Items where Author is "Hall, Steven R"
Dawson, Charlotte A and Bartlett, Keirah E and Wilkinson, Mark C and Ainsworth, Stuart and Albulescu, Laura-Oana and Kazandijan, Taline and Hall, Steven R and Westhorpe, Adam and Clare, Rachel and Wagstaff, Simon and Modahl, Cassandra M and Harrison, Robert A and Casewell, Nicholas R (2024) Intraspecific venom variation in the medically important puff adder (Bitis arietans) : Comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom. PLoS Neglected Tropical Diseases, 18 (10): e0012570. ISSN 1935-2727
Du, Tian Y and Hall, Steven R and Chung, Felicity and Kurdyukov, Sergey and Crittenden, Edouard and Patel, Karishma and Dawson, Charlotte A and Westhorpe, Adam P and Bartlett, Keirah E and Rasmussen, Sean A and Moreno, Cesar L and Denes, Christopher E and Albulescu, Laura-Oana and Marriott, Amy E and Mackay, Joel P and Wilkinson, Mark C and Gutiérrez, José María and Casewell, Nicholas R and Neely, G Gregory (2024) Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming. Science Translational Medicine, 16 (756): eadk4802. ISSN 1946-6234
Hall, Steven R and Rasmussen, Sean A and Crittenden, Edouard and Dawson, Charlotte A and Bartlett, Keirah E and Westhorpe, Adam P and Albulescu, Laura-Oana and Kool, Jeroen and Gutiérrez, José María and Casewell, Nicholas R (2023) Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms. Nature Communications, 14 (1): 7812. pp. 1-15. ISSN 2041-1723
Ahmadi, Shirin and Pachis, Spyridon T and Kalogeropoulos, Konstantinos and McGeoghan, Farrell and Canbay, Vahap and Hall, Steven R and Crittenden, Edouard P and Dawson, Charlotte A and Bartlett, Keirah E and Gutiérrez, José María and Casewell, Nicholas R and Keller, Ulrich Auf dem and Laustsen, Andreas H (2022) Proteomics and histological assessment of an organotypic model of human skin following exposure to Naja nigricollis venom. Toxicon, 220: 106955. ISSN 0041-0101
McKeown, Brendan T and Relja, Nicholas J and Hall, Steven R and Gebremeskel, Simon and MacLeod, Jeanna M and Veinotte, Chansey J and Bennett, Leah G and Ohlund, Leanne B and Sleno, Lekha and Jakeman, David L and Berman, Jason N and Johnston, Brent and Goralski, Kerry B (2022) Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models. Canadian journal of physiology and pharmacology, 100 (11). pp. 1065-1076. ISSN 0008-4212
Menzies, Stefanie K and Litschka-Koen, Thea and Edge, Rebecca J and Alsolaiss, Jaffer and Crittenden, Edouard and Hall, Steven R and Westhorpe, Adam and Thomas, Brent and Murray, James and Shongwe, Nondusimo and Padidar, Sara and Lalloo, David G and Casewell, Nicholas R and Pons, Jonathan and Harrison, Robert A (2022) Two snakebite antivenoms have potential to reduce Eswatini's dependency upon a single, increasingly unavailable product : Results of preclinical efficacy testing. PLoS Neglected Tropical Diseases, 16 (9): e0010496. ISSN 1935-2727
Menzies, Stefanie K and Dawson, Charlotte A and Crittenden, Edouard and Edge, Rebecca J and Hall, Steven R and Alsolaiss, Jaffer and Wilkinson, Mark C and Casewell, Nicholas R and Harrison, Robert A and Ainsworth, Stuart (2022) Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition. Scientific Reports, 12 (1). p. 11328. ISSN 2045-2322
