Items where Author is "Thygesen, Helene"

Journal Article

Thygesen, Helene and Dragalin, Vlad and Whitehead, Anne and Whitehead, John (2012) A bivariate Bayesian dose-finding procedure applied to a seamless phase I/II trial in rheumatoid arthritis. Pharmaceutical Statistics, 11 (6). pp. 476-484. ISSN 1539-1604

Whitehead, John and Thygesen, Helene and Jaki, Thomas and Davis, S. and Halford, S. and Turner, H. and Cook, N. and Jodrell, Duncan (2012) A novel phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer. Statistics in Medicine, 31 (18). pp. 1931-1943. ISSN 1097-0258

Whitehead, John and Thygesen, Helene and Whitehead, Anne (2011) Bayesian procedures for phase I/II clinical trials investigating the safety and efficacy of drug combinations. Statistics in Medicine, 30 (16). pp. 1952-1970. ISSN 1097-0258

Whitehead, John and Thygesen, Helene and Whitehead, Anne (2010) A Bayesian dose-escalation procedure for phase I clinical trials based only on the assumption of monotonicity. Statistics in Medicine, 29 (17). pp. 1808-1824. ISSN 1097-0258

Whitehead, John and Kelly, Patrick and Zhou, Yinghui and Stallard, Nigel and Thygesen, Helene and Bowman, Clive (2009) Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme. Pharmaceutical Statistics, 8 (4). pp. 287-300. ISSN 1539-1604