Items where Author is "Jaki, Thomas Friedrich"

Mozgunov, Pavel and Jaki, Thomas Friedrich (2020) An information-theoretic approach for selecting arms in clinical trials. Journal of the Royal Statistical Society: Series B (Statistical Methodology), 82 (5). pp. 1223-1247. ISSN 1369-7412

Mozgunov, Pavel and Jaki, Thomas Friedrich and Paoletti, Xavier (2020) A benchmark for dose finding studies with continuous outcomes. Biostatistics, 21 (2). 189–201. ISSN 1465-4644

Mozgunov, Pavel and Jaki, Thomas Friedrich and Gasparini, Mauro (2019) Loss Functions in Restricted Parameter Spaces and Their Bayesian Applications. Journal of Applied Statistics, 46 (13). pp. 2314-2337. ISSN 0266-4763

Saint-Hilary, Gaelle and Robert, Veronique and Gasparini, Mauro and Jaki, Thomas Friedrich and Mozgunov, Pavel (2019) A novel measure of drug benefit–risk assessment based on Scale Loss Score. Statistical Methods in Medical Research, 28 (9). pp. 2738-2753. ISSN 0962-2802

Vradi, Eleni and Jaki, Thomas Friedrich and Vonk, Richardus and Brannath, Werner (2019) A Bayesian model to estimate the cutoff and the clinical utility of a biomarker assay. Statistical Methods in Medical Research, 28 (8). pp. 2538-2556. ISSN 0962-2802

Jaki, Thomas Friedrich and Kim, Minjung and Lamont, Andrea E. and George, M. and Feaster, Daniel and Van Horn, M. Lee (2019) The effects of sample size on the estimation of regression mixture models. Educational and Psychological Measurement, 79 (2). pp. 358-384. ISSN 0013-1644

Brueckner, Matthias and Titman, Andrew Charles and Jaki, Thomas Friedrich (2019) Instrumental variable estimation in semi-parametric additive hazards models. Biometrics, 75 (1). pp. 110-120. ISSN 0006-341X

Jaki, Thomas Friedrich and Pallmann, Philip Steffen and Magirr, Dominic (2019) The R package MAMS for designing multi-arm multi-stage clinical trials. Journal of Statistical Software, 88 (4). ISSN 1548-7660

Wan, Fang and Kunz, Cornelia Ursula and Jaki, Thomas Friedrich (2019) Confidence regions for treatment effects in subgroups in biomarker stratified designs. Biometrical Journal, 61 (1). pp. 27-39. ISSN 0323-3847

Kunz, Cornelia Ursula and Jaki, Thomas Friedrich and Stallard, Nigel (2018) An alternative method to analyse the Biomarker-strategy design. Statistics in Medicine, 37 (30). pp. 4636-4651. ISSN 0277-6715

Chiu, Yi-Da and Koenig, Franz and Posch, Martin and Jaki, Thomas Friedrich (2018) Design and estimation in clinical trials with subpopulation selection. Statistics in Medicine, 37 (29). pp. 4335-4352. ISSN 0277-6715

Mozgunov, Pavel and Jaki, Thomas Friedrich and Paoletti, Xavier (2018) Randomized dose-escalation designs for drug combination cancer trials with immunotherapy. Journal of Biopharmaceutical Statistics, 29 (2). pp. 359-377. ISSN 1054-3406

Brueckner, Matthias and Titman, Andrew Charles and Jaki, Thomas Friedrich and Rojek, Amanda and Horby, Peter W. (2018) Performance of different clinical trial designs to evaluate treatments during an epidemic. PLoS ONE, 13 (9): e0203387. ISSN 1932-6203

Cotterill, Amy and Jaki, Thomas Friedrich (2018) Dose-escalation strategies which utilise subgroup information. Pharmaceutical Statistics, 17 (5). pp. 414-436. ISSN 1539-1604

Jaki, Thomas Friedrich and Gordon, A and Forster, Pamela Suzanne and Bijnens, L and Bornkamp, B and Brannath, Werner and Fontana, Roberto and Gasparini, Mauro and Hampson, Lisa Victoria and Jacobs, Tom and Jones, Byron and Paoletti, Xavier and Posch, Martin and Titman, Andrew Charles and Vonk, Richardus and Koenig, Franz (2018) A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharmaceutical Statistics, 17 (5). pp. 593-606. ISSN 1539-1604

Mozgunov, Pavel and Jaki, Thomas Friedrich (2018) An information-theoretic Phase I/II design for molecularly targeted agents that does not require an assumption of monotonicity. Journal of the Royal Statistical Society: Series C (Applied Statistics), 68 (2). pp. 347-367. ISSN 0035-9254

Mozgunov, Pavel and Beccuti, Marco and Horvath, Andras and Jaki, Thomas Friedrich and Sirovich, Roberta and Bibbona, Enrico (2018) A review of the deterministic and diffusion approximations for stochastic chemical reaction networks. Reaction Kinetics, Mechanisms and Catalysis, 123 (2). pp. 289-312. ISSN 1878-5190