Alomran, Nessrin and Blundell, Patricia and Alsolaiss, Jaffer and Crittenden, Edouard and Ainsworth, Stuart and Dawson, Charlotte A and Edge, Rebecca J and Hall, Steven R and Harrison, Robert A and Wilkinson, Mark C and Menzies, Stefanie K and Casewell, Nicholas R (2022) Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms. Toxins, 14 (7): 443. ISSN 2072-6651
Kazandjian, Taline D and Hamilton, Brett R and Robinson, Samuel D and Hall, Steven R and Bartlett, Keirah E and Rowley, Paul and Wilkinson, Mark C and Casewell, Nicholas R and Undheim, Eivind A B (2022) Physiological constraints dictate toxin spatial heterogeneity in snake venom glands. BMC Biology, 20 (1): 148. ISSN 1741-7007
Menzies, Stefanie K and Clare, Rachel H and Xie, Chunfang and Westhorpe, Adam and Hall, Steven R and Edge, Rebecca J and Alsolaiss, Jaffer and Crittenden, Edouard and Marriott, Amy E and Harrison, Robert A and Kool, Jeroen and Casewell, Nicholas R (2022) In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus. Toxicon: X, 14. p. 100118. ISSN 2590-1710
Clare, Rachel H and Hall, Steven R and Patel, Rohit N and Casewell, Nicholas R (2021) Small Molecule Drug Discovery for Neglected Tropical Snakebite. Trends in Pharmacological Sciences, 42 (5). pp. 340-353. ISSN 0165-6147
Tomko, Andrea and O'Leary, Lauren and Trask, Hilary and Achenbach, John C and Hall, Steven R and Goralski, Kerry B and Ellis, Lee D and Dupré, Denis J (2019) Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer. Frontiers in Pharmacology, 10. p. 1124. ISSN 1663-9812
Forget, Stephanie M and Robertson, Andrew W and Hall, Steven R and MacLeod, Jeanna M and Overy, David P and Kerr, Russell G and Goralski, Kerry B and Jakeman, David L (2018) Isolation of a jadomycin incorporating L-ornithine, analysis of antimicrobial activity and jadomycin reactive oxygen species (ROS) generation in MDA-MB-231 breast cancer cells. The Journal of antibiotics, 71 (8). pp. 722-730. ISSN 0021-8820
Robertson, Andrew W and MacLeod, Jeanna M and MacIntyre, Logan W and Forget, Stephanie M and Hall, Steven R and Bennett, Leah G and Correa, Hebelin and Kerr, Russell G and Goralski, Kerry B and Jakeman, David L (2018) Post Polyketide Synthase Carbon-Carbon Bond Formation in Type-II PKS-Derived Natural Products from Streptomyces venezuelae. Journal of Organic Chemistry, 83 (4). pp. 1876-1890. ISSN 0022-3263
Hall, Steven R and Toulany, Jay and Bennett, Leah G and Martinez-Farina, Camilo F and Robertson, Andrew W and Jakeman, David L and Goralski, Kerry B (2017) Jadomycins Inhibit Type II Topoisomerases and Promote DNA Damage and Apoptosis in Multidrug-Resistant Triple-Negative Breast Cancer Cells. Journal of Pharmacology and Experimental Therapeutics, 363 (2). pp. 196-210. ISSN 0022-3565
Hall, Steven R and Blundon, Heather L and Ladda, Matthew A and Robertson, Andrew W and Martinez-Farina, Camilo F and Jakeman, David L and Goralski, Kerry B (2015) Jadomycin breast cancer cytotoxicity is mediated by a copper-dependent, reactive oxygen species-inducing mechanism. Pharmacology research & perspectives, 3 (2). e00110. ISSN 2052-1707
Issa, Mark E and Hall, Steven R and Dupuis, Stephanie N and Graham, Cathy L and Jakeman, David L and Goralski, Kerry B (2014) Jadomycins are cytotoxic to ABCB1-, ABCC1-, and ABCG2-overexpressing MCF7 breast cancer cells. Anti-Cancer Drugs, 25 (3). pp. 255-69. ISSN 0959-4973