Items where Author is "Hooper, Nigel M."

Journal Article

Parkin, Ed and Watt, Nicole T. and Hussain, Ishrut and Eckman, Elizabeth A. and Eckman, Christopher B. and Manson, Jean C. and Baybutt, Herbert N. and Turner, Anthony J. and Hooper, Nigel M. (2007) Cellular pion protein regulates beta-secretase cleavage of the Alzheimers amyloid precurs protein. Proceedings of the National Academy of Sciences of the United States of America, 104 (26). pp. 11062-11067. ISSN 0027-8424

Leisle, Lilia and Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (2005) Angiotensin-converting enzyme as a GPlase : a critical reevaluation. Nature Medicine, 11 (11). pp. 1139-1140. ISSN 1078-8956

Lambert, Daniel W. and Yarski, Mike and Warner, Fiona J. and Thornhill, Paul and Parkin, Edward T. and Smith, A. Ian and Hooper, Nigel M. and Turner, Anthony J. (2005) Tumor Necrosis Factor- Convertase (ADAM17) Mediates Regulated Ectodomain Shedding of the Severe-acute Respiratory Syndrome-Coronavirus (SARS-CoV) Receptor, Angiotensin-converting Enzyme-2 (ACE2). Journal of Biological Chemistry, 280 (34). pp. 30113-30119. ISSN 1083-351X

Allinson, Tobias M. J. and Parkin, Edward T. and Condon, Thomas P. and Schwager, Sylva L. U. and Sturrock, Edward D. and Turner, Anthony J. and Hooper, Nigel M. (2004) The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein. European Journal of Biochemistry, 271 (12). pp. 2539-2547. ISSN 0014-2956

Parkin, Edward T. and Watt, Nicole T. and Turner, Anthony J. and Hooper, Nigel M. (2004) Dual Mechanisms for Shedding of the Cellular Prion Protein. Journal of Biological Chemistry, 279 (12). pp. 11170-11178. ISSN 1083-351X

Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (2004) Secretase-mediated cell surface shedding of the angiotensin-converting enzyme. Protein and Peptide Letters, 11. pp. 423-432. ISSN 0929-8665

Allinson, Tobias M. J. and Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (2003) ADAMs family members as amyloid precursor protein -secretases. Journal of Neuroscience Research, 74 (3). pp. 342-352. ISSN 0360-4012

Parkin, Edward T. and Tan, Fulong and Skidgel, Randal A. and Turner, Anthony J. and Hooper, Nigel M. (2003) The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts. Journal of Cell Science, 116 (15). pp. 3079-3087. ISSN 0021-9533

Parkin, Edward T. and Trew, Alison and Christie, Gary and Faller, Andrew and Mayer, Ruth and Turner, Anthony J. and Hooper, Nigel M. (2002) Structure-Activity Relationship of Hydroxamate-Based Inhibitors on the Secretases that Cleave the Amyloid Precursor Protein, Angiotensin Converting Enzyme, CD23, and Pro-Tumor Necrosis Factor. Biochemistry, 41 (15). pp. 4972-4981. ISSN 0006-2960

Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (2001) Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase. Biochemical Journal, 358 (1). pp. 209-216. ISSN 0264-6021

Alfalah, Marwan and Parkin, Edward T. and Jacob, Ralf and Sturrock, Edward D. and Mentele, Reinhard and Turner, Anthony J. and Hooper, Nigel M. and Naim, Hassan Y. (2001) A Point Mutation in the Juxtamembrane Stalk of Human Angiotensin I-converting Enzyme Invokes the Action of a Distinct Secretase. Journal of Biological Chemistry, 276 (24). pp. 21105-21109. ISSN 1083-351X

Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (1999) Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein. Biochemical Journal, 344 (1). pp. 23-30. ISSN 0264-6021

Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (1999) Caveolae-like membranes and the amyloid precursor protein : a critical reassessment. Journal of Neurochemistry, 72 (Supple). S71. ISSN 0022-3042

Parkin, Edward T. and Hussain, Ishrut and Karran, Eric H. and Turner, Anthony J. and Hooper, Nigel M. (1999) Characterization of Detergent-Insoluble Complexes Containing the Familial Alzheimer's Disease-Associated Presenilins. Journal of Neurochemistry, 72 (4). pp. 1534-1543. ISSN 0022-3042

Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (1999) Caveolae-like membranes and the amyloid precursor protein : a critical reassessment. British Neuroscience Association Abstracts, 15. p. 59.

Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (1998) Detergent solubility and processing of the familial Alzheimer's disease-related presenilin proteins. Biochemical Society Transactions, 26 (3). S241. ISSN 0300-5127

Contribution in Book/Report/Proceedings

Hooper, Nigel M. and Trew, A. J. and Parkin, Edward T. and Turner, Anthony J. (2000) The role of proteolysis in Alzheimer's disease. In: Cellular peptidases in immune functions and diseases :. Plenum, pp. 379-390.

Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (1999) Distribution of presenilins and amyloid precursor protein in detergent-insoluble membrane domains. In: Alzheimer's disease : methods and protocols :. Humana Press, pp. 345-360.

Contribution to Conference

Parkin, Edward T. and Turner, Anthony J. and Hooper, Nigel M. (2000) The Alzheimer's amyloid precursor protein a-secretase and the angiotensin converting enzyme secretase exhibit closely related enzyme activities. In: 18th International Congress of Biochemistry and Molecular Biology, 1900-01-01.