Lea, P. J. and Chen, Z.-H. and Leegood, R. C. and Walker, R. P. (2001) Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism? Amino Acids, 20 (3). pp. 225-241. ISSN 0939-4451
Full text not available from this repository.Abstract
Phosphoenolpyruvate carboxykinase (PEPCK) catalyses the reversible decarboxylation of oxaloacetate to yield phosphoenolpyruvate and CO2. The role of the enzyme in gluconeogenesis and anaplerotic reactions in a range of organisms is discussed, along with the important function in C4 and CAM photosynthesis in higher plants. In addition, new data are presented indicating that PEPCK may play a key role in amino acid metabolism. It is proposed that PEPCK is involved in the conversion of the carbon skeleton of asparagine/aspartate (oxaloacetate) to that of glutamate/glutamine (2-oxoglutarate). This metabolism is particularly important in the transport system, seeds and fruits of higher plants.
| Item Type: | Article |
|---|---|
| Journal or Publication Title: | Amino Acids |
| Uncontrolled Keywords: | Amino acid metabolism - Asparagine - Glutamate - Higher plants - Oxaloacetate - Phosphoenolpyruvate carboxykinase |
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Departments: | Faculty of Science and Technology > Lancaster Environment Centre |
| ID Code: | 10800 |
| Deposited By: | Mr Richard Ingham |
| Deposited On: | 24 Jul 2008 11:58 |
| Refereed?: | Yes |
| Published?: | Published |
| Last Modified: | 18 Sep 2013 15:58 |
| Identification Number: | |
| URI: | http://eprints.lancs.ac.uk/id/eprint/10800 |
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