Items where Author is "Hawkes, Cheryl A."

Journal Article

Holt, Daniel and Contu, Laura and Wood, Alice and Chadwick, Hannah and Alborelli, Ilaria and Insilla, Andrea Cacciato and Crea, Francesco and Hawkes, Cheryl A. (2024) Both Maternal High-Fat and Post-Weaning High-Carbohydrate Diets Increase Rates of Spontaneous Hepatocellular Carcinoma in Aged-Mouse Offspring. Nutrients, 16 (16): 2805. ISSN 2072-6643

Kelly, Louise and Brown, Christopher and Michalik, Daniel and Hawkes, Cheryl A. and Aldea, Roxana and Agarwal, Nivedita and Salib, Rami and Alzetani, Aiman and Ethell, Douglas W and Counts, Scott E. and de Leon, Mony and Fossati, Silvia and Koronyo‐Hamaoui, Maya and Piazza, Fabrizio and Rich, Steven A. and Wolters, Frank J. and Snyder, Heather and Ismail, Ozama and Elahi, Fanny and Proulx, Steven T. and Verma, Ajay and Wunderlich, Hilary and Haack, Mareike and Dodart, Jean Cosme and Mazer, Norman and Carare, Roxana O. (2024) Clearance of interstitial fluid (ISF) and CSF (CLIC) group‐part of Vascular Professional Interest Area (PIA), updates in 2022‐2023. Cerebrovascular disease and the failure of elimination of Amyloid‐β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy. Alzheimer's and Dementia : the journal of the Alzheimer's Association, 20 (2). pp. 1421-1435. ISSN 1552-5260

Contu, Laura and Heath, Christopher J. and Hawkes, Cheryl A. (2022) Appetitive Motivation and Associated Neurobiology Change Differentially across the Life Course of Mouse Offspring Exposed to Peri- and Postnatal High Fat Feeding. Nutrients, 14 (23): 5161. ISSN 2072-6643

Nizari, Shereen and Hawkes, Cheryl A. and Hattori, Yorito and Mishra, Anusha (2022) Editorial: The Neurovascular Unit as a Potential Biomarker and Therapeutic Target in Cerebrovascular Disease. Frontiers in Aging Neuroscience, 14: 908716. ISSN 1663-4365

Carare, Roxana O. and Aldea, Roxana and Agarwal, Nivedita and Bacskai, Brian J. and Bechman, Ingo and Boche, Delphine and Bu, Guojun and Bulters, Diederik and Clemens, Alt and Counts, Scott E. and de Leon, Mony and Eide, Per K. and Fossati, Silvia and Greenberg, Steven M. and Hamel, Edith and Hawkes, Cheryl A. and Koronyo-Hamaoui, Maya and Hainsworth, Atticus H. and Holtzman, David and Ihara, Masafumi and Jefferson, Angela and Kalaria, Raj N. and Kipps, Christopher M. and Kanninen, Katja M. and Leinonen, Ville and McLaurin, Jo Anne and Miners, Scott and Malm, Tarja and Nicoll, James A.R. and Piazza, Fabrizio and Paul, Gesine and Rich, Steven M. and Saito, Satoshi and Shih, Andy and Scholtzova, Henrieta and Snyder, Heather and Snyder, Peter and Thormodsson, Finnbogi Rutur and van Veluw, Susanne J. and Weller, Roy O. and Werring, David J. and Wilcock, Donna and Wilson, Mark R. and Zlokovic, Berislav V. and Verma, Ajay (2020) Clearance of interstitial fluid (ISF) and CSF (CLIC) group—part of Vascular Professional Interest Area (PIA) : Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 12 (1): e12053. ISSN 2352-8729

Alimajstorovic, Zerin and Pascual-Baixauli, Ester and Hawkes, Cheryl A. and Sharrack, Basil and Loughlin, A. Jane and Romero, Ignacio A. and Preston, Jane E. (2020) Cerebrospinal fluid dynamics modulation by diet and cytokines in rats. Fluids and Barriers of the CNS, 17 (1): 10. ISSN 2045-8118

Carare, Roxana Octavia and Teeling, Jessica Liesbeth and Hawkes, Cheryl A. and Püntener, Ursula and Weller, Roy O. and Nicoll, James A.R. and Perry, Victor Hugh (2019) Immune complex formation impairs the elimination of solutes from the brain : Implications for immunotherapy in Alzheimer's disease. Acta Neuropathologica Communications, 2 (1): 48.

