Items where Author is "McClean, Paula L."

Journal Article

McClean, Paula L. and Jalewa, Jaishree and Holscher, Christian (2015) Prophylactic liraglutide treatment prevents amyloid plaque deposition, chronic inflammation and memory impairment in APP/PS1 mice. Behavioural Brain Research, 293. pp. 96-106. ISSN 0166-4328

Kelly, Patricia and McClean, Paula L. and Ackermann, Maximilian and Konerding, Moritz A. and Holscher, Christian and Mitchell, Christopher A. (2015) Restoration of cerebral and systemic microvascular architecture in APP/PS1 transgenic mice following treatment with Liraglutide™. Microcirculation, 22 (2). pp. 133-145. ISSN 1549-8719

McClean, Paula L. and Holscher, Christian (2014) Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease. Neuropharmacology, 86. pp. 241-258. ISSN 0028-3908

Long-Smith, Caitriona M. and Manning, Sean and McClean, Paula L. and Coakley, Meghan F. and O'Halloran, Domhnall J. and Holscher, Christian and O'Neill, Cora (2013) The diabetes drug liraglutide ameliorates aberrant insulin receptor localisation and signalling in parallel with decreasing both amyloid-β plaque and glial pathology in a mouse model of Alzheimer's disease. NeuroMolecular Medicine, 15 (1). pp. 102-114. ISSN 1559-1174

McClean, Paula L. and Holscher, Christian (2013) Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer ‘s disease. Neuropharmacology, 76 (Part A). pp. 57-67. ISSN 0028-3908

Bomfim, Theresa R. and Forny-Germano, Leticia and Sathler, Luciana B. and Brito-Moreira, Jordano and Houzel, Jean-Christophe and Decker, Helena and Silverman, Michael A. and Kazi, Hala and Melo, Helen M. and McClean, Paula L. and Holscher, Christian and Arnold, Steven E. and Talbot, Konrad and Klein, William L. and Munoz, Douglas P. and Ferreira, Sergio T. and De Felice, Fernanda G. (2012) An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers. Journal of Clinical Investigation, 122 (4). pp. 1339-1353. ISSN 1558-8238

Gengler, Simon and McClean, Paula L. and McCurtin, Ruth and Gault, Victor A. and Holscher, Christian (2012) Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice. Neurobiology of Aging, 33 (2). pp. 265-276. ISSN 0197-4580

McClean, Paula L. and Parthsarathy, Vadivel and Faivre, Emilie and Holscher, Christian (2011) The diabetes drug Liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease. Journal of Neuroscience, 31 (17). pp. 6587-6594. ISSN 0270-6474

McClean, Paula L. and Gault, Victor A. and Harriott, Patrick and Hölscher, Christian (2010) Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain : a link between diabetes and Alzheimer's disease. European Journal of Pharmacology, 630 (1-3). pp. 158-162. ISSN 0014-2999