Items where Author is "Benedetto, Alexandre"

Journal Article

Holland, Carol and Dravecz, Nikolett and Owens, Lauren and Benedetto, Alexandre and Dias, Irundika and Gow, Alan and Broughton, Susan (2024) Understanding exogenous factors and biological mechanisms for cognitive frailty : A multidisciplinary scoping review. Ageing Research Reviews, 101: 102461. ISSN 1568-1637

Zárate-Potes, Alejandra and Ali, Irtiqa and Ribeiro Camacho, Margarida and Brownless, Hayley and Benedetto, Alexandre (2022) Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions. Frontiers in Microbiology, 13: 853629. ISSN 1664-302X

Benedetto, Alexandre and Bambade, Timothée and Au, Catherine and Tullet, Jennifer M.A. and Monkhouse, Jennifer and Dang, Hairuo and Cetnar, Kalina and Chan, Brian and Cabreiro, Filipe and Gems, David (2019) New label-free automated survival assays reveal unexpected stress resistance patterns during C. elegans aging. Aging Cell, 18 (5): e12998. ISSN 1474-9718

Benedetto, Alexandre and Gems, David (2019) Autophagy promotes visceral aging in wild-type C. elegans. Autophagy, 15 (4). pp. 737-732. ISSN 1554-8627

Ezcurra, Marina and Benedetto, Alexandre and Sornda, Thanet and Gilliat, Ann F. and Au, Catherine and Zhang, Qifeng and van Schelt, Sophie and Petrache, Alexandra L. and Wang, Hongyuan and Guardia, Yila de la and Bar-Nun, Shoshana and Tyler, Eleanor and Wakelam, Michael J. and Gems, David (2018) Erratum : C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies (Current Biology (2018) 28(16) (2544–2556.e5), (S0960982218308261) (10.1016/j.cub.2018.06.035)). Current Biology, 28 (20). ISSN 0960-9822

Ezcurra, Marina and Benedetto, Alexandre and Sornda, Thanet and Gilliat, Ann F and Au, Catherine and Zhang, Qifeng and van Schelt, Sophie and Petrache, Alexandra L and Wang, Hongyuan and de la Guardia, Yila and Bar-Nun, Shoshana and Tyler, Eleanor and Wakelam, Michael J and Gems, David (2018) C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies. Current Biology, 28 (16). 2544-2556.e5. ISSN 0960-9822

Wang, Hongyuan and Zhao, Yuan and Ezcurra, Marina and Benedetto, Alexandre and Gilliat, Ann F. and Hellberg, Josephine and Ren, Ziyu and Galimov, Evgeniy R. and Athigapanich, Trin and Girstmair, Johannes and Telford, Maximilian J. and Dolphin, Colin T. and Zhang, Zhizhou and Gems, David (2018) A parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans. npj Aging and Mechanisms of Disease, 4 (1): 6. ISSN 2056-3973

Galimov, Evgeniy R. and Pryor, Rosina E. and Poole, Sarah E. and Benedetto, Alexandre and Pincus, Zachary and Gems, David (2018) Rigor mortis-like process during organismal death in c. elegans. Opera Medica et Physiologica, 4. p. 74. ISSN 2500-2287

Galimov, Evgeniy R and Pryor, Rosina E and Poole, Sarah E and Benedetto, Alexandre and Pincus, Zachary and Gems, David (2018) Coupling of Rigor Mortis and Intestinal Necrosis during C. elegans Organismal Death. Cell Reports, 22 (10). pp. 2730-2741. ISSN 2211-1247

Ezcurra, Marina and Benedetto, Alexandre and Sornda, Thanet and Gilliat, Ann and Au, Catherine and Zhang, Qifeng and van Schelt, Sophie and Petrache, Alexandra L and de la Guardia, Yila and Bar-Nun, Shoshana and Tyler, Eleonor and Wakelam, Michael J and Gems, David (2017) Autophagy-dependent gut-to-yolk biomass conversion generates visceral polymorbidity in aging C. elegans. Biorxiv.