Nizari, Shereen and Carare, Roxana O. and Romero, Ignacio A. and Hawkes, Cheryl A. (2019) 3D reconstruction of the neurovascular unit reveals differential loss of cholinergic innervation in the cortex and hippocampus of the adult mouse brain. Frontiers in Aging Neuroscience, 11: 172. ISSN 1663-4365

Albargothy, Nazira J. and Johnston, David A. and MacGregor-Sharp, Matthew and Weller, Roy O. and Verma, Ajay and Hawkes, Cheryl A. and Carare, Roxana O. (2018) Convective influx/glymphatic system : tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways. Acta Neuropathologica, 136 (1). pp. 139-152. ISSN 0001-6322

Horsburgh, Karen and Wardlaw, Joanna M. and van Agtmael, Tom and Allan, Stuart M. and Ashford, Mike L.J. and Bath, Philip M. and Brown, Rosalind and Berwick, Jason and Cader, M. Zameel and Carare, Roxana O. and Davis, John B. and Duncombe, Jessica and Farr, Tracy D. and Fowler, Jill H. and Goense, Jozien and Granata, Alessandra and Hall, Catherine N. and Hainsworth, Atticus H. and Harvey, Adam and Hawkes, Cheryl A. and Joutel, Anne and Kalaria, Rajesh N. and Kehoe, Patrick G. and Lawrence, Catherine B. and Lockhart, Andy and Love, Seth and Macleod, Malcolm R. and Macrae, I. Mhairi and Markus, Hugh S. and McCabe, Chris and McColl, Barry W. and Meakin, Paul J. and Miller, Alyson and Nedergaard, Maiken and O'Sullivan, Michael and Quinn, Terry J. and Rajani, Rikesh and Saksida, Lisa M. and Smith, Colin and Smith, Kenneth J. and Touyz, Rhian M. and Trueman, Rebecca C. and Wang, Tao and Williams, Anna and Williams, Steven C.R. and Work, Lorraine M. (2018) Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. Clinical Science, 132 (8). pp. 851-868. ISSN 0143-5221

Nizari, Shereen and Romero, Ignacio A. and Hawkes, Cheryl A. (2017) The role of perivascular innervation and neurally mediated vasoreactivity in the pathophysiology of Alzheimer's disease. Clinical Science, 131 (12). pp. 1207-1214. ISSN 0143-5221

Contu, Laura and Hawkes, Cheryl A. (2017) A review of the impact of maternal obesity on the cognitive function and mental health of the offspring. International Journal of Molecular Sciences, 18 (5): 1093. ISSN 1661-6596

Morris, Alan W.J. and Sharp, Matthew Mac Gregor and Albargothy, Nazira J. and Fernandes, Rute and Hawkes, Cheryl A. and Verma, Ajay and Weller, Roy O. and Carare, Roxana O. (2016) Vascular basement membranes as pathways for the passage of fluid into and out of the brain. Acta Neuropathologica, 131 (5). pp. 725-736. ISSN 0001-6322

Nizari, Shereen and Carare, Roxana O. and Hawkes, Cheryl A. (2016) Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet. Scientific Reports, 6: 21981. ISSN 2045-2322

Weller, Roy O. and Hawkes, Cheryl A. and Carare, Roxana O. and Hardy, John (2015) Does the difference between PART and Alzheimer’s disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau? Acta Neuropathologica, 129 (5). pp. 763-766. ISSN 0001-6322

Hawkes, Cheryl A. and Gentleman, Steve M. and Nicoll, James A. and Carare, Roxana O. (2015) Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring. Journal of Pathology, 235 (4). pp. 619-631. ISSN 0022-3417

Weller, Roy O. and Hawkes, Cheryl A. and Kalaria, Raj N. and Werring, David J. and Carare, Roxana O. (2015) White matter changes in dementia : Role of impaired drainage of interstitial fluid. Brain Pathology, 25 (1). pp. 63-78. ISSN 1015-6305

Morris, Alan W.J. and Carare, Roxana O. and Schreiber, Stefanie and Hawkes, Cheryl A. (2014) The cerebrovascular basement membrane : Role in the clearance of β-amyloid and cerebral amyloid angiopathy. Frontiers in Aging Neuroscience, 6 (SEP): 251. ISSN 1663-4365

Maki, Takakuni and Okamoto, Yoko and Carare, Roxana O. and Hase, Yoshiki and Hattori, Yorito and Hawkes, Cheryl A. and Saito, Satoshi and Yamamoto, Yumi and Terasaki, Yasukazu and Ishibashi-Ueda, Hatsue and Taguchi, Akihiko and Takahashi, Ryosuke and Miyakawa, Taihei and Kalaria, Raj N. and Lo, Eng H. and Arai, Ken and Ihara, Masafumi (2014) Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid. Annals of Clinical and Translational Neurology, 1 (8). pp. 519-533. ISSN 2328-9503

Hawkes, Cheryl A. and Jayakody, Nimeshi and Johnston, David A. and Bechmann, Ingo and Carare, Roxana O. (2014) Failure of perivascular drainage of β-amyloid in cerebral amyloid angiopathy. Brain Pathology, 24 (4). pp. 396-403. ISSN 1015-6305

