An overview of the use of biomaterials, nanotechnology, and stem cells for detection and treatment of COVID-19 : towards a framework to address future global pandemics

Ghaffari, Maryam and Moztarzadeh, Fathollah and Mollazadeh-Bajestani, Maryam and Uludağ, Hasan and Hardy, John and Mozafari, Masoud (2021) An overview of the use of biomaterials, nanotechnology, and stem cells for detection and treatment of COVID-19 : towards a framework to address future global pandemics. Emergent Materials, 4. 19–34. ISSN 2522-574X

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Abstract

A novel SARS-like coronavirus (severe acute respiratory syndrome-related coronavirus-2, SARS-CoV-2) outbreak has recently become a worldwide pandemic. Researchers from various disciplinary backgrounds (social to natural science, health and medicine, etc.) have studied different aspects of the pandemic. The current situation has revealed how the ongoing development of nanotechnology and nanomedicine can accelerate the fight against the novel viruses. A comprehensive solution to this and future pandemic outbreaks includes preventing the spread of the virus through anti-viral personal protective equipment (PPE) and anti-viral surfaces, plus efforts to encourage behavior to minimize risks. Studies of previously introduced anti-viral biomaterials and their optimization to fight against SARS-CoV-2 is the foundation of most of the recent progress. The identification of non-symptomatic patients and symptomatic patients is vital. Reviewing published research highlights the pivotal roles of nanotechnology and biomaterials in the development and efficiency of detection techniques, e.g., by applying nanotechnology and nanomedicine as part of the road map in the treatment of coronavirus disease 2019 (COVID-19) patients. In this review, we discuss efforts to deploy nanotechnology, biomaterials, and stem cells in each step of the fight against SARS-CoV-2, which may provide a framework for future efforts in combating global pandemics.