Items where Author is "Allsop, David"

Journal Article

Hammond, Jessica and Maher, Barbara A. and Gonet, Tomasz and Bautista, Francisco and Allsop, David (2022) Oxidative Stress, Cytotoxic and Inflammatory Effects of Urban Ultrafine Road-Deposited Dust from the UK and Mexico in Human Epithelial Lung (Calu-3) Cells. Antioxidants, 11 (9): 1814. ISSN 2076-3921

Hammond, Jessica and Maher, Barbara and Ahmed, Imad and Allsop, David (2021) Variation in the concentration and regional distribution of magnetic nanoparticles in human brains, with and without Alzheimer’s disease, from the UK. Scientific Reports, 11: 9363. ISSN 2045-2322

Paraskevaidi, Maria and Allsop, David and Karim, Salman and Martin, Francis and Crean, StJohn (2020) Diagnostic biomarkers for Alzheimer’s disease using non‐invasive specimens. Journal of Clinical Medicine, 9 (6): 1673. ISSN 2077-0383

Martin, Glen P and McDonald, Kathryn R and Allsop, David and Diggle, Peter J and Leroi, Iracema (2020) Apathy as a behavioural marker of cognitive impairment in Parkinson's disease : a longitudinal analysis. Journal of Neurology, 267 (1). pp. 214-227. ISSN 0340-5354

Kasai, Takashi and Kojima, Yuta and Ohmichi, Takuma and Tatebe, Harutsugu and Tsuji, Yukiko and Noto, Yu-ichi and Kitani-Morii, Fukiko and Shinomoto, Makiko and Allsop, David and Mizuno, Toshiki and Tokuda, Takahiko (2019) Combined use of CSF NfL and CSF TDP-43 improves diagnostic performance in ALS : A comprehensive analysis on diagnostic and prognostic significance of plasma and CSF NfL, TDP-43, and tau. Annals of Clinical and Translational Neurology, 6 (12). pp. 2489-2502. ISSN 2328-9503

Shinomoto, Makiko and Kasai, Takashi and Tatebe, Harutsugu and Kondo, Masaki and Ohmichi, Takuma and Morimoto, Masafumi and Chiyonobu, Tomohiro and Terada, Naoto and Allsop, David and Yokota, Isao and Mizuno, Toshiki and Tokuda, Takahiko (2019) Plasma neurofilament light chain : A potential prognostic biomarker of dementia in adult Down syndrome patients. PLoS ONE, 14 (4): e0211575. ISSN 1932-6203

Paraskevaidi, Maria and Morais, Camilo and Freitas, Daniel and Lima, Kassio and Mann, David and Allsop, David and Martin-Hirsch, Pierre and Martin, Francis L. (2018) Blood-based near-infrared spectroscopy for the rapid low-cost detection of Alzheimer’s disease. Analyst, 143 (24). pp. 5959-5964. ISSN 0003-2654

Ross, Callum and Taylor, Mark Neville and Fullwood, Nigel James and Allsop, David (2018) Liposome delivery systems for the treatment of Alzheimer’s disease. International Journal of Nanomedicine, 2018 (13). pp. 8507-8522. ISSN 1178-2013

Paraskevaidi, Maria and Morais, Camilo and Halliwell, D. and Mann, David and Allsop, David and Martin-Hirsch, Pierre and Martin, Francis L. (2018) Raman spectroscopy to diagnose Alzheimer's disease and dementia with Lewy bodies in blood. ACS Chemical Neuroscience, 9 (11). 2786–2794. ISSN 1948-7193

Allsop, David and Aggidis, Anthony and Fullwood, Nigel James and Taylor, Mark Neville and Foulds, Penelope and Vincent, Shoona and Dale, Mark (2018) Untangled - peptide-based inhibitors of tau aggregation as a potential treatment for Alzheimer's disease. Journal of Prevention of Alzheimer's Disease, 5 (Suppl ). S15-S16. ISSN 2426-0266

Obasse, Idira Christopher and Taylor, Mark Neville and Fullwood, Nigel James and Allsop, David (2017) Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes. Interface Focus, 7 (6): 20160127. ISSN 2042-8898

Kasai, Takashi and Tatebe, Harutsugu and Kondo, Masaki and Ishii, Ryotaro and Ohmichi, Takuma and Yeung, Wing Tung Esther and Morimoto, Masafumi and Chiyonobu, Tomohiro and Terada, Naoto and Allsop, David and Nakagawa, Masanori and Mizuno, Toshiki and Tokuda, Takahiko (2017) Increased levels of plasma total tau in adult Down syndrome. PLoS ONE, 12 (11): e0188802. ISSN 1932-6203

Allsop, David and Taylor, Mark Neville and Fullwood, Nigel James and Michael, Maria and Aggidis, Anthony and Vincent, Shoona and Dale, Mark (2017) A novel approach to the therapy of Alzheimer's disease based on peptide nanoliposome inhibitors of Aβ and tau aggregation. Journal of Prevention of Alzheimer's Disease, 4 (4). pp. 385-386. ISSN 2426-0266

