Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans

Knight, Jo and Gardner, G. T. and Clark, A. J. and Caulfield, M. J. (2000) Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans. Journal of Human Hypertension, 14 (6). pp. 385-387. ISSN 0950-9240

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Abstract

Essential hypertension is a major risk factor for cardiovascular disease in humans, and originates from both genetic and environmental factors. Data from animal and more recently human studies have indicated the presence of a gene influencing blood pressure on human chromosome 17. This study tested for linkage of markers located on chromosome 17q to essential hypertension in African Caribbean hypertensive families. No support of linkage was found between the markers studied and hypertension, however only genes of a lamda sib value of less than 1.8 could be excluded.

Item Type:
Journal Article
Journal or Publication Title:
Journal of Human Hypertension
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2700/2724
Subjects:
?? africaafrican continental ancestry groupcaribbean regionchromosome mappingchromosomes, human, pair 17cohort studiesgenetic linkagehumanshypertensioninternal medicine ??
ID Code:
79899
Deposited By:
Deposited On:
07 Jun 2016 15:50
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 16:06