Donnelly, R. F. and Fletcher, N. C. and McCague, P. J. and Donnelly, J. and McCarron, P. A. and Tunney, M. M. (2007) Design, synthesis and Photodynamic antimicrobial activity of ruthenium trischelate diimine complexes. Letters in Drug Design and Discovery, 4 (3). pp. 175-179. ISSN 1570-1808
Full text not available from this repository.Abstract
In this study, we describe, for the first time, the synthesis and photophysical and microbiological investigation of ruthenium trischelate diimine complexes designed so as to possess properties specifically suited for use in Photodynamic antimicrobial chemotherapy (PACT). Of the three compounds investigated, one ([Ru(dmob)3]Cl2) has demonstrated considerable promise as a photosensitiser for use in PACT. As a result, this compound is now the subject of comprehensive chemical, toxicological and formulation studies.