Alonso, José Miguel and Muñoz, Maria Paz (2018) Heterobimetallic catalysis: Platinum-gold-catalyzed tandem cyclization/C−X coupling reaction of (hetero)arylallenes with nucleophiles. Angewandte Chemie International Edition, 57 (17). pp. 4742-4746. ISSN 1433-7851
Full text not available from this repository.Abstract
Heterobimetallic catalysis offers new opportunities for reactivity and selectivity but still presents challenges, and only a few metal combinations have been explored so far. Reported here is a Pt‐Au heterobimetallic catalyst system for the synthesis of a family of multi‐heteroaromatic structures through tandem cyclization/C−X coupling reaction. Au‐catalyzed 6‐endo‐cyclization takes place as the first fast step. Pt‐Au clusters are proposed to be responsible for the increased reactivity in the second step, that is, the intermolecular nucleophilic addition which occurs through an outer‐sphere mechanism by hybrid homogeneous‐heterogeneous catalysis.