In situ high-energy X-ray diffraction study of a bioactive calcium silicate foam immersed in simulated body fluid

FitzGerald, V. and Drake, K. O. and Jones, J. R. and Smith, Mark E. and Honkimaeki, V. and Buslaps, T. and Kretzschmer, M. and Newport, R. J. (2007) In situ high-energy X-ray diffraction study of a bioactive calcium silicate foam immersed in simulated body fluid. Journal of Synchrotron Radiation, 14 (6). pp. 492-499. ISSN 1600-5775

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Abstract

The method of in situ time-resolved high-energy X-ray diffraction, using the intrinsically highly collimated X-ray beam generated by the European Synchrotron Radiation Facility, is demonstrated. A specially designed cell, which allows the addition of liquid components, has been used to study the reaction mechanisms of a foamed bioactive calcia-silica sol-gel glass immersed in simulated body fluid. Analysis of the X-ray diffraction data from this experiment provides atomic distances, via the pair correlation functions, at different stages of the dissolution of the glass and of the associated calcium phosphate, and ultimately hydroxyapatite, i.e. bone mineral, formation. Hence, changes in the atomic scale structure can be analysed as a function of reaction time, giving an insight into the evolution of the structure of both the glass matrix and the hydroxyapatite surface growth.

Item Type:
Journal Article
Journal or Publication Title:
Journal of Synchrotron Radiation
Uncontrolled Keywords:
/dk/atira/pure/core/keywords/physics
Subjects:
?? high-energy x-ray diffraction, glass structure, bioactive glass, in situ diffractionphysicsinstrumentationnuclear and high energy physicsradiation ??
Departments:
ID Code:
52873
Deposited By:
Deposited On:
29 Feb 2012 11:59
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 12:41