Items where Department is "Biomedical & Life Sciences" and Year is 2001

Alfalah, Marwan and Parkin, Edward T. and Jacob, Ralf and Sturrock, Edward D. and Mentele, Reinhard and Turner, Anthony J. and Hooper, Nigel M. and Naim, Hassan Y. (2001) A Point Mutation in the Juxtamembrane Stalk of Human Angiotensin I-converting Enzyme Invokes the Action of a Distinct Secretase. Journal of Biological Chemistry, 276 (24). pp. 21105-21109. ISSN 1083-351X

Allinson, Sarah L. and Dianova, Irina I. and Dianov, Grigory L. (2001) DNA polymerase B is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts. EMBO Journal, 20 (23). pp. 6919-6926. ISSN 0261-4189

Allsop, David and Gibson, Gillian and Martin, Ian K. and Moore, Susan and Turnbull, Stuart and Twyman, Lance J. (2001) 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran and 2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of β-amyloid peptide. Bioorganic and Medicinal Chemistry Letters, 11 (2). pp. 255-257. ISSN 0960-894X

Allsop, David and Swanson, Linda and Moore, Susan and Davies, Yvonne and York, Amber and El-Agnaf, Omar M. A. and Soutar, Ian (2001) Fluorescence anisotropy:a method for early detection of Alzheimer β-peptide (Aβ) aggregation. Biochemical and Biophysical Research Communications, 285 (1). pp. 58-63. ISSN 1090-2104

Ban, Y and Koizumi, N and Fullwood, N J and Cooper, L and Nakamura, T and Inoki, K and Tsuzuki, M and Quantock, A J and Kinoshita, S (2001) Comparison of the ultrastructure and barrier function of cultivated human corneal epithelial cells on amniotic membrane with and without air-lifting. Investigative Ophthalmology and Visual Science, 42 (4). S267-S267. ISSN 0146-0404

Bee, A and Culley, F J and Alkhalife, I S and Bodman-Smith, K B and Raynes, J G and Bates, P A (2001) Transformation of Leishmania mexicana metacyclic promastigotes to amastigote-like forms mediated by binding of human C-reactive protein. Parasitology, 122 (5). pp. 521-529. ISSN 0031-1820

Bell, Sally J and Rigby, R and English, N and Mann, S D and Knight, S C and Kamm, M A and Stagg, A J (2001) Migration and maturation of human colonic dendritic cells. Journal of Immunology, 166 (8). pp. 4958-4967. ISSN 0022-1767

Bentley, J. and Walker, I. and McIntosh, E. and Whetton, Anthony D. and Owen-Lynch, P. Jane and Baldwin, S. A. (2001) Glucose transport regulation by p210 Bcr-Abl in a chronic myeloid leukaemia model. British Journal of Haematology, 112 (1). pp. 212-215. ISSN 0007-1048

Bibb, Lindsay C. and Holt, James K. L. and Tarttelin, Emma E. and Hodges, Matt and Gregory-Evans, Kevin and Rutherford, Adam and Lucas, Robert J. and Sowden, Jane C. and Gregory-Evans, Cheryl Y. (2001) Temporal and spatial expression patterns of the CRX gene and its downstream targets:critical differences during human and mouse eye development. Human Molecular Genetics, 10 (15). pp. 1571-1579. ISSN 1460-2083

Bolden, Kelle and Fullwood, N and Nieduszynski, I and Bairaktaris, G (2001) Localization of TRAMP (Tyrosine-Rich Acidic Matrix Protein). FASEB Journal, 15 (5). A893-A893. ISSN 0892-6638

Cheeseman, M T and Bates, P A and Crampton, J M (2001) Preliminary characterisation of esterase and platelet-activating factor (PAF)-acetylhydrolase activities from cat flea (Ctenocephalides felis) salivary glands. Insect Biochemistry and Molecular Biology, 31 (2). pp. 157-164. ISSN 0965-1748

Clancy, D. J. and Gems, D. and Harshman, L. G. and Oldham, S. and Stocker, H. and Hafen, E. and Leevers, S. J. and Partridge, L. (2001) Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science, 292 (5514). pp. 104-106.