Tullet, Jennifer M.a. and Green, James W. and Au, Catherine and Benedetto, Alexandre and Thompson, Maximillian A. and Clark, Emily and Gilliat, Ann F. and Young, Adelaide and Schmeisser, Kathrin and Gems, David (2017) The SKN-1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms. Aging Cell, 16 (5). pp. 1191-1194. ISSN 1474-9718

Wang, Hongyuan and Zhao, Yuan and Ezcurra, Marina and Gilliat, Ann F and Hellberg, Josephine and Benedetto, Alexandre and Athigapanich, Trin and Girstmair, Johannes and Telford, Max and Zhang, Zhizhou and Gems, David (2017) Monsters in the uterus : a parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans. Biorxiv.

Avila, Daiana Silva and Benedetto, Alexandre and Au, Catherine and Bornhorst, Julia and Aschner, Michael (2016) Involvement of heat shock proteins on Mn-induced toxicity in Caenorhabditis elegans. BMC Pharmacology and Toxicology, 17 (1): 54. ISSN 2050-6511

Kuriyama, Sei and Theveneau, Eric and Benedetto, Alexandre and Parsons, Maddy and Tanaka, Masamitsu and Charras, Guillaume and Kabla, Alexandre and Mayor, Roberto (2014) In vivo collective cell migration requires an LPAR2-dependent increase in tissue fluidity. Journal of Cell Biology, 206 (1). pp. 113-127. ISSN 0021-9525

Benedetto, Alexandre and Accetta, Giovanni and Fujita, Yasuyuki and Charras, Guillaume (2014) Spatiotemporal control of gene expression using microfluidics. Lab on a Chip, 14 (7). pp. 1336-1347. ISSN 1473-0197

Tullet, Jennifer M. A. and Araiz, Caroline and Sanders, Matthew J. and Au, Catherine and Benedetto, Alexandre and Papatheodorou, Irene and Clark, Emily and Schmeisser, Kathrin and Jones, Daniel and Schuster, Eugene F. and Thornton, Janet M. and Gems, David (2014) DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans. PLoS Genetics, 10 (2): e1004109. ISSN 1553-7390

Coburn, Cassandra and Allman, Erik and Mahanti, Parag and Benedetto, Alexandre and Cabreiro, Filipe and Pincus, Zachary and Matthijssens, Filip and Araiz, Caroline and Mandel, Abraham and Vlachos, Manolis and Edwards, Sally-Anne and Fischer, Grahame and Davidson, Alexander and Pryor, Rosina E and Stevens, Ailsa and Slack, Frank J and Tavernarakis, Nektarios and Braeckman, Bart P and Schroeder, Frank C and Nehrke, Keith and Gems, David (2013) Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans. Plos Biology, 11 (7): e1001613. ISSN 1544-9173

Avila, Daiana Silva and Benedetto, Alexandre and Au, Catherine and Manarin, Flávia and Erikson, Keith and Soares, Felix Antunes and Rocha, João Batista Teixeira and Aschner, Michael (2012) Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans by preventing oxidative stress. Free Radical Biology and Medicine, 52 (9). pp. 1903-1910. ISSN 0891-5849

Aitlhadj, Layla and Avila, Daiana Silva and Benedetto, Alexandre and Aschner, Michael and Stürzenbaum, Stephen Richard (2011) Environmental exposure, obesity, and Parkinson's disease : lessons from fat and old worms. Environmental Health Perspectives, 119 (1). pp. 20-28. ISSN 0091-6765

Exil, Vernat J. and Silva Avila, Daiana and Benedetto, Alexandre and Exil, Elizabeth A. and Adams, Margaret R. and Au, Catherine and Aschner, Michael (2010) Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans. PLoS ONE, 5 (12): e14228. ISSN 1932-6203

Benedetto, Alexandre and Au, Catherine and Avila, Daiana Silva and Milatovic, Dejan and Aschner, Michael (2010) Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans. PLoS Genetics, 6 (8). ISSN 1553-7390

Au, Catherine and Benedetto, Alexandre and Anderson, Joel and Labrousse, Arnaud and Erikson, Keith and Ewbank, Jonathan J. and Aschner, Michael (2009) SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans. PLoS ONE, 4 (11): e7792. ISSN 1932-6203

Benedetto, Alexandre and Au, Catherine and Aschner, Michael (2009) Manganese-induced dopaminergic neurodegeneration : insights into mechanisms and genetics shared with Parkinson's disease. Chemical Reviews, 109 (10). pp. 4862-4884. ISSN 0009-2665

