Items where Author is "Owens, Lauren"
Holland, Carol and Dravecz, Nikolett and Owens, Lauren and Benedetto, Alexandre and Dias, Irundika and Gow, Alan and Broughton, Susan (2024) Understanding exogenous factors and biological mechanisms for cognitive frailty : A multidisciplinary scoping review. Ageing Research Reviews, 101: 102461. ISSN 1568-1637
Owens, Lauren and Parkin, Edward and Benedetto, Alexandre and Gaffney, Christopher and Dawson, Neil (2023) The Role of Fibrates and Soluble Amyloid Precursor Alpha in Alzheimer’s Disease and Longevity. PhD thesis, Lancaster University.
Owens, Lauren and Bracewell, Joshua and Benedetto, Alex and Dawson, Neil and Gaffney, Christopher and Parkin, Edward (2022) BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation : Beta Prime-Mediated Competitive Depletion of sAβPPα. Journal of Alzheimer's Disease, 86 (3). pp. 1201-1220. ISSN 1387-2877
Parkin, Edward T and Hammond, Jessica E and Owens, Lauren and Hodges, Matthew D (2022) The orphan drug dichloroacetate reduces amyloid beta-peptide production whilst promoting non-amyloidogenic proteolysis of the amyloid precursor protein. PLoS ONE, 17 (1): e0255715. ISSN 1932-6203
Owens, Lauren and Benedetto, Alex and Dawson, Neil and Gaffney, Christopher and Parkin, Edward (2021) Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer's disease. Brain Research, 1753: 147264. ISSN 0006-8993