Wadsworth, Ian and Hampson, Lisa Victoria and Jaki, Thomas Friedrich (2018) Extrapolation of efficacy and other data to support the development of new medicines for children : a systematic review of methods. Statistical Methods in Medical Research, 27 (2). pp. 398-413. ISSN 0962-2802

Lamont, Andrea E. and Lyons, Mike and Jaki, Thomas Friedrich and Stuart, E. A. and Feaster, Daniel and Ishwaran, H. and Tharmaratnam, Kukatharmini and Van Horn, M. Lee (2018) Identification of Predicted Individual Treatment Effects (PITE) in randomized clinical trials. Statistical Methods in Medical Research, 27 (1). pp. 142-157. ISSN 0962-2802

Su, Ting-Li and Jaki, Thomas Friedrich and Hickey, Graeme and Buchan, Iain and Sperrin, Matthew (2018) A review of statistical updating methods for clinical prediction models. Statistical Methods in Medical Research, 27 (1). pp. 185-197. ISSN 0962-2802

Barnett, Helen Yvette and Geys, Helena and Jacobs, Tom and Jaki, Thomas Friedrich (2018) Optimal Designs for Non-Compartmental Analysis of Pharmacokinetic Studies. Statistics in Biopharmaceutical Research, 10 (4). pp. 255-263. ISSN 1946-6315

Pallmann, Philip Steffen and Jaki, Thomas Friedrich (2017) Simultaneous confidence regions for multivariate bioequivalence. Statistics in Medicine, 36 (29). pp. 4585-4603. ISSN 0277-6715

Brueckner, Matthias and Titman, Andrew Charles and Jaki, Thomas Friedrich (2017) Estimation in multi-arm two-stage trials with treatment selection and time-to-event endpoint. Statistics in Medicine, 36 (20). pp. 3137-3153. ISSN 0277-6715

Williamson, Faye and Jacko, Peter and Villar, Sofia Soledad and Jaki, Thomas Friedrich (2017) A Bayesian adaptive design for clinical trials in rare diseases. Computational Statistics and Data Analysis, 113. pp. 136-153. ISSN 0167-9473

Jaki, Thomas Friedrich and Vasileiou, Despoina (2017) Factorial versus multi-arm multi-stage designs for clinical trials with multiple treatments. Statistics in Medicine, 36 (4). pp. 563-580. ISSN 0277-6715

Hampson, Lisa Victoria and Fisch, Roland and Van, Linh M. and Jaki, Thomas Friedrich (2017) Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children. Statistics in Medicine, 36 (3). pp. 426-441. ISSN 0277-6715

Wadsworth, Ian and Jaki, Thomas Friedrich and Sills, Graeme J. and Appleton, Richard and Cross, J. Helen and Marson, Anthony G. and Martland, Timothy and McLellan, Ailsa and Smith, Philip E. M. and Pellock, John M. and Hampson, Lisa Victoria (2016) Clinical drug development in epilepsy revisited : a proposal for a new paradigm streamlined using extrapolation. CNS Drugs, 30 (11). pp. 1011-1017. ISSN 1172-7047

Jaki, Thomas Friedrich and Allacher, Peter and Horling, Frank (2016) A false sense of security? : can tiered approach be trusted to accurately classify immunogenicity samples? Journal of Pharmaceutical and Biomedical Analysis, 128. pp. 166-173. ISSN 0731-7085

Tharmaratnam, Kukatharmini and Sperrin, Matthew and Jaki, Thomas Friedrich and Reppe, Sjur and Frigessi, Arnoldo (2016) Tilting the lasso by knowledge-based post-processing. BMC Bioinformatics, 17: 344. ISSN 1471-2105

Brown, Benjamin and Cheraghi-Sohi, Sudeh and Jaki, Thomas Friedrich and Su, Ting-Li and Buchan, Iain and Sperrin, Matthew (2016) Understanding clinical prediction models as ‘innovations’ : a mixed methods study in UK family practice. BMC Medical Informatics and Decision Making, 16: 106.

Jaki, Thomas Friedrich and Parry, Alice (2016) Why are two mistakes not worse than one? : a proposal for controlling the expected number of false claims. Pharmaceutical Statistics, 15 (4). pp. 362-367. ISSN 1539-1604

Kim, Minjung and Vermunt, Joeren and Bakk, Zsuzsa and Jaki, Thomas Friedrich and Van Horn, M. Lee (2016) Modeling predictors of latent classes in regression mixture models. Structural Equation Modeling, 23 (4). pp. 601-614. ISSN 1070-5511

Magirr, Dominic and Jaki, Thomas Friedrich and Koenig, Franz and Posch, Martin (2016) Sample size reassessment and hypothesis testing in adaptive survival trials. PLoS ONE, 11 (2): e0146465. ISSN 1932-6203

Yeung, Wai Yin and Whitehead, John Raymond and Reigner, Bruno and Beyer, Ulrich and Diack, Cheikh and Jaki, Thomas Friedrich (2015) Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function. Pharmaceutical Statistics, 14 (6). pp. 479-487. ISSN 1539-1604