Nouri Emamzadeh, Fatemeh and Allsop, David (2017) α-Synuclein interacts with lipoproteins in plasma. Journal of Molecular Neuroscience, 63 (2). pp. 165-172. ISSN 0895-8696

Paraskevaidi, Maria and Morais, Camilo and Lima, Kassio and Snowden, Julie and Saxon, Jennifer and Richardson, Anna and Jones, Mathew and Mann, David and Allsop, David and Martin-Hirsch, Pierre and Martin, Frank (2017) Differential diagnosis of Alzheimer’s disease using spectrochemical analysis of blood. Proceedings of the National Academy of Sciences of the United States of America, 114 (38). E7929–E7938. ISSN 0027-8424

Tatebe, Harutsugu and Kasai, Takashi and Ohmichi, Takuma and Kishi, Yasuke and Kakeya, Tomoshi and Waragai, Masaaki and Kondo, Masaki and Allsop, David and Tokuda, Takahiko (2017) Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer’s disease and Down syndrome. Molecular Neurodegeneration, 12 (63): 63. ISSN 1750-1326

Kasai, Takashi and Kondo, Masaki and Ishii, Ryotaro and Tanaka, Akihiro and Ataka, Suzuka and Shimada, Hiroyuki and Tomiyama, Takami and Mori, Hiroshi and Taylor, Mark Neville and Allsop, David and Nakagawa, Masanori and Mizuno, Toshiki and Tokuda, Takahiko (2017) Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease. PLoS ONE, 12 (4). ISSN 1932-6203

Castelletto, V. and Ryumin, P. and Cramer, R. and Hamley, Ian and Taylor, Mark Neville and Allsop, David and Reza, M. and Ruokolainen, J. and Arnold, T. and Hermida-Merino, D. and Garcia, C.I. and Leal, M.C. and Castaño, E. (2017) Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives. Scientific Reports, 7: 43637. ISSN 2045-2322

Pellegrino, S. and Tonali, N. and Erba, E. and Kaffy, J. and Taverna, M. and Contini, A. and Taylor, Mark Neville and Allsop, David and Gelmi, M. L. and Ongeri, S. (2017) ß-Hairpin mimics containing a piperidine-pyrrolidine scaffold modulate the ß-amyloid aggregation process preserving the monomer species. Chemical Science, 8 (2). pp. 1295-1302. ISSN 2041-6520

Gregori, Maria and Taylor, Mark Neville and Salvati, Elisa and Re, Francesca and Mancini, Simona and Balducci, Claudia and Forloni, Gianluigi and Zambelli, Vanessa and Sesana, Silvia and Michael, Maria and Michail, Christos and Kolosov, Oleg Victor and Tinker-Mill, Claire Louisa and Sherer, Mike and Harris, Stephen and Fullwood, Nigel James and Masserini, Massimo and Allsop, David (2017) Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer’s Aβ peptide. Nanomedicine: Nanotechnology, Biology, and Medicine, 13 (2). pp. 723-732. ISSN 1549-9642

Morris, Olivia and Gregory, J. and Kadirvel, M. and Henderson, Fiona and Blykers, A. and McMahon, Adam and Taylor, Mark Neville and Allsop, David and Allan, Stuart and Grigg, J. and Boutin, Herve and Prenant, Christian (2016) Development and automation of a novel [18F]Fprosthetic group, 2-[18F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide. Applied Radiation and Isotopes, 116. pp. 120-127. ISSN 0969-8043

Maher, Barbara Ann and Ahmed, Imad and Karloukovski, Vassil Vassilev and MacLaren, Donald and Foulds, Penelope and Allsop, David and Mann, David and Torres-Jardon, Ricardo and Calderon-Garciduenas, Lilian (2016) Magnetite pollution nanoparticles in the human brain. Proceedings of the National Academy of Sciences of the United States of America, 113 (39). pp. 10797-10801. ISSN 0027-8424

Nouri Emamzadeh, Fatemeh and Aojula, Harmesh and McHugh, Patrick and Allsop, David (2016) Effects of different isoforms of apoE on aggregation of the α- synuclein protein implicated in Parkinson's disease. Neuroscience Letters, 618. pp. 146-151. ISSN 0304-3940

Kaffy, Julia and Brinet, Dimitri and Soulier, Jean-Louis and Tonali, Nicolo and Fera, Katia Fabiana and Iacone, Yasmine and Hoffmann, Anais R. F. and Khemtemourian, Lucie and Crousse, Benoit and Taylor, Mark Neville and Allsop, David and Taverna, Myriam and Lequin, Olivier and Ongeri, Sandrine (2016) Designed glycopeptidomimetics disrupt protein−protein interactions mediating amyloid β‑peptide aggregation and restore neuroblastoma cell viability. Journal of Medicinal Chemistry, 59 (5). pp. 2025-2040. ISSN 0022-2623

