Accelerated acquisition in pure-shift spectra based on prior knowledge from 1H NMR

Shchukina, Alexandra and Kaźmierczak, Magdalena and Kasprzak, Paweł and Davy, Matthew and Akien, Geoffrey and Butts, Craig and Kazimierczuk, Krzysztof (2019) Accelerated acquisition in pure-shift spectra based on prior knowledge from 1H NMR. Chemical Communications, 55 (64). pp. 9563-9566. ISSN 1359-7345

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Abstract

Pure-shift NMR enhances the spectral resolution, but the optimal resolutions can only be obtained at the cost of the acquisition time. We propose to accelerate the acquisition using optimised ’burst’ non-uniform sampling schemes[I. E. Ndukwe, A. Shchukina, K. Kazimierczuk, C. P. Butts,ChemComm, 2016, 52, 12769] and then reconstructing the undersampled signal mathematically. Here, we focus on the reliability of this reconstruction depending on the sampling scheme and present a workflow for the sampling optimization. It is ready to be implemented in routine measurements and yields a great improvement of the reconstruction in challenging cases.