Items where Department is "Biomedical & Life Sciences" and Year is 2009

Alcendor, Donald J and Zong, Jianchao and Dolan, Aidan and Gatherer, Derek and Davison, Andrew J. and Hayward, Gary S. (2009) Patterns of divergence in the vCXCL and vGPCR gene clusters in primate cytomegalovirus genomes. Virology, 395 (1). pp. 21-32. ISSN 0042-6822

Allen, James W. A. and Sawyer, Elizabeth B. and Ginger, Michael L. and Barker, Paul D. and Ferguson, Stuart J. (2009) Variant c-type cytochromes as probes of the substrate specificity of the E. coli cytochrome c maturation (Ccm) apparatus. Biochemical Journal, 419. pp. 177-184. ISSN 0264-6021

Amritraj, A. and Hawkes, C. and Phinney, A. L. and Mount, H. T. and Scott, C. D. and Westaway, D. and Kar, S. (2009) Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains. Neurobiology of Aging, 30 (1). pp. 54-70. ISSN 0197-4580

Andre, Jane and Charnock, John and Sturzenbaum, Stephen R. and Kille, Peter and Morgan, A. John and Hodson, Mark E. (2009) Accumulated metal speciation in field populations of earthworms with multi-generational exposure to metalliferous soils : cell fractionation and high energy synchrotron analyses. Environmental Science and Technology, 43 (17). pp. 6822-6829. ISSN 0013-936X

Araki, Alejandra S. and Vigoder, Felipe M. and Bauzer, Luiz G.S.R. and Ferreira, Gabriel E.M. and Souza, Nataly A. and Araújo, Izeneide B. and Hamilton, James G.C. and Brazil, Reginaldo P. and Peixoto, Alexandre A. (2009) Molecular and behavioral differentiation among Brazilian populations of Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae). PLoS Neglected Tropical Diseases, 3 (1): e365. ISSN 1935-2727

Au, Catherine and Benedetto, Alexandre and Anderson, Joel and Labrousse, Arnaud and Erikson, Keith and Ewbank, Jonathan J. and Aschner, Michael (2009) SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans. PLoS ONE, 4 (11): e7792. ISSN 1932-6203

Benedetto, Alexandre and Au, Catherine and Aschner, Michael (2009) Manganese-induced dopaminergic neurodegeneration : insights into mechanisms and genetics shared with Parkinson's disease. Chemical Reviews, 109 (10). pp. 4862-4884. ISSN 0009-2665

Bland, Nicholas D. and Robinson, Philip and Thomas, Josie E. and Shirras, Alan D. and Turner, Anthony J. and Isaac, R. Elwyn (2009) Locomotor and geotactic behavior of Drosophila melanogaster over-expressing neprilysin 2. Peptides, 30 (3). pp. 571-574. ISSN 0196-9781

Boubriak, Ivan and Clancy, David J. and Borer, Christine and Saunders, Robert D. C. and Cox, Lynne S. (2009) Genome instability in Drosophila mutant for WRN-like exonuclease. Mutagenesis, 24 (1). pp. 106-107. ISSN 0267-8357

Boubriak, Ivan and Mason, Penelope A. and Clancy, David J. and Dockray, Joel and Saunders, Robert D. C. and Cox, Lynne S. (2009) DmWRNexo is a 3'aEuro"5' exonuclease : phenotypic and biochemical characterization of mutants of the Drosophila orthologue of human WRN exonuclease. Biogerontology, 10 (3). pp. 267-277. ISSN 1389-5729

Bradley, Amanda J. and Lurain, Nell S. and Ghazal, Peter and Trivedi, Urmi and Cunningham, Charles and Baluchova, Katarina and Gatherer, Derek and Wilkinson, Gavin W. G. and Dargan, Derrick J. and Davison, Andrew J. (2009) High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169. Journal of General Virology, 90 (10). pp. 2375-2380. ISSN 0022-1317