Sherer, Mike and Fullwood, Nigel James and Taylor, Mark and Allsop, David (2015) A preliminary electron microscopic investigation into the interaction between Aβ1-42 peptide and a novel nanoliposome- coupled retro-inverso peptide inhibitor, developed as a potential treatment for Alzheimer's disease. Journal of Physics: Conference Series, 644 (1): 012040. ISSN 1742-6588

Allsop, David and Mayes, Jennifer (2014) Amyloid β-peptide and Alzheimer's disease. Essays in Biochemistry, 56: 7. pp. 99-110. ISSN 0071-1365

Mayes, Jennifer and Tinker-Mill, Claire and Kolosov, Oleg and Zhang, Hao and Tabner, Brian and Allsop, David (2014) Amyloid-β fibrils in Alzheimer's Disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species. Journal of Biological Chemistry, 289. pp. 12052-12062. ISSN 0021-9258

Tinker-Mill, Claire and Mayes, Jennifer and Allsop, David and Kolosov, Oleg (2014) Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation. Scientific Reports, 4: 4004.

Kasai, Takashi and Tokuda, Takahiko and Taylor, Mark and Kondo, Masaki and Mann, David M. A. and Foulds, Penny and Nakagawa, Masanori and Allsop, David (2013) Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples. Neuroscience Letters, 551. pp. 17-22. ISSN 0304-3940

Foulds, Penny and Diggle, Peter and Mitchell, John Douglas and Parker, Angela and Hasegawa, Masato and Masuda-Suzukake, Masami and Mann, David M. A. and Allsop, David (2013) A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson’s disease. Scientific Reports, 3: 2540.

Parthsarathy, Vadivel and McClean, Paula L and Hölscher, Christian and Taylor, Mark and Tinker, Claire and Jones, Glynn and Kolosov, Oleg and Salvati, Elisa and Gregori, Maria and Masserini, Massimo and Allsop, David (2013) A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's Disease. PLoS ONE, 8 (1): e54769. ISSN 1932-6203

Kasai, Takashi and Tokuda, Takahiko and Taylor, Mark and Nakagawa, Masanori and Allsop, David (2012) Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aß oligomers. Biochemical and Biophysical Research Communications, 422 (3). pp. 375-380. ISSN 0006-291X

Foulds, Penny and Yokota, O and Thurston, A and Davidson, Y and Ahmed, Z and Holton, J and Thompson, J C and Akiyama, H and Arai, T and Hasegawa, M and Gerhard, A and Allsop, David and Mann, D M A (2012) Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies. Neurobiology of Disease, 45 (1). pp. 188-195. ISSN 1095-953X

Foulds, Penny and Mann, David and Allsop, David (2012) Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease (Editorial). Expert Review of Molecular Diagnostics, 12 (2). pp. 115-117. ISSN 1473-7159

Davidson, Yvonne S and Raby, Samantha and Foulds, Penny and Robinson, Andrew and Thompson, Jennifer C and Sikkink, Stephen and Yusuf, Imran and Amin, Hanan and Duplessis, Daniel and Troakes, Claire and Al-Sarraj, Safa and Sloan, Carolyn and Esiri, Margaret M and Prasher, Vee P and Allsop, David and Neary, David and Pickering-Brown, Stuart M and Snowden, Julie S and Mann, David M A (2011) TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's Syndrome : association with age, hippocampal sclerosis and clinical phenotype. Acta Neuropathologica, 122 (6). pp. 703-713. ISSN 0001-6322

Taylor, Mark and Moore, Susan and Mourtas, Spyridon and Niarakis, Anna and Re, Francesca and Zona, Cristiano and La Ferla, Barbara and Nicotra, Francesco and Masserini, Massimo and Antimisiaris, Sophia G and Gregori, Maria and Allsop, David (2011) Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide. Nanomedicine: Nanotechnology, Biology, and Medicine, 7 (5). pp. 541-550.

Masad, Atef and Tabner, Brian J and Mayes, Jennifer and Allsop, David (2011) The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation. Free Radical Biology and Medicine, 51 (4). pp. 869-875. ISSN 1873-4596

Foulds, Penny and Mitchell, J Douglas and Parker, Angela and Turner, Roisin and Green, Gerwyn and Diggle, Peter and Hasegawa, Masato and Taylor, Mark and Mann, David and Allsop, David (2011) Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 25 (12). pp. 4127-4137. ISSN 0892-6638

Tabner, Brian J and Mayes, Jennifer and Allsop, David (2010) Hypothesis : soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease. International Journal of Alzheimer's Disease, 2011: 546380. ISSN 2090-0252

Foulds, Penny and Mann, David M A and Mitchell, J Douglas and Allsop, David (2010) Parkinson disease : progress towards a molecular biomarker for Parkinson disease. Nature Reviews Neurology, 6 (7). pp. 359-361. ISSN 1759-4766

