Radde, Nicole and Bar, Nadav S. and Banaji, Murad (2010) Graphical methods for analysing feedback in biological networks – A survey. International Journal of Systems Science, 41 (1). pp. 35-46. ISSN 0020-7721
Full text not available from this repository.Abstract
Observed phenotypes usually arise from complex networks of interacting cell components. Qualitative information about the structure of these networks is often available, while quantitative information may be partial or absent. It is natural then to ask what, if anything, we can learn about the behaviour of the system solely from its qualitative structure. In this article we review some techniques which can be applied to answer this question, focussing in particular on approaches involving graphical representations of model structure. By applying these techniques to various cellular network examples, we discuss their strengths and limitations, and point to future research directions.