Items where Author is "Smith, Terry K."

Zacharova, Marija K. and Tulloch, Lindsay B. and Gould, Eoin R. and Fraser, Andrew L. and King, Elizabeth F. and Menzies, Stefanie K. and Smith, Terry K. and Florence, Gordon J. (2019) Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase. European Journal of Organic Chemistry, 2019 (31-32). pp. 5434-5440. ISSN 1434-193X

Fraser, Andrew L. and Menzies, Stefanie K. and King, Elizabeth F.B. and Tulloch, Lindsay B. and Gould, Eoin R. and Zacharova, Marija K. and Smith, Terry K. and Florence, Gordon J. (2018) Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors. ACS Infectious Diseases, 4 (4). pp. 560-567. ISSN 2373-8227

Menzies, Stefanie K. and Tulloch, Lindsay B. and Florence, Gordon J. and Smith, Terry K. (2018) The trypanosome alternative oxidase : A potential drug target? Parasitology, 145 (2). pp. 175-183. ISSN 0031-1820

Tulloch, Lindsay B. and Menzies, Stefanie K. and Coron, Ross P. and Florence, Gordon J. and Smith, Terry K. (2018) Direct and indirect approaches to identify drug modes of action. IUBMB Life, 70 (1). pp. 9-22. ISSN 1521-6543

Gould, Eoin R. and King, Elizabeth F.B. and Menzies, Stefanie K. and Fraser, Andrew L. and Tulloch, Lindsay B. and Zacharova, Marija K. and Smith, Terry K. and Florence, Gordon J. (2017) Simplifying nature : Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins. Bioorganic and Medicinal Chemistry, 25 (22). pp. 6126-6136. ISSN 0968-0896

Tulloch, Lindsay B. and Menzies, Stefanie K. and Fraser, Andrew L. and Gould, Eoin R. and King, Elizabeth F. and Zacharova, Marija K. and Florence, Gordon J. and Smith, Terry K. (2017) Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues. PLoS Neglected Tropical Diseases, 11 (9): e0005886. ISSN 1935-2727

Florence, Gordon J. and Fraser, Andrew L. and Gould, Eoin R. and King, Elizabeth F. and Menzies, Stefanie K. and Morris, Joanne C. and Thomson, Marie I. and Tulloch, Lindsay B. and Zacharova, Marija K. and Smith, Terry K. (2016) Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors. ChemMedChem, 11 (14). pp. 1503-1506. ISSN 1860-7179

Shameer, Sanu and Logan-Klumpler, Flora J. and Vinson, Florence and Cottret, Ludovic and Merlet, Benjamin and Achcar, Fiona and Boshart, Michael and Berriman, Matthew and Breitling, Rainer and Bringaud, Frédéric and Bütikofer, Peter and Cattanach, Amy M. and Bannerman-Chukualim, Bridget and Creek, Darren J. and Crouch, Kathryn and de Koning, Harry P. and Denise, Hubert and Ebikeme, Charles and Fairlamb, Alan H. and Ferguson, Michael A. J. and Ginger, Michael L. and Hertz-Fowler, Christiane and Kerkhoven, Eduard J. and Mäser, Pascal and Michels, Paul A. M. and Nayak, Archana and Nes, David W. and Nolan, Derek P. and Olsen, Christian and Silva-Franco, Fatima and Smith, Terry K. and Taylor, Martin C. and Tielens, Aloysius G. M. and Urbaniak, Michael D. and van Hellemond, Jaap J. and Vincent, Isabel M. and Wilkinson, Shane R. and Wyllie, Susan and Opperdoes, Fred R. and Barrett, Michael P. and Jourdan, Fabien (2015) TrypanoCyc : a community-led biochemical pathways database for Trypanosoma brucei. Nucleic Acids Research, 43 (D1). D637-D644. ISSN 0305-1048

Florence, Gordon J. and Fraser, Andrew L. and Gould, Eoin R. and King, Elizabeth F.B. and Menzies, Stefanie K. and Morris, Joanne C. and Tulloch, Lindsay B. and Smith, Terry K. (2014) Non-natural Acetogenin Analogues as Potent Trypanosoma brucei Inhibitors. ChemMedChem, 9 (11). pp. 2548-2556. ISSN 1860-7179

Urbaniak, Michael D. and Crossman, Arthur and Chang, Tunhan and Smith, Terry K. and van Aalten, Daan M. F. and Ferguson, Michael A. J. (2005) The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme. Journal of Biological Chemistry, 280 (24). pp. 22831-22838. ISSN 0021-9258