Taylor, Mark and Moore, Susan and Mayes, Jennifer and Parkin, Edward and Beeg, Marten and Canovi, Mara and Gobbi, Marco and Mann, David M A and Allsop, David (2010) Development of a proteolytically stable retro-inverso peptide inhibitor of β-amyloid oligomerization as a potential novel treatment for Alzheimer's disease. Biochemistry, 49 (15). pp. 3261-3272. ISSN 1520-4995

Fukumoto, Hiroaki and Tokuda, Takahiko and Kasai, Takashi and Ishigami, Noriko and Hidaka, Hiroya and Kondo, Masaki and Allsop, David and Nakagawa, Masanori (2010) High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24 (8). pp. 2716-2726. ISSN 1530-6860

Matharu, Balpreet and Gibson, Gillian and Parsons, Richard and Huckerby, Thomas N and Moore, Susan A and Cooper, Leanne J and Millichamp, Robert and Allsop, David and Austen, Brian (2009) Galantamine inhibits β-amyloid aggregation and cytotoxicity. Journal of the Neurological Sciences, 280 (1-2). pp. 49-58.

Paleologou, Katerina E and Kragh, Christine L and Mann, David M A and Salem, Sultan A and Al-Shami, Rania and Allsop, David and Hassan, Ahmed H and Jensen, Poul H and El-Agnaf, Omar M A (2009) Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies. Brain, 132 (4). pp. 1093-1101. ISSN 1460-2156

Kasai, Takashi and Tokuda, Takahiko and Ishigami, Noriko and Sasayama, Hiroshi and Foulds, Penelope and Mitchell, Douglas J and Mann, David M A and Allsop, David and Nakagawa, Masanori (2009) Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathologica, 117 (1). pp. 55-62. ISSN 0001-6322

Foulds, Penny and Davidson, Yvonne and Mishra, Manjari and Hobson, David J and Humphreys, Kirsty M and Taylor, Mark and Johnson, Nancy and Weintraub, Sandra and Akiyama, Haruhiko and Arai, Tetsuaki and Hasegawa, Masato and Bigio, Eileen H and Benson, Fiona E and Allsop, David and Mann, David M A (2009) Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration. Acta Neuropathologica, 118 (5). pp. 647-658. ISSN 0001-6322

Austen, Brian M and Paleologou, Katerina E and Ali, Sumaya A E and Qureshi, Mohamed M and Allsop, David and El-Agnaf, Omar M A (2008) Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's β-amyloid peptide. Biochemistry, 47 (7). pp. 1984-1992. ISSN 0006-2960

Allsop, David and Mayes, Jennifer and Moore, Susan and Masad, Atef and Tabner, Brian J (2008) Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease. Biochemical Society Transactions, 36 (6). pp. 1293-1298. ISSN 1470-8752

Foulds, Penelope and McAuley, Erica and Gibbons, Linda and Davidson, Yvonne and Pickering-Brown, Stuart M and Neary, David and Snowden, Julie S and Allsop, David and Mann, David M A (2008) TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration. Acta Neuropathologica, 116 (2). pp. 141-146. ISSN 0001-6322

Salem, Sultan A and Allsop, David and Mann, David M A and Tokuda, Takahiko and El-Agnaf, Omar M A (2007) An investigation into the lipid-binding properties of α-, β- and γ-synucleins in human brain and cerebrospinal fluid. Experimental Brain Research, 1170. pp. 103-111. ISSN 1432-1106

Masad, Atef and Hayes, Lee and Tabner, Brian and Turnbull, Stuart and Cooper, Leanne and Fullwood, Nigel J. and German, Matthew and Kametani, Fuyuki and El-Agnaf, Omar M. A. and Allsop, David (2007) Copper-mediated formation of hydrogen peroxide from the amylin peptide : a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus? FEBS Letters, 581 (18). pp. 3489-3493. ISSN 0014-5793

Fullwood, Nigel J. and Hayashi, Yoshihito and Allsop, David (2006) Plasma amyloid-β concentrations in Alzheimer's disease : an alternative hypothesis. Lancet Neurology, 5 (12). pp. 1000-1001. ISSN 1474-4422

Tokuda, Takahiko and Salem, Sultan A. and Allsop, David and Mizuno, Toshiki and Nakagawa, Masanori and Qureshi, Mohamed M. and Locascio, Joseph J. and Schlossmacher, Michael G. and El-Agnaf, Omar (2006) Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson’s disease. Biochemical and Biophysical Research Communications, 349 (1). pp. 162-166. ISSN 0006-291X

Allsop, David and Martin, Frank and Moore, Susan and Fullwood, Nigel J. (2006) Donepezil for severe Alzheimer's disease. Lancet, 368 (9533). pp. 361-362. ISSN 1474-547X

Tabner, Brian J. and Turnbull, Stuart and King, Jennifer and Benson, Fiona E. and El-Agnaf, Omar M. A. and Allsop, David (2006) A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on β-amyloid and α-synuclein. Free Radical Research, 40 (7). pp. 731-739. ISSN 1071-5762

