Nathaniel G and Hindley, Jonathan A and Mendes-Sousa, Antonio F and Dillon, Rod J and Cavalcante, Reginaldo R and Alexander, Bruce and Bates, Paul A (2008) Blood meal identification and parasite detection in laboratory-fed and field-captured Lutzomyia longipalpis by PCR using FTA databasing paper. Acta Tropica, 107 (3). pp. 230-237.

Saunders, R. D. C. and Boubriak, I. and Clancy, D. J. and Cox, L. S. (2008) Identification and characterization of a Drosophila ortholog of WRN exonuclease that is required to maintain genome integrity. Aging Cell, 7 (3). pp. 418-425. ISSN 1474-9726

Sun, Yedi and Zhang, Guohua and Hawkes, Cheryl A. and Shaw, James E. and McLaurin, Jo Anne and Nitz, Mark (2008) Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation. Bioorganic and Medicinal Chemistry, 16 (15). pp. 7177-7184. ISSN 0968-0896

T

Takaoka, Maho and Nakamura, Takahiro and Sugai, Hajime and Bentley, Adam James and Nakajima, Naoki and Fullwood, Nigel J. and Yokoi, Norihiko and Hyon, Suong-Hyu and Kinoshita, Shigeru (2008) Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive. Biomaterials, 29 (19). pp. 2923-2931. ISSN 0142-9612

U

Unterholzner, Leonie and Bowie, Andrew G. (2008) The interplay between viruses and innate immune signaling : recent insights and therapeutic opportunities. Biochemical Pharmacology, 75 (3). pp. 589-602. ISSN 0006-2952

Urbaniak, Michael D. and Crossman, Arthur and Ferguson, Michael A. J. (2008) Probing Trypanosoma brucei glycosylphosphatidylinositol biosynthesis using novel precursor-analogues. Chemical Biology and Drug Design, 72 (2). pp. 127-132. ISSN 1747-0277

Urbaniak, Michael D. and Yashunsky, Dmitry V. and Crossman, Arthur and Nikolaev, Andrei V. and Ferguson, Michael A. J. (2008) Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues. ACS Chemical Biology, 3 (10). pp. 625-634. ISSN 1554-8929

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Walsh, Michael J. and Fellous, Tariq G. and Hammiche, Azzedine and Lin, Wey-Ran and Fullwood, Nigel J. and Grude, Olaug and Bahrami, Fariba and Nicholson, James M. and Cotte, Marine and Susini, Jean and Pollock, Hubert M. and Brittan, Mairi and Martin-Hirsch, Pierre L. and Alison, Malcolm R. and Martin, Francis L. (2008) FTIR micro-spectroscopy identifies symmetric PO2- modifications as a marker of the putative stem cell region of human intestinal crypts. Stem Cells, 26 (10). pp. 108-118. ISSN 1066-5099

Walsh, Michael J. and Singh, Maneesh N. and Stringfellow, Helen F. and Pollock, Hubert M. and Hammiche, Azzedine and Grude, Olaug and Fullwood, Nigel J. and Pitt, Mark A. and Martin-Hirsch, Pierre L. and Martin, Francis L. (2008) FTIR Microspectroscopy Coupled with Two-Class Discrimination Segregates Markers Responsible for Inter- and Intra-Category Variance in Exfoliative Cervical Cytology. Biomarker Insights, 3. pp. 179-189. ISSN 1177-2719

Wilkinson, D Katie and Turner, E Jane and Parkin, Edward T and Garner, Ashley E and Harrison, Penny J and Crawford, Mark and Stewart, Gordon W and Hooper, Nigel M (2008) Membrane raft actin deficiency and altered Ca2+-induced vesiculation in stomatin-deficient overhydrated hereditary stomatocytosis. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1778 (1). pp. 125-132. ISSN 0005-2736

Wright, Daniel and Munro, Ewen and Corbett, Mark and Bentley, Adam James and Fullwood, Nigel J. and Murray, Stephen and Price, Clive (2008) The Saccharomyces cerevisiae actin cytoskeletal component Bsp1p has an auxiliary role in actomyosin ring function and in the maintenance of bud-neck structure. Genetics, 178 (4). pp. 1903-1914. ISSN 0016-6731

Wright, K. L. and Duncan, M. and Sharkey, K. A. (2008) Cannabinoid CB2 receptors in the gastrointestinal tract : a regulatory system in states of inflammation. British Journal of Pharmacology, 153 (2). pp. 263-270. ISSN 1476-5381

Wright, Karen L. and Robertson, Duncan A. F. and Moyer, Mary P. and Ward, Stephen G. (2008) Long term cannabinoid receptor (CB1) blockade in obesity : implications for the development of colorectal cancer. International Journal of Cancer, 122 (8). pp. 1920-1921. ISSN 0020-7136

Z

Zhao, Bojun and Allinson, Sarah L. and Ma, Aihua and Bentley, Adam J. and Martin, Francis L. and Fullwood, Nigel J. (2008) Targeted cornea limbal stem/progenitor cell transfection in an organ culture model. Investigative Ophthalmology and Visual Science, 49 (8). pp. 3395-3401. ISSN 0146-0404