Brandão-Filho, Sinval P. and Balbino, Valdir Q. and Marcondes, Carlos B. and Brazil, Reginaldo P. and Hamilton, James G. and Shaw, Jeffrey J. (2009) Should reproductively isolated populations of Lutzomyia longipalpis sensu lato receive taxonomically valid names? Memorias do Instituto Oswaldo Cruz, 104 (8). pp. 1197-1200. ISSN 0074-0276

Bray, D. P. and Bandi, K. K. and Brazil, R. P. and Oliveira, A. G. and Hamilton, J. G.C. (2009) Synthetic sex pheromone attracts the leishmaniasis vector Lutzomyia longipalpis (Diptera: Psychodidae) to traps in the field. Journal of Medical Entomology, 46 (3). pp. 428-434. ISSN 0022-2585

Brazil, Reginaldo P. and Caballero, Norath Natalia and Hamilton, James Gordon C. (2009) Identification of the sex pheromone of Lutzomyia longipalpis (Lutz & Neiva, 1912) (Diptera: Psychodidae) from Asunción, Paraguay. Parasites and Vectors, 2 (1): 51. ISSN 1756-3305

Broughton, Susan and Partridge, Linda (2009) Insulin/IGF-like signalling, the central nervous system and aging. Biochemical Journal, 418 (1). pp. 1-12. ISSN 0264-6021

Cains, Sarah and Shepherd, Andrew and Nabiuni, Mohammad and Owen-Lynch, Penelope Jane and Miyan, Jaleel (2009) Addressing a folate imbalance in fetal cerebrospinal fluid can decrease the incidence of congenital hydrocephalus. Journal of Neuropathology and Experimental Neurology, 68 (4). pp. 404-16. ISSN 0022-3069

Dawson, Neil and Ferrington, Linda and Olverman, Henry and Harmar, Anthony and Kelly, Paul (2009) Sex influences the effect of a lifelong increase in serotonin transporter function on cerebral metabolism. Journal of Neuroscience Research, 87 (10). pp. 2375-2385. ISSN 0360-4012

Dillon, Mandy and Parry, Jacqueline (2009) Amoebic grazing of freshwater Synechococcus strains rich in phycocyanin. FEMS Microbiology Ecology, 69 (1). pp. 106-112. ISSN 0168-6496

Fielding, Andrew B. and Dedhar, Shoukat (2009) The mitotic functions of integrin-linked kinase. Cancer Metastasis Reviews, 28 (1-2). pp. 99-111. ISSN 0167-7659

Foulds, Penny and Davidson, Yvonne and Mishra, Manjari and Hobson, David J and Humphreys, Kirsty M and Taylor, Mark and Johnson, Nancy and Weintraub, Sandra and Akiyama, Haruhiko and Arai, Tetsuaki and Hasegawa, Masato and Bigio, Eileen H and Benson, Fiona E and Allsop, David and Mann, David M A (2009) Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration. Acta Neuropathologica, 118 (5). pp. 647-658. ISSN 0001-6322

Fülöp, Vilmos and Sam, Katharine A. and Ferguson, Stuart J. and Ginger, Michael L. and Allen, James W. A. (2009) Structure of a trypanosomatid mitochondrial cytochrome c with heme attached via only one thioether bond and implications for the substrate recognition requirements of heme lyase. FEBS Journal, 276 (10). pp. 2822-2832. ISSN 1742-464X

Gadd, Morgan Stuart and Langley, David B and Guss, J Mitchell and Matthews, Jacqueline M (2009) Crystallization and diffraction of an Lhx4–Isl2 complex. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 65 (2). pp. 151-153. ISSN 1744-3091

Gatherer, Derek (2009) The 2009 H1N1 influenza outbreak in its historical context. Journal of Clinical Virology, 45 (3). pp. 174-178. ISSN 1386-6532

Gatherer, Derek (2009) On the origin of influenza A hemagglutinin. Indian Journal of Microbiology, 49 (4). pp. 352-357. ISSN 0046-8991