El-Agnaf, Omar M. A. and Salem, Sultan A. and Paleologou, Katerina E. and Curran, Martin D. and Gibson, Mark J. and Court, Jennifer A. and Schlossmacher, Michael G. and Allsop, David (2006) Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease. FASEB Journal, 20 (3). pp. 419-425. ISSN 1530-6860

Tabner, Brian J. and El-Agnaf, Omar M. A. and German, M. J. and Fullwood, Nigel J. and Allsop, David (2005) Protein aggregation, metals and oxidative stress in neurodegenerative diseases. Biochemical Society Transactions, 33 (5). pp. 1082-1086. ISSN 0300-5127

Tabner, Brian J. and El-Agnaf, Omar M. A. and Turnbull, Stuart and German, Matthew J. and Paleologou, Katerina E. and Hayashi, Yoshihito and Cooper, Leanne J. and Fullwood, Nigel and Allsop, David (2005) Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia. Journal of Biological Chemistry, 280 (43). pp. 35789-35792. ISSN 1083-351X

El-Agnaf, Omar M. A. and Paleologou, Katerina E. and Greer, Brett and Abogrein, Abdulmawala M. and King, Jennifer and Salem, Sultan A. and Fullwood, Nigel J. and Benson, Fiona E. and Hewitt, Rebecca and Ford, Kirstie J. and Martin, Frank and Harriott, Patrick and Cookson, Mark R. and Allsop, David (2004) A strategy for designing inhibitors of α-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders. FASEB Journal, 18 (11). pp. 1315-1317. ISSN 0892-6638

Moore, S. A. and Huckerby, T. N. and Gibson, G. L. and Fullwood, Nigel J. and Turnbull, Iain and Tabner, Brian J. and El-Agnaf, Omar M. A. and Allsop, David (2004) Both the D-(+) and L-(-) enantiomers of nicotine inhibit Aβ aggregation and cytotoxicity. Biochemistry, 43 (3). pp. 819-826. ISSN 0006-2960

Gibson, G. L. and Allsop, David and Austen, B. M. (2004) Induction of cellular oxidative stress by the β-amyloid peptide involved in Alzheimer's disease. Protein and Peptide Letters, 11 (3). pp. 257-270. ISSN 0929-8665

Martin, Frank and Allsop, David and Williamson, Sally J. M. and Paleologou, Katerina E. and El-Agnaf, Omar M. A. (2004) α-Synuclein and the pathogenesis of Parkinson’s disease. Protein and Peptide Letters, 11 (3). pp. 229-237. ISSN 0929-8665

Martin, Frank and Williamson, Sally J. M. and Paleologou, Katerina E. and Hewitt, R. and El-Agnaf, Omar M. A. and Allsop, David (2003) Fe(II)-induced DNA damage in α-synuclein-transfected human dopaminergic BE(2)-M17 neuroblastoma cells: detection by the Comet assay. Journal of Neurochemistry, 87 (3). pp. 620-630. ISSN 0022-3042

El-Agnaf, Omar M. A. and Salem, Sultan A. and Paleologou, Katerina E. and Cooper, Leanne J. and Fullwood, Nigel J. and Gibson, Mark J. and Curran, Martin D. and Court, Jennifer A. and Mann, David M. A. and Ikeda, Shu-Ichi and Cookson, Mark R. and Hardy, John and Allsop, David (2003) α-Synuclein implicated in Parkinson’s disease is present in extracellular biological fluids, including human plasma. FASEB Journal, 17 (13). pp. 1945-1947. ISSN 0892-6638

Turnbull, Stuart and Tabner, Brian J. and Brown, David R. and Allsop, David (2003) Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126. NeuroReport, 14 (13). pp. 1743-1745. ISSN 1473-558X

El-Agnaf, Omar M. A. and Walsh, Dominic M. and Allsop, David (2003) Soluble oligomers for the diagnosis of neurodegenerative diseases. Lancet Neurology, 2 (8). pp. 461-462. ISSN 1474-4422

Turnbull, Stuart and Tabner, Brian J. and Brown, David R. and Allsop, David (2003) Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231. Biochemistry, 42 (25). pp. 7675-7681. ISSN 0006-2960

Turnbull, Stuart and Tabner, Brian J. and Brown, David R. and Allsop, David (2003) Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126. Neuroscience Letters, 336 (3). pp. 159-162. ISSN 0304-3940

Tabner, Brian J. and Turnbull, Stuart and El-Agnaf, Omar M. A. and Allsop, David (2003) Direct production of reactive oxygen species from aggregating proteins and peptides implicated in the pathogenesis of neurodegenerative diseases. Current Medicinal Chemistry Immunology Endocrine and Metabolic Agents, 3 (4). pp. 299-308. ISSN 1568-0134

Tabner, Brian J. and Turnbull, Stuart and El-Agnaf, Omar M. A. and Allsop, David (2002) Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease. Free Radical Biology and Medicine, 32 (11). pp. 1076-1083. ISSN 0891-5849

