Lau, Sophie and Griffin, John and Hughes, Eleri and Middleton, David (2019) Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR. Chemical Communications, 55 (88). pp. 13287-13290. ISSN 1359-7345
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Abstract
NMR measurements of 19F chemical shift anisotropy and 1H-19F dipolar couplings provide unprecedented information on the molecular orientations of two fluorine-containing statin drugs within the heterogeneous environment of reconstituted high-density lipoprotein (rHDL) nanoparticles, a drug delivery system under clinical investigation.
Item Type:
Journal Article
Journal or Publication Title:
Chemical Communications
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2500/2505
Subjects:
?? materials chemistrysurfaces, coatings and filmsmetals and alloysceramics and compositesgeneral chemistrycatalysiselectronic, optical and magnetic materialschemistry(all) ??
ID Code:
137863
Deposited By:
Deposited On:
14 Oct 2019 13:39
Refereed?:
Yes
Published?:
Published
Last Modified:
28 Aug 2024 23:50