Peptide-directed assembly of functional supramolecular polymers for biomedical applications: electroactive molecular tongue-twisters (oligoalanine-oligoaniline-oligoalanine) for electrochemically enhanced drug delivery

Hardy, John G. and Amend, Megan N. and Geissler, Sydney and Lynch, Vincent M. and Schmidt, Christine E. (2015) Peptide-directed assembly of functional supramolecular polymers for biomedical applications: electroactive molecular tongue-twisters (oligoalanine-oligoaniline-oligoalanine) for electrochemically enhanced drug delivery. Journal of Materials Chemistry B, 3 (25). pp. 5005-5009. ISSN 2050-750X

[thumbnail of c5tb00106d-supplementary-information-open-access]

Preview

PDF (c5tb00106d-supplementary-information-open-access)
c5tb00106d_si_open_access.pdf - Published Version
Available under License Creative Commons Attribution.
Download (671kB)

[thumbnail of c5tb00106d_post_print_open_access]

Preview

PDF (c5tb00106d_post_print_open_access)
c5tb00106d_open_access.pdf - Published Version
Available under License Creative Commons Attribution.
Download (1MB)

Abstract

We report the preparation and characterization of films of electroactive supramolecular polymers based on non-electroactive oligoalanines and electroactive oligoanilines. Fibroblasts adhered to and proliferated on the films, and the delivery of the clinically relevant anti-inflammatory drug dexamethasone phosphate could be enhanced upon the application of an electrical stimulus.

Item Type:

Journal Article

Journal or Publication Title:

Journal of Materials Chemistry B

Additional Information:

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. This journal is © The Royal Society of Chemistry 2015

Uncontrolled Keywords:

/dk/atira/pure/subjectarea/asjc/2200/2204

Subjects:

?? supramolecular chemistrysupramolecular polymersbiomaterialsdrug deliverychemistry (miscellaneous)biomaterialsbiomedical engineeringmaterials science(all)medicine(all)chemistry(all)sdg 3 - good health and well-being ??

ID Code:

75392

Deposited By:

ep_importer_pure

Deposited On:

09 Sep 2015 06:32

Refereed?:

Yes

Published?:

Published

Last Modified:

31 Dec 2023 00:35

URI:

https://eprints.lancs.ac.uk/id/eprint/75392