Items where Author is "McKean, Paul G."

Journal Article

Harmer, Jane and Qi, Xin and Toniolo, Gabriella and Patel, Aysha and Shaw, Hannah and Benson, Fiona E. and Ginger, Michael L. and McKean, Paul G. (2017) Variation in Basal Body Localisation and Targeting of Trypanosome RP2 and FOR20 Proteins. Protist, 168 (4). pp. 452-466. ISSN 1434-4610

Sunter, Jack D. and Benz, Corinna and Andre, Jane and Whipple, Sarah and McKean, Paul G. and Gull, Keith and Ginger, Michael L. and Lukeš, Julius (2015) Modulation of flagellum attachment zone protein FLAM3 and regulation of the cell shape in Trypanosoma brucei life cycle transitions. Journal of Cell Science, 128 (16). pp. 3117-3130. ISSN 0021-9533

Ginger, Michael L. and McKean, Paul G. and Burchmore, Richard and Grant, Karen M. (2012) Proteomic insights into parasite biology. Parasitology, 139 (9). pp. 1101-1102. ISSN 0031-1820

Gluenz, Eva and Ginger, Michael L. and McKean, Paul G. (2010) Flagellum function and assembly during the Leishmania life cycle. Current Opinion in Microbiology, 13 (4). pp. 473-479. ISSN 1369-5274

Hart, Sarah R. and Wai Lau, King Wai and Hao, Zhiqi and Broadhead, Richard and Portman, Neil and Huhmer, Andreas and Gull, Keith and McKean, Paul G. and Hubbard, Simon J. and Gaskell, Simon J. (2009) Analysis of the trypanosome flagellar proteome using a combined electron transfer collisionally activated dissociation strategy. Journal of The American Society for Mass Spectrometry, 20 (2). pp. 167-175. ISSN 1044-0305

Portman, Neil and Lacomble, Sylvain and Thomas, Benjamin and McKean, Paul G. and Gull, Keith (2009) Combining RNA interference mutants and comparative proteomics to identify protein component interactions and dependencies in a eukaryotic flagellum. Journal of Biological Chemistry, 284 (9). pp. 5610-5619. ISSN 1083-351X

Ginger, Michael L. and Portman, Neil and McKean, Paul G. (2008) Swimming with protists : perception, motility and flagellum assembly. Nature Reviews in Microbiology, 6 (11). pp. 838-850. ISSN 1740-1534

Stephan, Angela and Vaughan, Sue and Shaw, Michael K. and Gull, Keith and McKean, Paul G. (2007) An essential quality control mechanism at the eukaryotic basal body prior to intraflagellar transport. Traffic, 8 (10). pp. 1323-1330. ISSN 1398-9219

Broadhead, Richard and Dawe, Helen R. and Farr, Helen and Griffiths, Samantha and Hart, Sarah R. and Portman, Neil and Shaw, Michael K. and Ginger, Michael L. and Gaskell, Simon J. and McKean, Paul G. and Gull, Keith (2006) Flagellar motility is required for the viability of the bloodstream trypanosome. Nature, 440 (7081). pp. 224-227. ISSN 0028-0836

Davidge, Jacqueline A. and Shawcross, Emma and Dickinson, Harriet A. and Towers, Katie and Ginger, Michael L. and McKean, Paul G. and Gull, Keith (2006) Trypanosome IFT mutants provide insight into the motor location for mobility of the flagella connector and flagella membrane formation. Journal of Cell Science, 119 (19). pp. 3935-3943. ISSN 0021-9533

Briggs, Laura and McKean, Paul G. and Baines, Andrea and Moreira-Leite, Flavia and Davidge, Jacqueline and Vaughan, Sue and Gull, Keith (2004) The flagella connector of Trypanosoma brucei : an unusual mobile transmembrane junction. Journal of Cell Science, 117 (9). pp. 1641-1651. ISSN 0021-9533

McKean, Paul G. (2003) Coordination of cell cycle progression and cytokinesis in Trypanosoma brucei. Current Opinion in Microbiology, 6 (6). pp. 600-607. ISSN 1369-5274