Gregory-Evans, Kevin and Chang, Francis and Hodges, Matt and Gregory-Evans, Cheryl Y. (2009) Ex vivo gene therapy using intravitreal injection of GDNF-secreting mouse embryonic stem cells in a rat model of retinal degeneration. Molecular Vision, 15. pp. 962-973. ISSN 1090-0535

Grude, Olaug and Nakamura, Takahiro and Hammiche, Azzedine and Bentley, Adam J. and Martin, Francis L. and Pollock, Hubert M. and Kinoshita, Shigeru and Fullwood, Nigel J. (2009) Discrimination of human stem cells by photothermal microspectroscopy. Vibrational Spectroscopy, 49 (1). pp. 22-27. ISSN 0924-2031

Hamilton, Alison and Hölscher, Christian (2009) Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system. NeuroReport, 20 (13). pp. 1161-1166. ISSN 0959-4965

Harris, Benjamin and Pereira, Isabel and Parkin, Edward (2009) Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein. Brain Research, 1296 (n/a). pp. 203-215.

Harrison, L. M and Morris, J. A. and Lauder, R. M. and Telford, D. R. (2009) Staphylococcal pyrogenic toxins in infant urine samples: a possible marker of transient bacteraemia. Journal of Clinical Pathology, 62 (8). pp. 735-738. ISSN 1472-4146

Hart, Sarah R. and Wai Lau, King Wai and Hao, Zhiqi and Broadhead, Richard and Portman, Neil and Huhmer, Andreas and Gull, Keith and McKean, Paul G. and Hubbard, Simon J. and Gaskell, Simon J. (2009) Analysis of the trypanosome flagellar proteome using a combined electron transfer collisionally activated dissociation strategy. Journal of The American Society for Mass Spectrometry, 20 (2). pp. 167-175. ISSN 1044-0305

Hawkes, Cheryl A. and McLaurin, Joanne (2009) Selective targeting of perivascular macrophages for clearance of β-amyloid in cerebral amyloid angiopathy. Proceedings of the National Academy of Sciences of the United States of America, 106 (4). pp. 1261-1266. ISSN 0027-8424

Hawkes, Cheryl A. and Ng, Vivian and McLaurin, Joanne (2009) Small molecule inhibitors of Aβ-aggregation and neurotoxicity. Drug Development Research, 70 (2). pp. 111-124. ISSN 0272-4391

Hopkins, Sally and Carter, Steven R. and Haycock, John W. and Fullwood, Nigel J. and MacNeil, Sheila and Rimmer, Stephen (2009) Sub-micron poly(N-isopropylacrylamide) particles as temperature responsive vehicles for the detachment and delivery of human cells. Soft Matter, 5 (24). pp. 4928-4937. ISSN 1744-683X

Ikeya, Tomoatsu and Broughton, Susan and Alic, Nazif and Grandison, Richard and Partridge, Linda (2009) The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila. Proceedings of the Royal Society B: Biological Sciences, 276 (1674). pp. 3799-3807. ISSN 0962-8452

Isaac, Elwyn and Carhan, Ahmet and Tang, Ke and Shirras, Christine and Shirras, Alan (2009) Increased fragmentation of night-time sleep in Drosophila melanogaster lacking the angiotensin-converting enzyme-related (ACER) peptidase. Journal of Neurogenetics, 23 (Supple). S70-S70. ISSN 0167-7063

Isaac, R. Elwyn and Bland, Nicholas D. and Shirras, Alan D. (2009) Neuropeptidases and the metabolic inactivation of insect neuropeptides. General and Comparative Endocrinology, 162 (1). pp. 8-17. ISSN 0016-6480