Leung, Maxwell C. K. and Williams, Phillip L. and Benedetto, Alexandre and Au, Catherine and Helmcke, Kirsten J. and Aschner, Michael and Meyer, Joel N. (2008) Caenorhabditis elegans : an emerging model in biomedical and environmental toxicology. Toxicological sciences : an official journal of the Society of Toxicology, 106 (1). pp. 5-28. ISSN 1096-0929

McCaughan, Danny and Au, Catherine and Benedetto, Alexandre and Milatovic, Dejan and Aschner, Judy and Aschner, Michael (2008) Antioxidant properties of blirubin in the model organism, Caenorhabditis elegans. International Journal of Neuroprotection and Neuroregeneration, 4 (3). pp. 252-262. ISSN 1745-1183

Au, Catherine and Benedetto, Alexandre and Aschner, Michael (2008) Manganese transport in eukaryotes : the role of DMT1. NeuroToxicology, 29 (4). pp. 569-576. ISSN 0161-813X

Liégeois, Samuel and Benedetto, Alexandre and Michaux, Grégoire and Belliard, Guillaume and Labouesse, Michel (2007) Genes required for osmoregulation and apical secretion in Caenorhabditis elegans. Genetics, 175 (2). pp. 709-724. ISSN 0016-6731

Liégeois, Samuel and Benedetto, Alexandre and Garnier, Jean-Marie and Schwab, Yannick and Labouesse, Michel (2006) The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans. Journal of Cell Biology, 173 (6). pp. 949-961. ISSN 0021-9525

Bihl, Franck and Salez, Laurent and Beaubier, Magali and Torres, David and Larivière, Line and Laroche, Line and Benedetto, Alexandre and Martel, Dominic and Lapointe, Jean-Martin and Ryffel, Bernhard and Malo, Danielle (2003) Overexpression of toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice. Journal of Immunology, 170 (12). pp. 6141-6150. ISSN 0022-1767

Thesis

Ng, Tze Chang (Justin) and Broughton, Susan and Benedetto, Alexandre (2023) Introducing Commensal Bacteria from Caenorhabditis elegans to Drosophila melanogaster : Effects on Health, Ageing and Insulin-like Signalling. Masters thesis, Lancaster University.

Papatziamou, Dimitra and Robinson, Nick and Benedetto, Alexandre (2023) Investigating the Evolution of the Ubiquitin Proteasome System (UPS) and the Endosomal Sorting Complex Required for Transport (ESCRT) system in the archaea; novel insights from an uncultivated Asgard archaeon, Odinarchaeum yellowstonii LCB_4. PhD thesis, Lancaster University.

Hardgrave, Alex and Worthington, John and D'Elia, Riccardo and Rigby, Rachael and Benedetto, Alexandre (2023) Innate Immune Modulation by Fluoroquinolones : The Influence of Gastrointestinal Hormones. PhD thesis, Lancaster University.

Owens, Lauren and Parkin, Edward and Benedetto, Alexandre and Gaffney, Christopher and Dawson, Neil (2023) The Role of Fibrates and Soluble Amyloid Precursor Alpha in Alzheimer’s Disease and Longevity. PhD thesis, Lancaster University.

Martin, Jack and Benedetto, Alexandre and Parry, Jackie (2023) The role of the Kynurenine pathway in Caenorhabditis elegans gut bacterium interactions. PhD thesis, Lancaster University.

Steel, Christopher and Benedetto, Alexandre and Fielding, Andrew and Mort, Richard (2021) Investigating the thermosensitivity of cancer cell division dynamics : Toward cancer thermotherapies? Masters thesis, Lancaster University.

Griffin, Becky and Hardy, John and Benedetto, Alexandre (2020) Printing bioelectronics. Masters thesis, Lancaster University.

Kumordzi, Yasmine and Dillon, Roderick and Benedetto, Alexandre (2019) Investigation into the migration of Leishmania within Phlebotomine sand flies. PhD thesis, Lancaster University.

Benedetto, Alexandre (2007) Etude de l’exocytose à la membrane apicale des cellules épithéliales de Caenorhabditis elegans. PhD thesis, Universite de Strasbourg (UdS).