McKean, Paul G. and Baines, Andrea and Vaughan, Sue and Gull, Keith (2003) γ-Tubulin Functions in the Nucleation of a Discrete Subset of Microtubules in the Eukaryotic Flagellum. Current Biology, 13 (7). pp. 598-602. ISSN 0960-9822

Price, Helen and Menon, Malini R. and Panethymitaki, Chrysoula and Goulding, David and McKean, Paul G. and Smith, Deborah F. (2003) Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites. Journal of Biological Chemistry, 278 (9). pp. 7206-7214. ISSN 1083-351X

O'Dea, Kieran P. and McKean, Paul G. and Brown, K. Neil (2002) Plasmodium chabaudi chabaudi AS: modification of acute infection in CBA/Ca mice as a result of pre-treatment with erythrocyte band 3 in adjuvant. Experimental Parasitology, 102 (2). pp. 66-71. ISSN 0014-4894

McKean, Paul G. and Denny, Paul W. and Kneupfer, Ellen and Keen, Jane K. and Smith, Deborah F. (2001) Phenotypic changes associated with deletion and over-expression of a stage-regulated gene family in Leishmania. Cellular Microbiology, 3 (8). pp. 511-523. ISSN 1462-5814

McKean, Paul G. and Vaughan, Sue and Gull, Keith (2001) The extended tubulin superfamily. Journal of Cell Science, 114 (15). pp. 2723-2733. ISSN 0021-9533

Kneupfer, Ellen and Stierhof, Y. D. and McKean, Paul G. and Smith, Deborah F. (2001) Characterisation of a differentially expressed protein that shows an unusual localisation to intracellular membranes in Leishmania major. Biochemical Journal, 356 (2). pp. 335-344. ISSN 0264-6021

McKean, Paul G. and Keen, J. K. and Kelly, J. M. and Smith, Deborah F. (2000) Molecular parasitology : new insights. Parasitology Today, 15 (12). pp. 469-470. ISSN 0169-4758

Vaughan, Susan and Attwood, Teresa and Navarro, Miguel and Scott, Valerie and McKean, Paul G. and Gull, Keith (2000) New tubulins in protozoal parasites. Current Biology, 10 (7). R258-259. ISSN 0960-9822

McKean, Paul G. and Trenholme, Katharine R. and Rangarajan, Desikan and Keen, Jane K. and Smith, Deborah F. (1997) Diversity in repeat-containing surface proteins of Leishmania major. Molecular and Biochemical Parasitology, 86 (2). pp. 225-235. ISSN 0166-6851

McKean, Paul G. and Delahay, Rob and Pimenta, Paulo F. and Smith, Deborah F. (1997) Characterisation of a second protein encoded by the differentially regulated LmcDNA16 gene family of Leishmania major. Molecular and Biochemical Parasitology, 85 (2). pp. 221-231. ISSN 0166-6851

O’Dea, K. P. and McKean, Paul G. and Jarra, W. and Brown, K. N. (1996) A single gene copy merozoite surface antigen and immune evasion? Parasite Immunology, 18 (4). pp. 165-172. ISSN 1365-3024

O’Dea, Kieran P. and McKean, Paul G. and Harris, Alan and Brown, K. Neil (1995) Processing of the Plasmodium chabaudi chabaudi AS merozite surface protein 1 in vivo and in vitro. Molecular and Biochemical Parasitology, 72 (1-2). pp. 111-119. ISSN 0166-6851

Smith, D. F. and Gokool, S. and Keen, J. K. and McKean, Paul G. and Rangarajan, Desikan (1994) Structure and function of infective stage proteins of Leishmania. Biochemical Society Transactions, 22 (2). pp. 286-291. ISSN 1470-8752

McKean, Paul G. and O’Dea, Keiran P. and Brown, K. Neil (1993) Nucleotide sequence analysis and epitope mapping of the merozoite surface protein 1 from Plasmodium chabaudi chabaudi AS. Molecular and Biochemical Parasitology, 62 (2). pp. 199-209. ISSN 0166-6851