Pickering-Brown, S. M. and Richardson, A. M. T. and Snowden, J. S. and McDonagh, A. and Burns, A. and Braudie, W. and Baker, M. and Yen, S.-H. and Hardy, J. and Hutton, M. and Davies, Y. and Allsop, David and Craufurd, D. and Neary, D. and Mann, D. M. A. (2002) Inherited frontotemporal dementia in 9 British families associated with intronic mutations in the tau gene. Brain, 125 (4). pp. 732-751. ISSN 1460-2156

Allsop, David and Swanson, Linda and Moore, Susan and Davies, Yvonne and York, Amber and El-Agnaf, Omar M. A. and Soutar, Ian (2001) Fluorescence anisotropy : a method for early detection of Alzheimer β-peptide (Aβ) aggregation. Biochemical and Biophysical Research Communications, 285 (1). pp. 58-63. ISSN 1090-2104

Turnbull, Stuart and Tabner, Brian J. and El-Agnaf, Omar M. A. and Twyman, Lance J. and Allsop, David (2001) New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps. Free Radical Biology and Medicine, 30 (10). pp. 1154-1162. ISSN 0891-5849

Turnbull, Stuart and Tabner, Brian J. and Moore, Susan and Davies, Yvonne and El-Agnaf, Omar M. A. and Allsop, David (2001) α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro. Free Radical Biology and Medicine, 30 (10). pp. 1163-1170. ISSN 0891-5849

Allsop, David and Gibson, Gillian and Martin, Ian K. and Moore, Susan and Turnbull, Stuart and Twyman, Lance J. (2001) 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran and 2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of β-amyloid peptide. Bioorganic and Medicinal Chemistry Letters, 11 (2). pp. 255-257. ISSN 0960-894X

Tabner, Brian J. and Turnbull, Stuart and El-Agnaf, Omar M. A. and Allsop, David (2001) Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. Current Topics in Medicinal Chemistry, 1. pp. 483-493. ISSN 1568-0266

Pickering-Brown, Stuart and Baker, Matt and Yen, Shu-Hui and Liu, Wan-Kyng and Hasegawa, Masato and Cairns, Nigel and Lantos, Peter L. and Rossor, Martin and Iwatsubo, Takeshi and Davies, Yvonne and Allsop, David and Furlong, Rob and Owen, Frank and Hardy, John and David Mann, David and Hutton, Mike (2000) Pick's disease is associated with mutations in the tau gene. Annals of Neurology, 48 (6). pp. 589-867. ISSN 0364-5134

Gardner, R. C. and Assinder, S. J. and Christie, G. and Mason, G. G. F. and Markwell, R. and Wadsworth, H. and McLaughlin, M. and King, R. and Chabot-Fletcher, M. C. and Breton, J. and Allsop, David and Rivett, A. J. (2000) Characterisation of peptidyl boronic acid inhibitors of mammalian 20S and 26S proteasomes and their inhibition of proteasomes in cultured cells. Biochemical Journal, 346. pp. 447-454. ISSN 0264-6021

Allsop, David and Twyman, Lance and Davies, Yvonne and Moore, Susan and York, Amber and Swanson, Linda and Soutar, Ian (2000) Modulation of β-amyloid production and fibrillisation. Biochemical Society Symposia, 67. pp. 1-14. ISSN 1744-1439

Twyman, Lance J. and Allsop, David (1999) A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran. Tetrahedron Letters, 40 (52). pp. 9383-9384. ISSN 0040-4039

Christie, G. and Markwell, R. E. and Gray, C. W. and Smith, L. and Godfrey, F. and Mansfield, F. and Wadsworth, H. and King, R. and McLaughlin, M. and Cooper, D. G. and Ward, R. V. and Howlett, D. R. and Hartmann, T. and Lichtenthaler, S. F. and Beyreuther, K. and Underwood, J. and Gribble, S. K. and Cappai, R. and Masters, C. L. and Tamaoka, A. and Gardner,, R. L. and Rivett, A. J. and Karran, E. H. and Allsop, David (1999) Alzheimer's Disease : correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome. Journal of Neurochemistry, 73 (1). pp. 195-204. ISSN 0022-3042

Howlett, D. R. and Ward, R. V. and Bresciani, L. and Jennings, K. H. and Christie, G. and Allsop, David and Gray, C. W. and Karran, E. H. (1999) Biological activity associated with a high molecular weight form of β-amyloid. Alzheimer's Reports, 2. pp. 171-177. ISSN 1461-6130

Contribution in Book/Report/Proceedings

Tabner, Brian and Moore, Susan and Mayes, Jennifer and Allsop, David (2013) A possible key role for redox-active metal ions and soluble oligomers in neurodegenerative diseases. In: Brain diseases and metalloproteins :. Pan Stanford, Boca Raton, Fla., pp. 11-32. ISBN 978-981-4316-01-9

