The mineralization effect on chitosan hydrogel structure containing collagen and alkaline phosphatase

Skwarczynska, Agata L. and Binias, Dorota and Maniukiewicz, Waldemar and Modrzejewska, Zofia and Douglas, Timothy E.L. (2019) The mineralization effect on chitosan hydrogel structure containing collagen and alkaline phosphatase. Journal of Molecular Structure, 1187. pp. 86-97. ISSN 0022-2860

[thumbnail of MOLSTRUC-D-18-03618R1 (1)]
Text (MOLSTRUC-D-18-03618R1 (1))
MOLSTRUC_D_18_03618R1_1_.pdf - Accepted Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (2MB)


Introducing collagen the basic ingredient of bone tissue into the structure of chitosan gels that are formed at physiological body temperature, aims to create so-called biomimetic structures, which are close in composition to the natural composition of bone tissue. The aim of this study was to determine the influence of mineralization on the structural properties of thermosensitive chitosan-collagen gels containing alkaline phosphatase (ALP) by SEM, XRD FTIR and XPS analyses, compared to the previously presented structure of chitosan-collagen gels before mineralization.

Item Type:
Journal Article
Journal or Publication Title:
Journal of Molecular Structure
Additional Information:
This is the author’s version of a work that was accepted for publication in Journal of Molecular Structure. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Molecular Structure, 1187, 2019 DOI: 10.1016/j.molstruc.2019.03.034
Uncontrolled Keywords:
ID Code:
Deposited By:
Deposited On:
22 Jun 2019 09:05
Last Modified:
18 Sep 2023 01:33