Johnson, Andrew C. and Acreman, Mike C. and Dunbar, Michael J. and Feist, Stephen W. and Giacomello, Anna Maria and Gozlan, Rodolph E. and Hinsley, Shelley A. and Ibbotson, Anton T. and Jarvie, Helen P. and Jones, J. Iwan and Longshaw, Matt and Maberly, Stephen C. and Marsh, Terry J. and Neal, Colin and Newman, Jonathan R. and Nunn, Miles A. and Pickup, Roger W. and Reynard, Nick S. and Sullivan, Caroline A. and Sumpter, John P. and Williams, Richard J. (2009) The British river of the future : How climate change and human activity might affect two contrasting river ecosystems in England. Science of the Total Environment, 407 (17). pp. 4787-4798. ISSN 0048-9697

Kambris, Zakaria and Cook, Peter E. and Phuc, Hoang K. and Sinkins, Steven P. (2009) Immune activation by life-shortening Wolbachia and reduced filarial competence in mosquitoes. Science, 326 (5949). pp. 134-136. ISSN 0036-8075

Kasai, Takashi and Tokuda, Takahiko and Ishigami, Noriko and Sasayama, Hiroshi and Foulds, Penelope and Mitchell, Douglas J and Mann, David M A and Allsop, David and Nakagawa, Masanori (2009) Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathologica, 117 (1). pp. 55-62. ISSN 0001-6322

Lauder, Robert M. (2009) Chondroitin sulphate : a complex molecule with potential impacts on a wide range of biological systems. Complementary Therapies in Medicine, 17 (1). pp. 56-62.

Leendertz, Fabian H. and Deckers, Merlin and Schempp, Werner and Lankester, Felix and Boesch, Christophe and Mugisha, Lawrence and Dolan, Aidan and Gatherer, Derek and McGeoch, Duncan J. and Ehlers, Bernhard (2009) Novel cytomegaloviruses in free-ranging and captive great apes : phylogenetic evidence for bidirectional horizontal transmission. Journal of General Virology, 90 (10). pp. 2386-2394. ISSN 0022-1317

Lewis, J. W. and Morley, N.J. and Drinkall, Janice and Jamieson, B. J. and Wright, R. and Parry, Jacqueline (2009) The toxic effect of Streptomyces griseus spores and exudates on gill pathology of freshwater fish. Ecotoxicology and Environmental Safety, 72 (1). pp. 173-181. ISSN 0147-6513

Matharu, Balpreet and Gibson, Gillian and Parsons, Richard and Huckerby, Thomas N and Moore, Susan A and Cooper, Leanne J and Millichamp, Robert and Allsop, David and Austen, Brian (2009) Galantamine inhibits β-amyloid aggregation and cytotoxicity. Journal of the Neurological Sciences, 280 (1-2). pp. 49-58.

Morris, James A. and Harrison, Linda and Brodison, Adrian and Lauder, Robert (2009) Sudden infant death syndrome and cardiac arrhythmias. Future Cardiology, 5 (2). pp. 201-207. ISSN 1744-8298

Mort, Richard L. (2009) Quantitative analysis of patch patterns in mosaic tissues with ClonalTools software. Journal of Anatomy, 215 (6). pp. 698-704. ISSN 0021-8782

Mort, Richard L. and Ramaesh, Thaya and Kleinjan, Dirk A. and Morley, Steven D. and West, John D. (2009) Mosaic analysis of stem cell function and wound healing in the mouse corneal epithelium. Developmental Biology, 9: 4. ISSN 0012-1606

Olego-Fernandez, Sofia and Vaughan, Sue and Shaw, Michael K. and Gull, Keith and Ginger, Michael L. (2009) Cell morphogenesis of Trypanosoma brucei requires the paralogous, differentially expressed calpain-related proteins CAP5.5 and CAP5.5V. Protist, 160 (4). pp. 576-590. ISSN 1434-4610

Paleologou, Katerina E and Kragh, Christine L and Mann, David M A and Salem, Sultan A and Al-Shami, Rania and Allsop, David and Hassan, Ahmed H and Jensen, Poul H and El-Agnaf, Omar M A (2009) Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies. Brain, 132 (4). pp. 1093-1101. ISSN 1460-2156

Papachristou, E. and Papadimitropoulos, A. and Kotsantis, P. and Goumenos, D.S. and Katsoris, P.G. and Vlachojannis, J.G. (2009) Cyclosporine induces endothelin-1 mRNA synthesis and nitric oxide production in human proximal tubular epithelial cell cultures. Renal Failure, 31 (5). pp. 372-376.