McKean, Paul G. and O'Dea, Keiran P. and Brown, K. Neil (1993) A single amino acid determines the specificity of a monoclonal antibody which inhibits Plasmodium chabaudi AS in vivo. Molecular and Biochemical Parasitology, 62 (2). pp. 211-221. ISSN 0166-6851

Pritchard, D. I. and Quinnell, R. J. and McKean, Paul G. and Walsh, L. and Leggett, K. V. and Slater, A. F. and Raiko, A. and Dale, D. D. and Keymer, A. E. (1991) Antigenic cross-reactivity between Necator americanus and Ascaris lumbricoides in a community in Papua New Guinea infected predominantly with hookworm. Transactions of The Royal Society of Tropical Medicine and Hygiene, 85 (4). pp. 511-514. ISSN 0035-9203

Pritchard, D. I. and Leggett, K. V. and Rogan, M. T. and McKean, Paul G. and Brown, Alan (1991) Necator americanus secretory acetylcholinesterase and its purification from excretory-secretory products by affinity chromatography. Parasite Immunology, 13 (2). pp. 187-199. ISSN 1365-3024

Pritchard, D. I. and Quinnell, R. J. and Moustafa, M. and McKean, Paul G. and Slater, A. F. and Raiko, A. and Dale, D. D. and Keymer, A. E. (1991) Hookworm (Necator americanus) infection and storage iron depletion. Transactions of The Royal Society of Tropical Medicine and Hygiene, 85 (2). pp. 235-238. ISSN 0035-9203

Pritchard, D. I. and Quinnell, R. J. and Slater, A. F. and McKean, Paul G. and Dale, D. D. and Raiko, A. and Keymer, A. E. (1990) The epidemiological significance of the immune response to the cuticular collagen of Necator americanus : a preliminary study in a hookworm-endemic area in Papua New Guinea. Acta Tropica, 47 (5-6). pp. 403-407. ISSN 0001-706X

Pritchard, D. I. and McKean, Paul G. and Rogan, M. T. and Schad, G. A. (1990) The identification of a species-specific antigen from Necator americanus. Parasite Immunology, 12 (3). pp. 259-267. ISSN 1365-3024

Pritchard, D. I. and McKean, Paul G. and Schad, G. A. (1990) An immunological and biochemical comparison of hookworm species. Parasitology Today, 6 (5). pp. 154-156. ISSN 0169-4758

Pritchard, David Idris and Quinnell, R. J. and Slater, A. F. and McKean, Paul G. and Dale, D. D. and Raiko, A. and Keymer, A. E. (1990) Epidemiology and immunology of Necator americanus infection in a community in Papua New Guinea: humoral responses to excretory-secretory and cuticular collagen antigens. Parasitology, 100 (2). pp. 317-326. ISSN 0031-1820

McKean, Paul G. and Pritchard, D. I. (1989) The action of a mast cell protease on the cuticular collagens of Necator americanus. Parasite Immunology, 11 (3). pp. 293-297. ISSN 1365-3024

Pritchard, David Idris and McKean, Paul G. and Rogan, Michael Thomas (1988) Cuticular collagens – a concealed target for immune attack in hookworms. Parasitology Today, 4 (9). pp. 239-241. ISSN 0169-4758

Pritchard, David Idris and McKean, Paul G. and Rogan, Michael Thomas (1988) Cuticle preparations from Necator americanus and their immunogenicity in the infected host. Molecular and Biochemical Parasitology, 28 (3). pp. 275-283. ISSN 0166-6851

Contribution in Book/Report/Proceedings

Hammarton, Tansy and Wickstead, Bill and McKean, Paul G. (2007) Cell structure, cell division and cell cycle. In: Trypanosomes : after the genome :. Horizon Bioscience, Wymondham, pp. 239-280. ISBN 978-1-904933-27-4

Pritchard, D. I. and McKean, Paul G. and Quinnell, R. J. and Tighe, P. J. (1991) Recent and predicted advances in hookworm biology. In: Parasitic Nematodes: Membranes, Antigens and Genes. :. Taylor & Francis, London, pp. 140-169. ISBN 0850667720