Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) : a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis

Crossman, Arthur T. and Urbaniak, Michael D. and Ferguson, Michael A. J. (2008) Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) : a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis. Carbohydrate Research, 343 (9). pp. 1478-1481. ISSN 0008-6215

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Abstract

1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) was prepared to probe the reaction mechanism of the putative zinc-dependent metalloenzyme 2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1-->6)-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis.

Item Type:

Journal Article

Journal or Publication Title:

Carbohydrate Research

Uncontrolled Keywords:

/dk/atira/pure/subjectarea/asjc/1300/1303

Subjects:

?? enzyme inhibitorsglucosamineglycosylphosphatidylinositolshydroxyureainositol phosphatesmetalloproteinsmolecular structurebiochemistryorganic chemistryanalytical chemistry ??

Departments:

Faculty of Health and Medicine > Biomedical & Life Sciences

ID Code:

66394

Deposited By:

ep_importer_pure

Deposited On:

17 Sep 2013 08:08

Refereed?:

Yes

Published?:

Published

Last Modified:

15 Jul 2024 14:12

URI:

https://eprints.lancs.ac.uk/id/eprint/66394