Kerns, Jemma G. and Gikas, Panagiotis D. and Buckley, Kevin and Shepperd, Adam and Birch, Helen L. and McCarthy, Ian and Miles, Jonathan and Briggs, Timothy W. R. and Keen, Richard and Parker, Anthony W. and Matousek, Pavel and Goodship, Allen E. (2014) Evidence from Raman spectroscopy of a putative link between inherent bone matrix chemistry and degenerative joint disease. Arthritis and Rheumatology, 66 (5). pp. 1237-1246. ISSN 2326-5191
Full text not available from this repository.Abstract
Osteoarthritis (OA) is a common debilitating disease that results in degeneration of cartilage and bone in the synovial joints. Subtle changes in the molecular structure of the subchondral bone matrix occur and may be associated with cartilage changes. The aim of this study was to explore whether the abnormal molecular changes observed in the matrix of OA subchondral bone can be identified with Raman spectroscopy.