Computation of the asymptotic null distribution of goodness-of-fit tests for multi-state models.

Titman, Andrew C. (2009) Computation of the asymptotic null distribution of goodness-of-fit tests for multi-state models. Lifetime Data Analysis, 15 (4). pp. 519-533. ISSN 1380-7870

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Abstract

We develop an improved approximation to the asymptotic null distribution of the goodness-of-fit tests for panel observed multi-state Markov models (Aguirre-Hernandez and Farewell, Stat Med 21:1899-1911, 2002) and hidden Markov models (Titman and Sharples, Stat Med 27:2177-2195, 2008). By considering the joint distribution of the grouped observed transition counts and the maximum likelihood estimate of the parameter vector it is shown that the distribution can be expressed as a weighted sum of independent X^2_1 random variables, where the weights are dependent on the true parameters. The performance of this approximation for finite sample sizes and where the weights are calculated using the maximum likelihood estimates of the parameters is considered through simulation. In the scenarios considered, the approximation performs well and is a substantial improvement over the simple X^2_1 approximation.

Item Type:
Journal Article
Journal or Publication Title:
Lifetime Data Analysis
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2600/2604
Subjects:
?? multi-state model - goodness-of-fit - panel observation - hidden markov modelapplied mathematicsgeneral medicinemedicine(all)qa mathematics ??
ID Code:
23532
Deposited By:
Deposited On:
28 Jan 2009 14:00
Refereed?:
Yes
Published?:
Published
Last Modified:
25 Nov 2024 01:09