Biocompatibility testing of aluminium and zirconium based hybrid organic-inorganic materials

Balciunas, Evaldas and Baldock, Sara and Hardy, John and Baltriukiene, Daiva (2016) Biocompatibility testing of aluminium and zirconium based hybrid organic-inorganic materials. In: Laboratory Animals in Research, 2016-11-24 - 2016-11-25.

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Abstract

Introduction: Tissue engineering is a field based on the idea that the majority of human tissues and organs can be replaced by autologous artificial tissues, composed of cells and scaffolds [1]. There are many scaffold fabrication techniques, but one of the most promising ones is laser multiphoton polymerisation [2]. A wide range of materials can be structured via this technique, but hybrid organic-inorganic materials are among the most widely investigated due to their high structuring quality and ease of workflow [3]. Here, we present an aluminium-based hybrid organic-inorganic material that is relatively simple to prepare, tune and structure in 3D. We investigate its biocompatibility by comparing it to a hybrid organic-inorganic material based on zirconium and a commercially available OrmoComp (Micro Resist Technology GmbH). [1] L. G. Cima et al,1991. DOI: 10.1115/1.2891228 [2] S. Maruo et al, 1997. DOI: 10.1364/OL.22.000132 [3] M. Farsari et al, 2010. DOI: 10.1088/2040-8978/12/12/124001 [4] M. Mailnauskas et al, 2012. DOI: 10.1007/s00339-012-6965-8