Clancy, David J. and Kennington, W. Jason (2001) A simple method to achieve consistent larval density in bottle cultures. Drosophila Information Service, 84. pp. 168-169.

Draper, C. E. and Owen-Lynch, P. Jane and Bannister, C. M. and Miyan, J. (2001) Proliferation of cerebral cortical cells from the hydrocephalic HTx rat : an in vitro study. European Journal of Pediatric Surgery, 11 (S1). S51-S52. ISSN 0939-7248

English, J. and Pickup, R. and Parry, Jackie D. (2001) The potential harbouring of coliform bacteria by protozoa in biofilms. In: Biofilm community interactions : chance or necessity? Bioline, Cardiff, pp. 271-279.

Ginger, Michael L. and Billett, David S. M. and Mackenzie, Karen L. and Kiriakoulakis, Konstandinos and Neto, Renato R. and Boardman, Daniel K. and Santos, Vera L. C. S. and Horsfall, Ian M. and Wolff, George A. (2001) Organic matter assimilation and selective feeding by holothurians in the deep sea: some observations and comments. Progress in Oceanography, 50 (1-4). pp. 407-421. ISSN 0079-6611

Ginger, Michael L. and Chance, Michael L. and Sadler, Ian H. and Goad, L. John (2001) The Biosynthetic Incorporation of the Intact Leucine Skeleton into Sterol by the Trypanosomatid Leishmania mexicana. Journal of Biological Chemistry, 276 (15). pp. 11674-11682. ISSN 1083-351X

Heaton, K. and Drinkall, J. and Minett, A. and Hunt, A. P. and Parry, Jackie D. (2001) Amoeboid grazing on surface-associated prey. In: Biofilm community interactions : chance or necessity? Bioline, Cardiff, pp. 293-301.

Hodges, Matt and Gregory-Evans, C. (2001) Characterisation of the CRX Gene; Identification of Alternatively Spliced 5’ Exons and 3’ Sequence. In: New insights into retinal degenerative diseases. Kluwer Academic Publishers, USA, pp. 71-86. ISBN 0-306-46679-1

Howlett, D. R. and Allsop, David and Karran, E. H. (2001) The biology and molecular neuropathology of β-amyloid protein. In: Neurobiology of Alzheimer's disease. Oxford University Press, Oxford, pp. 75-102. ISBN 0198524595

Huckerby, Thomas N. and Brown, Gavin M. and Lauder, Robert M. and Nieduszynski, Ian A. (2001) Keratan sulfates : structural investigations using NMR spectroscopy. Abstracts of Papers of the American Chemical Society, 221 (2). p. 396. ISSN 0065-7727

Huckerby, Thomas N. and Brown, Gavin M. and Lauder, Robert M. and Nieduszynski, Ian A. (2001) Keratan sulfates : structural investigations using NMR spectroscopy. ACS Polymer Preprints, 42 (1). pp. 78-79.

Huckerby, Thomas N. and Lauder, Robert M. and Brown, Gavin M. and Nieduszynski, Ian A. and Anderson, Karen and Boocock, Joanne and Sandall, Patricia L. and Weeks, Stephen D. (2001) Characterisation of oligosaccharides from the chondroitin sulfates. 1H-NMR and 13C-NMR studies of reduced disaccharides and tetrasaccharides. European Journal of Biochemistry, 268 (5). pp. 1181-1189. ISSN 0014-2956

Hunt, A. P. and Hamilton-Taylor, John and Parry, Jackie D. (2001) The interactions between trace metals and epilithic biofilms in small acidic mountain streams. Archiv für Hydrobiologie, 153. pp. 155-176.

