On the origin of influenza A hemagglutinin

Gatherer, Derek (2009) On the origin of influenza A hemagglutinin. Indian Journal of Microbiology, 49 (4). pp. 352-357. ISSN 0046-8991

Full text not available from this repository.

Abstract

Recent advances in phylogenetic methods have produced some reassessments of the ages of the most recent common ancestor of hemagglutinin proteins in known strains of influenza A. This paper applies Bayesian phylogenetic analysis implemented in BEAST to date the nodes on the influenza A hemagglutinin tree. The most recent common ancestor (MRCA) of influenza A hemagglutinin proteins is located with 95% confidence between 517 and 1497 of the Common Era (AD), with the center of the probability distribution at 1056 AD. The implications of this revised dating for both historical and current epidemiology are discussed. Influenza A can be seen as an emerging disease of mediaeval and early modern times.

Item Type:
Journal Article
Journal or Publication Title:
Indian Journal of Microbiology
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2400/2404
Subjects:
ID Code:
66844
Deposited By:
Deposited On:
27 Sep 2013 08:23
Refereed?:
Yes
Published?:
Published
Last Modified:
11 Feb 2020 08:15