Items where Author is "Dawson, Neil"

Bryers, Amelia and Hawkes, Cheryl A and Parkin, Edward and Dawson, Neil (2024) Progress towards understanding risk factor mechanisms in the development of autism spectrum disorders. Biochemical Society Transactions, 52 (5). pp. 2047-2058. ISSN 0300-5127

Armstrong, Paul and Güngör, Hüseyin and Anongjanya, Pariya and Tweedy, Clare and Parkin, Edward and Johnston, Jamie and Carr, Ian M and Dawson, Neil and Clapcote, Steven J (2024) Protective effect of PDE4B subtype-specific inhibition in an App knock-in mouse model for Alzheimer's disease. Neuropsychopharmacology, 49 (10). pp. 1559-1568. ISSN 0893-133X

Reich, Niklas and Parkin, Edward and Dawson, Neil (2024) Liposome nanoparticle conjugation and cell penetrating peptide sequences ( CPPs ) enhance the cellular delivery of the tau aggregation inhibitor RI ‐ AG03. Journal of Cellular and Molecular Medicine, 28 (11): e18477. ISSN 1582-1838

Reich, Niklas and Dawson, Neil and Parkin, Edward (2023) Investigation of a Tau aggregation inhibitor peptide and peptide-conjugated liposomes as a potential treatment for Alzheimer’s Disease. PhD thesis, Lancaster University.

Openshaw, Rebecca L. and Thomson, David M. and Bristow, Greg C. and Mitchell, Emma J. and Pratt, Judith A. and Morris, Brian J. and Dawson, Neil (2023) 16p11.2 deletion mice exhibit compromised fronto-temporal connectivity, GABAergic dysfunction, and enhanced attentional ability. Communications Biology, 6 (1).

Owens, Lauren and Parkin, Edward and Benedetto, Alexandre and Gaffney, Christopher and Dawson, Neil (2023) The Role of Fibrates and Soluble Amyloid Precursor Alpha in Alzheimer’s Disease and Longevity. PhD thesis, Lancaster University.

Hughes, Rebecca and Whittingham-Dowd, Jayde and Clapcote, Stephen and Broughton, Susan and Dawson, Neil (2022) Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behaviour in a mouse model of autism-associated 2p16.3 deletion. Autism Research, 15 (4). pp. 614-627. ISSN 1939-3792

Owens, Lauren and Bracewell, Joshua and Benedetto, Alex and Dawson, Neil and Gaffney, Christopher and Parkin, Edward (2022) BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation : Beta Prime-Mediated Competitive Depletion of sAβPPα. Journal of Alzheimer's Disease, 86 (3). pp. 1201-1220. ISSN 1387-2877

Tanqueiro, Sara R and Mouro, Francisco M and Ferreira, Catarina B and Freitas, Céline F and Fonseca-Gomes, João and Simões do Couto, Frederico and Sebastião, Ana M and Dawson, Neil and Diógenes, Maria J (2021) Sustained NMDA receptor hypofunction impairs brain-derived neurotropic factor signalling in the PFC, but not in the hippocampus, and disturbs PFC-dependent cognition in mice. Journal of Psychopharmacology, 35 (6). pp. 730-743. ISSN 0269-8811

Owens, Lauren and Benedetto, Alex and Dawson, Neil and Gaffney, Christopher and Parkin, Edward (2021) Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer's disease. Brain Research, 1753: 147264. ISSN 0006-8993

Mitchell, Emma J and Thomson, David M and Openshaw, Rebecca L and Bristow, Greg C. and Dawson, Neil and Pratt, Judith A and Morris, Brian J (2020) Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model : a central role for gene-environment interactions. Scientific Reports, 10 (1): 12303. ISSN 2045-2322

Pytka, Karolina and Dawson, Neil and Tossell, Kyoko and Ungless, Mark A and Plevin, Robin and Brett, Ros R and Bushell, Trevor J (2020) Mitogen-activated protein kinase phosphatase-2 deletion modifies ventral tegmental area function and connectivity and alters reward processing. European Journal of Neuroscience, 52 (2). pp. 2838-2852. ISSN 0953-816X

Ellis, Jodie and Dawson, Neil (2020) Characterising gut dysbiosis in rodent models relevant to psychiatric and neurodevelopmental disorders. Masters thesis, Lancaster University.

Bristow, Greg C. and Thomson, David M and Openshaw, Rebecca L and Mitchell, Emma J and Pratt, Judith A and Dawson, Neil and Morris, Brian J (2020) 16p11 Duplication Disrupts Hippocampal-Orbitofrontal-Amygdala Connectivity, Revealing a Neural Circuit Endophenotype for Schizophrenia. Cell Reports, 31 (3): 107536. ISSN 2211-1247

Hughes, Rebecca and Whittingham-Dowd, Jayde and Simmons, Rachel and Clapcote, Stephen and Broughton, Susan and Dawson, Neil (2020) Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion. Cerebral Cortex (4). 2358–2371. ISSN 1047-3211

Openshaw, Rebecca L and Thomson, David M and Thompson, Rhiannon and Penninger, Josef M and Pratt, Judith A and Morris, Brian J and Dawson, Neil (2020) Map2k7 Haploinsufficiency Induces Brain Imaging Endophenotypes and Behavioral Phenotypes Relevant to Schizophrenia. Schizophrenia Bulletin, 46 (1). pp. 211-223. ISSN 0586-7614

Fathallah, Nadin and Dawson, Neil and Urbaniak, Mick (2020) The development of novel experimental strategies for elucidating the role of tryptophan metabolism in the neuropsychopathology of Human African Trypanosomiasis. PhD thesis, Lancaster University.

