New insights into the bonding arrangements of L- and D-glutamates from solid state 17 O NMR

Lemaitre, V. and Pike, K.J. and Watts, A. and Anupold, T. and Samoson, A. and Smith, M.E. and Dupree, R. (2003) New insights into the bonding arrangements of L- and D-glutamates from solid state 17 O NMR. Chemical Physics Letters, 371 (1-2). pp. 91-97. ISSN 0009-2614

Abstract

Magic angle spinning (MAS) from L- and D-glutamic acid-HCl at 14.1 T produces highly structured and very similar NMR spectra. Lines from all 4 oxygen sites are readily distinguished and assigned. These 17O NMR spectra are very different from the previously reported 17O spectrum of the D,L-form presumably because that was a racemic crystal. 17O NMR from L-monosodium glutamate-HCl is very different again requiring the application of double angle rotation and 3 quantum MAS NMR to provide resolution of 5 different sites. Hence high resolution 17O solid state NMR techniques offer possible new insight into biochemical bonding processes. © 2003 Elsevier Science B.V. All rights reserved.