Parkin, Edward and Harris, Benjamin (2009) A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10. Journal of Neurochemistry, 108 (6). pp. 1464-1479. ISSN 1471-4159

Plytycz, Barbara and Lis-Molenda, Urszula and Cygal, Malgorzata and Kielbasa, Edyta and Grebosz, Anna and Duchnowski, Michał and Andre, Jane and Morgan, A. John (2009) Riboflavin content of coelomocytes in earthworm (Dendrodrilus rubidus) field populations as a molecular biomarker of soil metal pollution. Environmental Pollution, 157 (11). pp. 3042-3050. ISSN 0269-7491

Portman, Neil and Lacomble, Sylvain and Thomas, Benjamin and McKean, Paul G. and Gull, Keith (2009) Combining RNA interference mutants and comparative proteomics to identify protein component interactions and dependencies in a eukaryotic flagellum. Journal of Biological Chemistry, 284 (9). pp. 5610-5619. ISSN 1083-351X

Ridley, Andrew J. and Whiteside, James R. and McMillan, Trevor J. and Allinson, Sarah L. (2009) Cellular and sub-cellular responses to UVA in relation to carcinogenesis. International Journal of Radiation Biology, 85 (3). pp. 177-195. ISSN 0955-3002

Rigby, R. J. and Hunt, M. R. and Scull, B. P. and Simmons, J. G. and Speck, K. E. and Helmrath, M. A. and Lund, P. K. (2009) A new animal model of postsurgical bowel inflammation and fibrosis : the effect of commensal microflora. Gut, 58 (8). pp. 1104-1112. ISSN 0017-5749

Rigden, D. J. and Michels, P. A. M. and Ginger, Michael L. (2009) Autophagy in protists : examples of secondary loss, lineage-specific innovations, and the conundrum of re-modelling a single mitochondrion. Autophagy, 5 (6). pp. 784-794. ISSN 1554-8627

Rogers, Matthew and Kropf, Pascale and Choi, Beak-San and Dillon, Rod and Podinovskaia, Maria and Bates, Paul and Müller, Ingrid (2009) Proteophosophoglycans regurgitated by Leishmania-infected sand flies target the L-arginine metabolism of host macrophages to promote parasite survival. PLoS Pathogens, 5 (8): e1000555. ISSN 1553-7374

Rudd, Timothy R and Skidmore, Mark A and Guimond, Scott E and Cosentino, Cesare and Torri, Giangiacomo and Fernig, David G and Lauder, Robert M and Guerrini, Marco and Yates, Edwin A (2009) Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra. Glycobiology, 19 (1). pp. 52-67. ISSN 1460-2423

Rudd, Timothy R. and Skidmore, Mark A. and Guimond, Scott E. and Holman, Joseph and Turnbull, Jeremy E. and Lauder, Robert M. and Fernig, David G. and Yates, Edwin A. (2009) The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids. Thrombosis and Haemostasis, 102 (5). pp. 874-878. ISSN 0340-6245

Sant'anna, Mauricio Rv and Diaz-Albiter, Hector and Mubaraki, Murad and Dillon, Rod J and Bates, Paul A (2009) Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania. Parasites and Vectors, 2: 62.