Pratt, Judith A and Morris, Brian and Dawson, Neil (2019) Deconstructing Schizophrenia : Advances in Preclinical Models for Biomarker Identification. In: Current Topics in Behavioral Neurosciences :. Springer, Berlin, pp. 295-323. ISBN 9783319996417

Hughes, Rebecca and Dawson, Neil and Broughton, Susan (2019) Characterisation of neurodevelopmental disorder and ageing phenotypes in transgenic mouse and fruit fly models of Neurexin1 dysfunction. PhD thesis, Lancaster University.

Mouro, Francisco M and Ribeiro, Joaquim A and Sebastião, Ana M and Dawson, Neil (2018) Chronic, intermittent treatment with a cannabinoid receptor agonist impairs recognition memory and brain network functional connectivity. Journal of Neurochemistry, 147 (1). pp. 71-83. ISSN 0022-3042

Dauvermann, Maria R. and Lee, Graham and Dawson, Neil (2017) Glutamatergic regulation of cognition and functional brain connectivity : insights from pharmacological, genetic and translational schizophrenia research. British Journal of Pharmacology, 174 (19). pp. 3136-3160. ISSN 0007-1188

Pratt, Judith and Dawson, Neil and Morris, Brian J. and Grent-'t-Jong, Tineke and Roux, Frederic and Uhlhaas, Peter J. (2017) Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations : a unique window into the origins of ScZ? Schizophrenia Research, 180. pp. 4-12. ISSN 0920-9964

Martin, Adrian and Coolsaet, Brendan and Corbera, Esteve and Dawson, Neil and Fraser, James Angus and Lehmann, Ina and Rodriguez, Iokiñe (2016) Justice and conservation : the need to incorporate recognition. Biological Conservation, 197. pp. 254-261. ISSN 0006-3207

Dawson, Neil and Kurihara, Mai and Thomson, D. M. and Winchester, C. L. and McVie, A. and Hedde, J. R. and Randall, A. D. and Shen, Sanbing and Seymour, P. A. and Hughes, Z. A. and Dunlop, John and Brown, J. T. and Brandon, N. J. and Morris, B. J. and Pratt, Judith A. (2015) Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1. Translational Psychiatry, 5: e569.

Dawson, Neil and Morris, Brian J. and Pratt, Judith (2015) Functional brain connectivity phenotypes for schizophrenia drug discovery. Journal of Psychopharmacology, 29 (2). pp. 169-177. ISSN 0269-8811

Dawson, Neil and McDonald, Martin and Higham, Desmond J and Morris, Brian J and Pratt, Judith A (2014) Subanaesthetic ketamine treatment promotes abnormal interactions between neural subsystems and alters the properties of functional brain networks. Neuropsychopharmacology, 39 (7). pp. 1786-1798. ISSN 0893-133X

Dawson, Neil and Xiao, Xiaolin and McDonald, Martin and Higham, Desmond J. and Morris, Brian J. and Pratt, Judith A. (2014) Sustained NMDA receptor hypofunction induces compromised neural systems integration and schizophrenia-like alterations in functional brain networks. Cerebral Cortex, 24 (2). pp. 452-464. ISSN 1047-3211

Kirshenbaum, Greer and Dawson, Neil and Mullins, Jonathan and Johnston, Tom and Drinkhill, Mark and Edwards, Ian and Fox, Susan and Pratt, Judith and Brotchie, Jonathan and Roder, John and Clapcote, Stephen (2013) Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+, K+-ATPase a3 missense mutant mice. PLoS ONE, 8 (3): e60141. ISSN 1932-6203

Dawson, Neil and Morris, Brian J. and Pratt, Judith A. (2013) Subanaesthetic ketamine treatment alters prefrontal cortex connectivity with thalamus and ascending subcortical systems. Schizophrenia Bulletin, 39 (2). pp. 366-377. ISSN 0586-7614

Dawson, Neil and Thompson, Rhiannon J. and McVie, Allan and Thomson, David M. and Morris, Brian J. and Pratt, Judith A. (2012) Modafinil reverses phencyclidine-induced deficits in cognitive flexibility, cerebral metabolism and functional brain connectivity. Schizophrenia Bulletin, 38 (3). pp. 457-474. ISSN 0586-7614

Pratt, Judith and Winchester, Catherine and Dawson, Neil and Morris, Brian (2012) Advancing schizophrenia drug discovery : optimizing rodent models to bridge the translational gap. Nature Reviews Drug Discovery, 11. pp. 560-579. ISSN 1474-1784

Xiao, Xiaolin and Dawson, Neil and MacIntyre, Lynsey and Morris, Brian and Pratt, Judith and Watson, David and Higham, Desmond (2011) Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the generalized singular value decomposition. BMC Systems Biology, 5: 72.

Dawson, Neil and Ferrington, Linda and Lesch, Klaus-Peter and Kelly, Paul (2011) Cerbral metabolic responses to 5-HT2A/C receptor activation in mice with genetically modified serotonin transporter (SERT) expression. European Neuropsychopharmacology, 21 (1). pp. 117-128. ISSN 1873-7862

van Donkelaar, Eva and Kelly, Paul and Dawson, Neil and Blokland, Arjan and Prickaerts, Jos and Steinbusch, Harry and Ferrington, Linda (2010) Acute tryptophan depletion potentiates 3,4-methylenedioxymethamphetamine-induced cerebrovascular hyperperfusion in rats. Journal of Neuroscience Research, 88 (7). pp. 1557-1568. ISSN 0360-4012

Dawson, Neil and Ferrington, Linda and Olverman, Henry and Harmar, Anthony and Kelly, Paul (2009) Sex influences the effect of a lifelong increase in serotonin transporter function on cerebral metabolism. Journal of Neuroscience Research, 87 (10). pp. 2375-2385. ISSN 0360-4012