Grishin, Ilja and Tinker, Claire and Allsop, David and Robson, Alex and Kolosov, Oleg (2012) Nanoscale SPM characterisation of nacre aragonite plates and synthetic human amyloid fibres. In: NSTI-Nanotech 2012 :. CRC PRESS-TAYLOR & FRANCIS GROUP, Santa Clara, USA, pp. 110-113. ISBN 9781466562745

Howlett, D. R. and Allsop, David and Karran, E. H. (2001) The biology and molecular neuropathology of β-amyloid protein. In: Neurobiology of Alzheimer's disease :. Oxford University Press, Oxford, pp. 75-102. ISBN 0198524595

Allsop, David (2000) Introduction to Alzheimer's disease. In: Alzheimer's disease : methods and protocols :. Humana Press, Totawa, New Jersey, pp. 1-21.

Evin, G. and Reed, G. and Tanner, J.E. and Li, Q.X. and Culvenor, J.G. and Fuller, S.J. and Wadsworth, H. and Allsop, David and Ward, R.V. and Karran, E.H. and Gray, C.W. and Hartmann, T. and Lichtenthaler, S.F. and Weidemann, A. and Beyreuther, K. and Masters, C.L. (1999) Characterization of an α-secretase candidate from human brain using a new western blot assay. In: Alzheimer's disease and related disorders :. Wiley, pp. 411-418.

Allsop, David and Christie, G. and Gray, C. and Holmes, S. and Markwell, R. and Owen, D. and Smith, L. and Wadsworth, H. and Ward, R.V. and Hartmann, T. and Lichtenthaler, S.F. and Evin, G. and Fuller, S. and Tanner, J. and Masters, C.L. and Beyreuther, K. and Roberts, G.W. (1997) Studies on inhibition of β-amyloid formation in APP-751-transfected IMR-32 cells, and SPA4CT-transfected SHSY5Y cells. In: Alzheimer's disease : biology, diagnosis and therapeutics. Wiley, New York, pp. 717-727.

Howlett, D.R. and James, S. and Allsop, David and Roberts, G.W. (1996) Mechanism of cerebral amyloidosis in Alzheimer's disease. In: Neurobiology of Alzheimer's disease :. BIOS Scientific Publishers, Oxford, pp. 46-59. ISBN 1872748147

Allsop, David and Clements, A. and Kennedy, H.E. and Walsh, D.M. and Williams, C.H. (1994) Mechanism of cerebral amyloidosis in Alzheimer's disease. In: Amyloid precursor protein in development, ageing and Alzheimer's disease :. Springer Verlag, Berlin, pp. 46-59.

Allsop, David and Kennedy, H.E. and Kametani, F. (1993) Secretory derivatives of Alzheimer amyloid precursor protein in cerebrospinal fluid and brain : only Kunitz-containing forms show amyloid immunoreactivity. In: Alzheimer's disease : advances in clinical and basic research. Wiley, Chichester, pp. 421-429.

Allsop, David and Yamamoto, T. and Kametani, F. and Miyazaki, N. and Ishii, T. (1991) High affinity amyloid peptide β/A4 binding sites and a putative "APP secretase" in rat brain. In: Proceedings of the XIth International Congress of Neuropathology : The Japanese Society of Neuropathology. Sasaki, Japan, pp. 119-127.

Allsop, David and Yamamoto, T. and Kametani, F. and Miyazaki, N. and Ishii, T. (1991) Studies on the binding and proteolytic cleavage of an Alzheimer amyloid synthetic peptide. In: Frontiers of Alzheimer research :. Elsevier, Amsterdam, pp. 171-183.

Ikeda, S.I. and Allsop, David (1990) Amyloid β-protein pathology (in Japanese). In: 1990 Annual Review of Neurology (in Japanese) :. Chugai Igaku Publishers, Tokyo, pp. 9-19.

Roberts, G.W. and Lofthouse, R. and Allsop, David and Landon, M. and Kidd, M. and Prusiner, S.B. and Crowe, T.J. (1990) Amyloids in neurodegenerative diseases : immunocytochemical studies. In: Proceedings of II International Symposium on Unconventional Viruses of the Central Nervous System :. UNSPECIFIED, Paris, pp. 602-616.

Allsop, David and Haga, S. and Haga, C. and Ishii, T. (1990) Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons : evidence for a neuronal origin of senile plaque amyloid. In: Molecular biology and genetics of Alzheimer disease :. Elsevier, Amsterdam, pp. 95-104.

Allsop, David and Haga, S. and Haga, C. and Ishii, T. (1990) Evidence for a neuronal origin of senile plaques in Down's syndrome brains. In: Basic and therapeutic aspects of Alzheimer's and Parkinson's diseases :. Plenum Press, New York, pp. 83-86.