Kneupfer, Ellen and Stierhof, Y. D. and McKean, Paul G. and Smith, Deborah F. (2001) Characterisation of a differentially expressed protein that shows an unusual localisation to intracellular membranes in Leishmania major. Biochemical Journal, 356 (2). pp. 335-344. ISSN 0264-6021

Koizumi, N and Cooper, L and Fullwood, N J and Nakamura, T and Inoki, K and Tsuzuki, M and Kinoshita, S (2001) An evaluation of cultivated corneal limbal epithelial cells using cell suspension culture. Investigative Ophthalmology and Visual Science, 42 (4). S302-S302. ISSN 0146-0404

Lauder, R. M. and Huckerby, T. N. and Brown, Gavin and Bayliss, M. T. and Nieduszynski, I. A. (2001) Age-related changes in the sulphation of the chondroitin sulphate linkage region from human articular cartilage aggrecan. Biochemical Journal, 358 (2). pp. 523-528. ISSN 0264-6021

Masson, J. Y. and Stasiak, A. Z. and Stasiak, A. and Benson, Fiona E. and West, S. C. (2001) Complex formation by the human RAD51C and XRCC3 recombination repair proteins. Proceedings of the National Academy of Sciences of the United States of America, 98 (15). pp. 8440-8446. ISSN 0027-8424

Masson, J. Y. and Tarsounas, M. C. and Stasiak, A. Z. and Stasiak, A. and Shah, R. and McIlwraith, M. J. and Benson, Fiona E. and West, S. C. (2001) Identification and purification of two distinct complexes containing the five RAD51paralogs. Genes and Development, 15 (24). pp. 3296-3307. ISSN 0890-9369

Maughan, J and Dawson, R and Rimmer, S and Neil, S M and Fullwood, N and Ebdon, J (2001) Block amphiphilic networks. Abstracts of Papers of the American Chemical Society, 222. U377-U377. ISSN 0065-7727

McKean, P. G. and Keen, J. G. and Smith, D. F. and Benson, Fiona E. (2001) Identification and characterisation of a RAD51 gene from Leishmania major. Molecular and Biochemical Parasitology, 115 (2). pp. 209-216. ISSN 0166-6851

McKean, Paul G. and Denny, Paul W. and Kneupfer, Ellen and Keen, Jane K. and Smith, Deborah F. (2001) Phenotypic changes associated with deletion and over-expression of a stage-regulated gene family in Leishmania. Cellular Microbiology, 3 (8). pp. 511-523. ISSN 1462-5814

McKean, Paul G. and Vaughan, Sue and Gull, Keith (2001) The extended tubulin superfamily. Journal of Cell Science, 114 (15). pp. 2723-2733. ISSN 0021-9533

Meek, K. M. and Fullwood, Nigel J. (2001) Corneal and scleral collagens—a microscopist’s perspective. Micron, 32 (3). pp. 261-272. ISSN 0968-4328

Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (2001) Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase. Biochemical Journal, 358 (1). pp. 209-216. ISSN 0264-6021

Parry, Jackie D. and Heaton, Karen and Drinkall, Janice and Jones, Harriet L. J. (2001) The feasibility of using GFP-expressing Escherichia coli, coupled with fluorimetry, to determine protozoan ingestion rates. FEMS Microbiology Ecology, 35 (1). pp. 11-17. ISSN 0168-6496

Parry, Jackie D. and Hunt, A. P. and Drinkall, Janice and Heaton, Karen (2001) The influence of free-living protozoa on aquatic biofilm dynamics. In: Biofilm community interactions : chance or necessity? Bioline, Cardiff, pp. 255-261.

