Studying pharmaceutical tablets mixing process inside a perforated pan-coater using in-line terahertz sensing

Li, Xiaoran and Bawuah, Prince and Williams, Bryan M. and Zeitler, J. Axel and Lin, Hungyen (2021) Studying pharmaceutical tablets mixing process inside a perforated pan-coater using in-line terahertz sensing. In: 2020 45th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2020 :. International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz . IEEE Computer Society Press, USA, pp. 754-755. ISBN 9781728166209

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Abstract

In-line terahertz sensing has been demonstrated to measure the coating thickness of individual pharmaceutical tablets during coating operation. As coating uniformity is highly dependent on tablet mixing, this study presents our research progress to date on using in-line terahertz sensing to investigate the effects of baffle design, drum rotational speed and batch size, on tablet mixing inside a laboratory-sized perforated pan coater.