Allsop, David and Ikeda, S.I. and Glenner, G.G. (1989) Evidence for the derivation of a peptide ligand from the amyloid β protein precursor of Alzheimer's disease. In: Alzheimer's disease and related disorders : proceedings of the First International Conference on Alzheimer's Disease and Related Disorders, held in Las Vegas, Nevada, September 5-9, 1988. Progress in clinical and biological research . Alan R. Liss, New York, pp. 893-902. ISBN 0845151673

Shoji, S and Maruyama, K. and Ikeda, S. and Yanagisawa, N. and Ishihara, T. and Allsop, David (1989) Immunohistochemical studies of cerebrovascular amyloid deposits in brains with cerebral amyloid angiopathy. In: 1988 Annual Report of the Primary Amyloidosis Research Committee :. The Ministry of Health and Welfare of Japan, pp. 27-30.

Ikeda, S.I. and Allsop, David and Glenner, G.G. (1989) A study of the morphology and distribution of amyloid β-protein immunoreactive plaque and related lesions in the brains of Alzheimer's disease and adult Down's syndrome. In: Alzheimer's disease and related disorders :. Alan R. Liss, New York, pp. 313-323.

Allsop, David and Roberts, G.W. and Landon, M. and Kidd, M. and Lowe, J.S. and Reynolds, G.P. and Crowe, T.J. (1987) Antibody staining of cerebral amyloid in Alzheimer’s disease, Down’s syndrome, Creutzfeldt-Jakob disease and Gerstmann-Straussler syndrome. In: Advancing Frontiers in Alzheimer’s Disease Research :. University of Texas Press, Austin, pp. 137-153.

Allsop, David (1986) Biochemistry of cerebral amyloid in Alzheimer’s disease, the unconventional slow virus diseases, and Icelandic cerebrovascular amyloidosis. In: Amyloidosis :. Martinus Nijhoff Publishers/ Brill Academic, Dordrecht, pp. 243-253.

Kidd, Michael and Allsop, David and Landon, Michael (1985) Senile plaque amyloid. In: Modern approaches to the dementias, part 1 : etiology and pathophysiology. Karger, Basel, pp. 114-126.

Atkinson, Y.E. and Allsop, David and Bradbeer, J.W. (1981) Chloroplast development in normal and mutant lines of barley. In: Photosynthesis V : chloroplast development. Balaban International Science Services, Philadelphia, pp. 797-808.

Allsop, David and Atkinson, Y.E. and Bradbeer, J.W. (1981) The effect of a high non-permissive temperature on chloroplast development in barley. In: Photosynthesis V : chloroplast development. Balaban International Science Services, Philadelphia, pp. 787-795.

Contribution to Conference

Kolosov, Oleg and Tovee, Peter and Tinker-Mill, Claire and Allsop, David (2014) Nanomechanical and nanothermal mapping of initial stages of amyloid fibres formation. In: Bristol Nanoscience Symposium 2014, 2014-09-15 - 2014-09-16, UK.

Thesis

Marshall, Toby and Benson, Fiona and Parkin, Edward and Fullwood, Nigel and Allsop, David (2024) Purification of the neurodegenerative disease associated protein TDP-43 and development of TDP-43 aggregation inhibitors. PhD thesis, Lancaster University.

Hammond, Jessica and Allsop, David and Parkin, Edward (2023) Air pollution, nanotoxicity and neurodegeneration; exploring the relationship between environmental metallic nanoparticles and human health. PhD thesis, Lancaster University.

Ross, Callum and Allsop, David and Fullwood, Nigel (2020) The development of antibody loaded liposomes for the treatment of Alzheimer's Disease. Masters thesis, Lancaster University.

Aggidis, Anthony and Allsop, David (2019) The development of peptide-based inhibitors for Tau aggregation as a potential therapeutic for Alzheimer’s disease. PhD thesis, Lancaster University.

Obasse, Idira Christopher and Allsop, David and Parkin, Edward (2017) Developing peptide-based inhibitors of amylin aggregation as a novel treatment for type 2 diabetes. PhD thesis, Lancaster University.

Michael, Maria and Allsop, David and Holscher, Christian (2017) A study investigating the blood-brain barrier penetration, distribution and elimination of retro-inverso peptides as candidate treatments for Alzheimer’s disease. PhD thesis, Lancaster University.

Sherer, Mike and Allsop, David and Fullwood, Nigel (2016) Recombinant production of Aβ1-42 peptide and analysis of interactions between Aβ1-42 and Peptide Inhibitor NanoParticles (PINPs) developed as a potential novel treatment for Alzheimer’s Disease. Masters thesis, Lancaster University.

Ismail, Kurimun and Allsop, David (2016) Development and utilization of Luminex biomarker assays for diagnosis and monitoring of neurodegenerative disease. PhD thesis, Lancaster University.

Michail, Christos and Allsop, David (2015) Development of peptide inhibitor nanoparticles (PINPs) for treatment of Alzheimer’s Disease. Masters thesis, Lancaster University.

Tinker-Mill, Claire and Allsop, David and Kolosov, Oleg (2015) Nanoscale imaging and characterisation of Amyloid-β. PhD thesis, Lancaster University.