Items where Author is "Mozgunov, Pavel"

Journal Article

Daniells, Libby and Mozgunov, Pavel and Barnett, Helen and Bedding, Alun and Jaki, Thomas (2025) How to Add Baskets to an Ongoing Basket Trial with Information Borrowing. Statistical Methods in Medical Research. ISSN 0962-2802

Jaki, Thomas and Barnett, Helen and Titman, Andrew and Mozgunov, Pavel (2024) A Seamless Phase I/II Platform Design with a Time-To-Event Efficacy Endpoint for Potential COVID-19 Therapies. Statistical Methods in Medical Research, 33 (11-12). pp. 2115-2130. ISSN 0962-2802

Greenstreet, Peter and Jaki, Thomas and Bedding, Alun and Harbron, Chris and Mozgunov, Pavel (2024) A multi‐arm multistage platform design that allows preplanned addition of arms while still controlling the family‐wise error. Statistics in Medicine, 43 (19). pp. 3613-3632. ISSN 0277-6715

Barnett, Helen and George, Matthew and Skanji, Donia and Saint-Hilary, Gaelle and Jaki, Thomas and Mozgunov, Pavel (2024) A Comparison of Model-Free Phase I Dose Escalation Designs for Dual-Agent Combination Therapies. Statistical Methods in Medical Research, 33 (2). pp. 203-226. ISSN 0962-2802

Daniells, Libby and Mozgunov, Pavel and Bedding, Alun and Jaki, Thomas (2023) A comparison of Bayesian information borrowing methods in basket trials and a novel proposal of modified exchangeability‐nonexchangeability method. Statistics in Medicine. ISSN 0277-6715

Serra, Alessandra and Mozgunov, Pavel and Jaki, Thomas (2023) A Bayesian multi‐arm multi‐stage clinical trial design incorporating information about treatment ordering. Statistics in Medicine, 42 (16). pp. 2841-2854. ISSN 0277-6715

Mozgunov, Pavel and Jaki, Thomas and Gounaris, Ioannis and Goddemeier, Thomas and Victor, Anja and Grinberg, Marianna (2022) Practical implementation of the partial ordering continual reassessment method in a Phase I combination‐schedule dose‐finding trial. Stat. Med., 41 (30). pp. 5789-5809. ISSN 0277-6715

Mozgunov, Pavel and Paoletti, Xavier and Jaki, Thomas (2022) A Benchmark for Dose Finding Studies with Unknown Ordering. Biostatistics, 23 (3). pp. 721-737. ISSN 1465-4644

Serra, Alessandra and Mozgunov, Pavel and Jaki, Thomas and Rigat, Fabio (2022) What is the expected benefit of patient-centric clinical development in oncology? Journal of Biopharmaceutical Statistics, 32 (3). pp. 414-426. ISSN 1054-3406

Menzies, Tom and Saint-Hilary, Gaelle and Mozgunov, Pavel (2022) A comparison of various aggregation functions in multi-criteria decision analysis for drug benefit–risk assessment. Statistical Methods in Medical Research, 31 (5). pp. 899-916. ISSN 0962-2802

Khoo, Saye H and Fitzgerald, Richard and Fletcher, Thomas and Ewings, Sean and Jaki, Thomas and Lyon, Rebecca and Downs, Nichola and Walker, Lauren and Tansley-Hancock, Olana and Greenhalf, William and Woods, Christie and Reynolds, Helen and Marwood, Ellice and Mozgunov, Pavel and Adams, Emily and Bullock, Katie and Holman, Wayne and Bula, Marcin D and Gibney, Jennifer L and Saunders, Geoffrey and Corkhill, Andrea and Hale, Colin and Thorne, Kerensa and Chiong, Justin and Condie, Susannah and Pertinez, Henry and Painter, Wendy and Wrixon, Emma and Johnson, Lucy and Yeats, Sara and Mallard, Kim and Radford, Mike and Fines, Keira and Shaw, Victoria and Owen, Andrew and Lalloo, David G and Jacobs, Michael and Griffiths, Gareth (2021) Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2 : a Phase I, open-label, dose-escalating, randomized controlled study. Journal of Antimicrobial Chemotherapy, 76 (12). pp. 3286-3295. ISSN 0305-7453

Desai, Yasin and Jaki, Thomas and Beresford, Michael W and Burnett, Thomas and Eleftheriou, Despina and Jacobe, Heidi and Leone, Valentina and Li, Suzanne and Mozgunov, Pavel and Ramanan, Athimalaipet V and Torok, Kathryn S and Anderson, Marina E and Anton, Jordi and Avcin, Tadej and Felton, Jessie and Foeldvari, Ivan and Laguda, Bisola and McErlane, Flora and Shaw, Lindsay and Zulian, Francesco and Pain, Clare E (2021) Prior elicitation of the efficacy and tolerability of Methotrexate and Mycophenolate Mofetil in Juvenile Localised Scleroderma. AMRC Open Research, 3. p. 20. ISSN 2517-6900

