Items where Author is "Owen-Lynch, P J"

Barnes, N A and Owen-Lynch, P J (2005) Regulation of FKHR, GSK-3beta and cyclins D1 and D2 by interleukin-3 in haematopoietic progenitor cells. Experimental Hematology, 33 (7 Supp). p. 46. ISSN 0301-472X

Xenaki, D and Gray, A and Downes, C P and Owen-Lynch, P J (2001) A novel tool for the detection of phosphatidylinositol-(3,4,5)-trisphosphate in primitive hematopoietic stem cells: Characterization of the response to IL-3 and Bcr-Abl. Blood, 98 (11). 290A-291A. ISSN 0006-4971

Bentley, J and Tang, C W and Owen-Lynch, P J and Downes, C P and Baldwin, S A and Whetton, A D (1999) The survival signals stimulated by interleukin 3 include a phosphatidylinositol 3 kinase/PKB mediated translocation of the GLUT 1 glucose transporter to the cell surface. Blood, 94 (10). 471A-471A. ISSN 0006-4971

Pierce, A and Owen-Lynch, P J and Spooncer, E and Dexter, T M and Whetton, A D (1998) p210 Bcr-Abl expression in a primitive multipotent haematopoietic cell line models the development of chronic myeloid leukaemia. Oncogene, 17 (5). pp. 667-672. ISSN 0950-9232

Pierce, A and Heyworth, C M and Nicholls, S E and Spooncer, E and Dexter, T M and Lord, J M and Owen-Lynch, P J and Wark, G and Whetton, A D (1998) An activated protein kinase C alpha gives a differentiation signal for hematopoietic progenitor cells and mimicks macrophage colony-stimulating factor-stimulated signaling events. Journal of Cell Biology, 140 (6). pp. 1511-1518. ISSN 0021-9525

Pierce, A and Whetton, A D and Owen-Lynch, P J and Tavernier, J and Spooncer, E and Dexter, T M and Heyworth, C M (1998) Ectopic interleukin-5 receptor expression promotes proliferation without development in a multipotent hematopoietic cell line. Journal of Cell Science, 111 (6). pp. 815-823. ISSN 0021-9533

Pearson, M A and O'Farrell, A M and Dexter, T M and Whetton, A D and Owen-Lynch, P J and Heyworth, C M (1998) Investigation of the molecular mechanisms underlying growth factor synergy : the role of ERK 2 activation in synergy. Growth Factors, 15 (4). pp. 293-306. ISSN 0897-7194

Owen-Lynch, P J and Czaplewski, L G and Hunter, M G and Whetton, A D (1998) The growth inhibitory role and potential clinical value of macrophage inflammatory protein 1 alpha in myeloid leukaemias. Leukemia and Lymphoma, 30 (1-2). pp. 41-53. ISSN 1042-8194

Owen-Lynch, P J and Adams, J A and Brereton, M L and Czaplewski, L G and Whetton, A D and Yin, J A (1996) The effect of the chemokine rhMIP-1 alpha, and a non-aggregating variant BB-10010, on blast cells from patients with acute myeloid leukaemia. British Journal of Haematology, 95 (1). pp. 77-84. ISSN 0007-1048

Chasty, R C and Lucas, G S and Owen-Lynch, P J and Pierce, A and Whetton, A D (1995) Macrophage inflammatory protein-1 alpha receptors are present on cells enriched for CD34 expression from patients with chronic myeloid leukemia. Blood, 86 (11). pp. 4270-4277. ISSN 0006-4971

Evans, C A and Lord, J M and Owen-Lynch, P J and Johnson, G and Dive, C and Whetton, A D (1995) Suppression of apoptosis by v-ABL protein tyrosine kinase is associated with nuclear translocation and activation of protein kinase C in an interleukin-3-dependent haemopoietic cell line. Journal of Cell Science, 108 (7). pp. 2591-2598. ISSN 0021-9533

Owen-Lynch, P J and Wong, A K and Whetton, A D (1995) v-Abl-mediated apoptotic suppression is associated with SHC phosphorylation without concomitant mitogen-activated protein kinase activation. Journal of Biological Chemistry, 270 (11). pp. 5956-5962. ISSN 0021-9258

Heyworth, C M and Pearson, M A and Dexter, T M and Wark, G and Owen-Lynch, P J and Whetton, A D (1995) Macrophage inflammatory protein-1 alpha mediated growth inhibition in a haemopoietic stem cell line is associated with inositol 1,4,5 triphosphate generation. Growth Factors, 12 (3). pp. 165-172. ISSN 0897-7194

Whetton, A D and Heyworth, C M and Nicholls, S E and Evans, C A and Lord, J M and Dexter, T M and Owen-Lynch, P J (1994) Cytokine-mediated protein kinase C activation is a signal for lineage determination in bipotential granulocyte macrophage colony-forming cells. Journal of Cell Biology, 125 (3). pp. 651-659. ISSN 0021-9525

Spooncer, E and Fairbairn, L and Cowling, G J and Dexter, T M and Whetton, A D and Owen-Lynch, P J (1994) Biological consequences of p160v-abl protein tyrosine kinase activity in a primitive, multipotent haemopoietic cell line. Leukemia, 8 (4). pp. 620-630. ISSN 0887-6924

Evans, C A and Owen-Lynch, P J and Whetton, A D and Dive, C (1993) Activation of the Abelson tyrosine kinase activity is associated with suppression of apoptosis in hemopoietic cells. Cancer Research, 53 (8). pp. 1735-1738. ISSN 0008-5472