Qazi, Saara N. A. and Counil, Emilie and Morrissey, Julie and Rees, Catherine E. D. and Cockayne, Alan and Winzer, Klaus and Chan, Weng C. and Williams, Paul and Hill, Philip J. (2001) agr Expression Precedes Escape of Internalized Staphylococcus aureus from the Host Endosome. Infection and Immunity, 69 (11). pp. 7074-7082. ISSN 0019-9567

Rimmer, S and Haigh, R and Maughan, J and Tatersall, P and Fullwood, N and MacNeil, S and Dawson, R and Ebdon, J (2001) Amphiphilic networks:synthesis and biological properties. Abstracts of Papers of the American Chemical Society, 222. U345-U346. ISSN 0065-7727

Roberts, Stephen K. and Dixon, Graham K. and Fischer, Marc and Sanders, Dale (2001) A Novel Low-Affinity H⁺-Cl⁻ Co-Transporter in Yeast: Characterization by Patch Clamp. Mycologia, 93 (4). pp. 636-633. ISSN 0027-5514

Segal, Robert A. (2001) Eliade, Mircea. In: International encyclopedia of social and behavioural sciences. Elsevier, Amsterdam, pp. 4406-4409.

Segal, Robert A. (2001) Myth in religion. In: International encyclopedia of social and behavioural sciences. Elsevier, Amsterdam, pp. 10273-10278.

Sugita, Jiro and Yokoi, Norihiko and Fullwood, Nigel J. and Quantock, Andrew J. and Takada, Yoko and Nakamura, Yo and Kinoshita, Shigeru (2001) The Detection of Bacteria and Bacterial Biofilms in Punctal Plug Holes. Cornea, 20 (4). pp. 362-365. ISSN 0277-3740

Tabner, Brian J. and Turnbull, Stuart and El-Agnaf, Omar M. A. and Allsop, David (2001) Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. Current Topics in Medicinal Chemistry, 1. pp. 483-493. ISSN 1568-0266

Thaw, Paul and Baxter, Nicola J. and Hounslow, Andrea M. and Price, Clive and Waltho, Jonathan P. and Craven, C. Jeremy (2001) Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones. Nature Structural and Molecular Biology, 8 (8). pp. 701-704. ISSN 1545-9993

Turnbull, Stuart and Tabner, Brian J. and El-Agnaf, Omar M. A. and Twyman, Lance J. and Allsop, David (2001) New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps. Free Radical Biology and Medicine, 30 (10). pp. 1154-1162. ISSN 0891-5849

Turnbull, Stuart and Tabner, Brian J. and Moore, Susan and Davies, Yvonne and El-Agnaf, Omar M. A. and Allsop, David (2001) α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro. Free Radical Biology and Medicine, 30 (10). pp. 1163-1170. ISSN 0891-5849

Weaver, Sean A. and Russo, Maria Pia and Wright, Karen L. and Kolios, George and Jobin, Christian and Robertson, Duncan A. F. and Ward, Stephen G. (2001) Regulatory role of phosphatidylinositol 3-kinase on TNF-α-induced cyclooxygenase 2 expression in colonic epithelial cells. Gastroenterology, 120 (5). pp. 1117-1127. ISSN 0016-5085

Winzer, Klaus and Williams, Paul (2001) Quorum sensing and the regulation of virulence gene expression in pathogenic bacteria. International Journal of Medical Microbiology, 291 (2). pp. 131-143. ISSN 1438-4221

Xenaki, D and Gray, A and Downes, C P and Owen-Lynch, P J (2001) A novel tool for the detection of phosphatidylinositol-(3,4,5)-trisphosphate in primitive hematopoietic stem cells: Characterization of the response to IL-3 and Bcr-Abl. Blood, 98 (11). 290A-291A. ISSN 0006-4971

Xenaki, D. and Gray, A. and Downes, C. P. and Owen-Lynch, P. Jane (2001) A novel tool for the detection of phosphatidylinositol-(3,4,5)-trisphosphate in primitive hematopoietic stem cells : characterisation of the response to IL-3 and Bcr-Abl. Blood, 98 (11). 290A-291A. ISSN 0006-4971