The Lutzomyia longipalpis species complex:does population sub-structure matter to Leishmania transmission?

Maingon, Rhayza D.C. and Ward, Richard D. and Hamilton, James G.C. and Bauzer, Luiz G.S.R. and Peixoto, Alexandre A. (2008) The Lutzomyia longipalpis species complex:does population sub-structure matter to Leishmania transmission? Trends in Parasitology, 24 (1). pp. 12-17. ISSN 1471-4922

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Abstract

Leishmania chagasi causes visceral leishmaniasis and, to a lesser extent, atypical cutaneous leishmaniasis in Central and South America. Its main sand fly vector, Lutzomyia longipalpis s.l. (Diptera: Psychodidae) displays a complex population structure that might contribute to the observed clinical pleomorphism and to recent major urban epidemics. This article summarises our understanding on reproductive barriers and hybridisation among this vector's sibling incipient species. Identifying genes important for sand fly ecological adaptability and sand fly-Leishmania genetic co-variation could be helpful for interrupting Leishmania transmission.

Item Type: Journal Article
Journal or Publication Title: Trends in Parasitology
Uncontrolled Keywords: /dk/atira/pure/subjectarea/asjc/2700/2725
Subjects:
Departments: Faculty of Health and Medicine > Biomedical & Life Sciences
ID Code: 137184
Deposited By: ep_importer_pure
Deposited On: 30 Sep 2019 22:19
Refereed?: Yes
Published?: Published
Last Modified: 11 Feb 2020 05:36
URI: https://eprints.lancs.ac.uk/id/eprint/137184

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