Socio-economic determinants for reduced uptake of routine childhood vaccination in Afghanistan

Saeedzai, Sayed Ataullah and Knight, Jo and Filipe, Luis and Moore, Sam and Loevinsohn, Benjamin (2025) Socio-economic determinants for reduced uptake of routine childhood vaccination in Afghanistan. Global Health Action, 18 (1): 2582262. ISSN 1654-9716

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Abstract

Background : Coverage of many routine childhood vaccinations in Afghanistan is low and declining. For instance, only 60% of eligible children received doses of the pentavalent vaccine in 2013–18, and this fell to 51% in 2022/23. Objective : To help explain the underlying causes behind this trend, this study aims to identify socio-demographic factors relating to caregivers whose children are either entirely unvaccinated or only partially vaccinated. Method : A secondary analysis of Multi Indictor Cluster survey (MICS) 2022/23 data was conducted that focused on the level of vaccination children had received by the time they reach their first birthday. Children were categorized into unvaccinated, under-vaccinated, and fully vaccinated groups and binary and multinomial logistic regression models were fitted with household characteristics included as explanatory variables. Results : The study data comprised 6,178 children aged 12–23 months with a predominance of rural areas (76.2%). In the multinomial analysis, children from Pashto-speaking households had significantly higher odds of being unvaccinated (OR = 3.54, 95% CI: 2.62–4.79) and under-vaccinated (OR = 2.19, 95% CI: 1.74–2.75) compared with those who were fully vaccinated. Maternal education was found to be highly significant, with children whose mothers had no formal education found to be more likely to be under vaccinated (69.1% unvaccinated/under-vaccinated) compared to those with primary education (41.9% unvaccinated/under-vaccinated, adjusted odds ratio: 0.59. 95% CI: 0.43–0.81). Children from the richest households had a full vaccination rate of 55.9% and were less likely to be unvaccinated than fully vaccinated (adjusted odds ratio: 0.22, 95% CI: 0.14–0.35). Conclusion : Full vaccination coverage is low, with approximately one-third of Afghan children aged 12–23 months receiving complete vaccine schedules. However, this study shows that rates vary significantly with a range of cultural, economic, and educational factors. These findings suggest that improving maternal healthcare access and education, along with focused outreach in specific demographic groups, may be effective in enhancing immunization coverage.