Saunders, Amy and Lamb, Tracey and Pascall, John and Hutchings, Amanda and Dion, Carine and Carter, Christine and Hepburn, Lucy and Langhorne, Jean and Butcher, Geoffrey W (2009) Expression of GIMAP1, a GTPase of the immunity-associated protein family, is not up-regulated in malaria. Malaria Journal, 8: 53. ISSN 1475-2875

Scull, Brooks and Rigby, Rachael J. and Newton, Victoria A. and Hamilton, Kathryn and Morgan, Douglas and Lund, Pauline K. (2009) Intestinal Epithelial Cell (IEC)-Specific Deletion of Suppressor of Cytokine Signaling 3 (SOCS3) in Interleukin-10 Null Mice Promotes Duodenal Tumors Independent of Inflammation: Detection with a Cathepsin-B Activatable Molecular Probe. Gastroenterology, 136 (5 Supp): 718. A114-A114. ISSN 0016-5085

Shih, B. and Brown, J.J. and Armstrong, D.J. and Lindau, T. and Bayat, A. (2009) Differential gene expression analysis of subcutaneous fat, fascia, and skin overlying a dupuytren's disease nodule in comparison to control tissue. Hand, 4 (3). pp. 294-301.

Shih, B. and Wijeratne, D. and Armstrong, D.J. and Lindau, T. and Day, Philip J. R. and Bayat, A. (2009) Identification of Biomarkers in Dupuytren's Disease by Comparative Analysis of Fibroblasts Versus Tissue Biopsies in Disease-Specific Phenotypes. Journal of Hand Surgery, 34 (1). pp. 124-136.

Sturzenbaum, Stephen R. and Andre, Jane and Kille, Peter and Morgan, A. John (2009) Earthworm genomes, genes and proteins : the (re)discovery of Darwin’s worms. Proceedings of the Royal Society B: Biological Sciences, 276 (1658). pp. 789-797. ISSN 0962-8452

Takaoka, Maho and Nakamura, Takahiro and Sugai, Hajime and Bentley, Adam James and Nakajima, Naoki and Yokoi, Norihiko and Fullwood, Nigel J. and Hyon, Suong-Hyu and Kinoshita, Shigeru (2009) Novel Sutureless Keratoplasty with a Chemically Defined Bioadhesive. Investigative Ophthalmology and Visual Science, 50 (6). pp. 2679-2685. ISSN 0146-0404

Taylor, David R and Parkin, Edward T and Cocklin, Sarah L and Ault, James R and Ashcroft, Alison E and Turner, Anthony J and Hooper, Nigel M (2009) Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein. Journal of Biological Chemistry, 284 (34). pp. 22590-22600. ISSN 0021-9258

Urbaniak, Michael D. (2009) Casein kinase 1 isoform 2 is essential for bloodstream form Trypanosoma brucei. Molecular and Biochemical Parasitology, 166 (2). pp. 183-185. ISSN 0166-6851

Urbaniak, Michael D. and Ferguson, Michael A J (2009) Chapter 3 The GlcNAc-PI de-N-acetylase. Structure, function, and activity. Enzymes, 26 (C). pp. 49-64. ISSN 1874-6047

Walsh, Michael John and Hammiche, Azzedine and Fellous, Tariq G. and Nicholson, James M. and Cotte, Marine and Susini, Jean and Fullwood, Nigel J. and Martin-Hirsch, Pierre L. and Alison, Malcolm R. and Martin, Frank L. (2009) Tracking the cell hierarchy in the human intestine using biochemical signatures derived by mid-infrared microspectroscopy. Stem Cell Research, 3 (1). pp. 15-27. ISSN 1873-5061

Wang, C. M. and Dixon, P. H. and Decordova, S. and Hodges, Matt and Seibre, N. J. and Ozalp, S. and Fallahian, M. and Sensi, A. and Ashrafi, F. and Repiska, V. and Zhao, J. and Xiang, Y. and Savage, P. M. and Seckl, M. J. and Fisher, R. A. (2009) Identification of 13 novel NLRP7 mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich region. Journal of Medical Genetics, 46 (8). pp. 569-575. ISSN 1468-6244

Zhao, Bojun and Ma, Aihua and Martin, Frank L. and Fullwood, Nigel J. (2009) An investigation into corneal alkali burns using an organ culture model. Cornea, 28 (5). pp. 541-546. ISSN 0277-3740