Kasianova, Ksenia and Kelbert, Mark and Mozgunov, Pavel (2021) Response adaptive designs for Phase II trials with binary endpoint based on context-dependent information measures. Computational Statistics and Data Analysis, 158: 107187. ISSN 0167-9473

Mozgunov, Pavel and Knight, Rochelle and Barnett, Helen and Jaki, Thomas (2021) Using an Interaction Parameter in Model-Based Phase I Trials for Combination Treatments? : A Simulation Study. International Journal of Environmental Research and Public Health, 18 (1): 345. ISSN 1660-4601

Mozgunov, Pavel and Jaki, Thomas Friedrich (2020) An information-theoretic approach for selecting arms in clinical trials. Journal of the Royal Statistical Society: Series B (Statistical Methodology), 82 (5). pp. 1223-1247. ISSN 1369-7412

Mozgunov, Pavel and Jaki, Thomas and Paoletti, Xavier (2020) Using a Dose-Finding Benchmark to Quantify the Loss Incurred by Dichotomisation in Phase II Dose-Ranging Studies. Biometrical Journal, 62 (7). pp. 1717-1729. ISSN 0323-3847

Mozgunov, Pavel and Gasparini, Mauro and Jaki, Thomas (2020) A surface-free design for phase I dual-agent combination trials. Statistical Methods in Medical Research, 29 (10). pp. 3093-3109. ISSN 0962-2802

Mozgunov, Pavel and Jaki, Thomas Friedrich and Paoletti, Xavier (2020) A benchmark for dose finding studies with continuous outcomes. Biostatistics, 21 (2). 189–201. ISSN 1465-4644

Mozgunov, Pavel and Jaki, Thomas (2019) A flexible design for advanced Phase I/II clinical trials with continuous efficacy endpoints. Biometrical Journal, 61 (6). pp. 1477-1492. ISSN 0323-3847

Mozgunov, Pavel and Jaki, Thomas Friedrich and Gasparini, Mauro (2019) Loss Functions in Restricted Parameter Spaces and Their Bayesian Applications. Journal of Applied Statistics, 46 (13). pp. 2314-2337. ISSN 0266-4763

Saint-Hilary, Gaelle and Robert, Veronique and Gasparini, Mauro and Jaki, Thomas Friedrich and Mozgunov, Pavel (2019) A novel measure of drug benefit–risk assessment based on Scale Loss Score. Statistical Methods in Medical Research, 28 (9). pp. 2738-2753. ISSN 0962-2802

Mozgunov, Pavel and Jaki, Thomas Friedrich and Paoletti, Xavier (2018) Randomized dose-escalation designs for drug combination cancer trials with immunotherapy. Journal of Biopharmaceutical Statistics, 29 (2). pp. 359-377. ISSN 1054-3406

Mozgunov, Pavel and Jaki, Thomas Friedrich (2018) An information-theoretic Phase I/II design for molecularly targeted agents that does not require an assumption of monotonicity. Journal of the Royal Statistical Society: Series C (Applied Statistics), 68 (2). pp. 347-367. ISSN 0035-9254

Mozgunov, Pavel and Beccuti, Marco and Horvath, Andras and Jaki, Thomas Friedrich and Sirovich, Roberta and Bibbona, Enrico (2018) A review of the deterministic and diffusion approximations for stochastic chemical reaction networks. Reaction Kinetics, Mechanisms and Catalysis, 123 (2). pp. 289-312. ISSN 1878-5190

Kelbert, Mark and Mozgunov, Pavel (2017) Generalization of Cramér-Rao and Bhattacharyya inequalities for the weighted covariance matrix. Mathematical Communications, 22 (1). pp. 25-40. ISSN 1331-0623

Kelbert, Mark and Mozgunov, Pavel (2015) Shannon’s differential entropy asymptotic analysis in a Bayesian problem. Mathematical Communications, 20 (2). pp. 219-228. ISSN 1331-0623

Kelbert, Mark and Mozgunov, Pavel (2015) Asymptotic behaviour of the weighted Renyi, Tsallis and Fisher entropies in a Bayesian problem. Eurasian Mathematical Journal, 6 (2). pp. 6-17. ISSN 2077-9879

Thesis

Daniells, Libby and Mozgunov, Pavel and Jaki, Thomas and Barnett, Helen and Bedding, Alun (2025) Design and Analysis of Basket Clinical Trials. PhD thesis, Lancaster University.

Greenstreet, Peter and Jaki, Thomas and Mozgunov, Pavel (2024) Design and analysis of platform trials. PhD thesis, Lancaster University.

Mozgunov, Pavel and Jaki, Thomas (2018) Adaptive designs for complex dose finding studies. PhD thesis, Lancaster University.