Hawkes, Cheryl A. and Carare, Roxana O. and Weller, Roy O. (2014) Amyloid and tau in the brain in sporadic Alzheimer's disease : Defining the chicken and the egg. Acta Neuropathologica, 127 (4). pp. 617-618. ISSN 0001-6322

Hawkes, Cheryl A. and Shaw, James E. and Brown, Mary and Sampson, Anthony P. and McLaurin, Joanne and Carare, Roxana O. (2013) MK886 reduces cerebral amyloid angiopathy severity in TgCRND8 mice. Neurodegenerative Diseases, 13 (1). pp. 17-23. ISSN 1660-2854

Hawkes, Cheryl A. and Michalski, Dominik and Anders, Rebecca and Nissel, Sabine and Grosche, Jens and Bechmann, Ingo and Carare, Roxana O. and Härtig, Wolfgang (2013) Stroke-induced opposite and age-dependent changes of vessel-associated markers in co-morbid transgenic mice with Alzheimer-like alterations. Experimental Neurology, 250. pp. 270-281. ISSN 0014-4886

Hawkes, Cheryl A. and Gatherer, Maureen and Sharp, Matthew M. and Dorr, Adrienne and Yuen, Ho Ming and Kalaria, Rajesh and Weller, Roy O. and Carare, Roxana O. (2013) Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain. Aging Cell, 12 (2). pp. 224-236. ISSN 1474-9718

Hawkes, Cheryl A. and Deng, LeHua H. and Fenili, Daniela and Nitz, Mark and McLaurin, JoAnne A. (2012) In vivo uptake of β-amyloid by non-plaque associated microglia. Current Alzheimer Research, 9 (8). pp. 890-901. ISSN 1567-2050

Dorr, Adrienne and Sahota, Bhupinder and Chinta, Lakshminarayan V. and Brown, Mary E. and Lai, Aaron Y. and Ma, Keran and Hawkes, Cheryl A. and McLaurin, Joanne and Stefanovic, Bojana (2012) Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer's disease. Brain, 135 (10). pp. 3039-3050. ISSN 0006-8950

Hawkes, Cheryl A. and Sullivan, Patrick M. and Hands, Sarah and Weller, Roy O. and Nicoll, James A.R. and Carare, Roxana O. (2012) Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele. PLoS ONE, 7 (7): e41636. ISSN 1932-6203

Finney, Constance A.M. and Hawkes, Cheryl A. and Kain, Dylan C. and Dhabangi, Aggrey and Musoke, Charles and Cserti-Gazdewich, Christine and Oravecz, Tamas and Conrad Liles, W. and Kain, Kevin C. (2011) S1P is associated with protection in human and experimental cerebral malaria. Molecular Medicine, 17 (7-8). pp. 717-725. ISSN 1076-1551

Hawkes, Cheryl A. and Härtig, Wolfgang and Kacza, Johannes and Schliebs, Reinhard and Weller, Roy O. and Nicoll, James A. and Carare, Roxana O. (2011) Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy. Acta Neuropathologica, 121 (4). pp. 431-443. ISSN 0001-6322

Hawkes, Cheryl A. and Deng, Le Hua and Shaw, James E. and Nitz, Mark and McLaurin, Joanne (2010) Small molecule β-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease. European Journal of Neuroscience, 31 (2). pp. 203-213. ISSN 0953-816X

Hawkes, Cheryl A. and Ng, Vivian and McLaurin, Joanne (2009) Small molecule inhibitors of Aβ-aggregation and neurotoxicity. Drug Development Research, 70 (2). pp. 111-124. ISSN 0272-4391

Hawkes, Cheryl A. and McLaurin, Joanne (2009) Selective targeting of perivascular macrophages for clearance of β-amyloid in cerebral amyloid angiopathy. Proceedings of the National Academy of Sciences of the United States of America, 106 (4). pp. 1261-1266. ISSN 0027-8424

Hawkes, Cheryl A. and McLaurin, Jo Anne (2008) Clinical immunotherapy trials in Alzheimer's disease. Drug Discovery Today: Therapeutic Strategies, 5 (3). pp. 177-183. ISSN 1740-6773

Sun, Yedi and Zhang, Guohua and Hawkes, Cheryl A. and Shaw, James E. and McLaurin, Jo Anne and Nitz, Mark (2008) Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation. Bioorganic and Medicinal Chemistry, 16 (15). pp. 7177-7184. ISSN 0968-0896

Lovegrove, Fiona E. and Gharib, Sina A. and Patel, Samir N. and Hawkes, Cheryl A. and Kain, Kevin C. and Liles, W. Conrad (2007) Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria. American Journal of Pathology, 171 (6). pp. 1894-1903. ISSN 0002-9440

Hawkes, Cheryl A. and McLaurin, Joanne (2007) Immunotherapy as treatment for Alzheimer's disease. Expert Review of Neurotherapeutics, 7 (11). pp. 1535-1548. ISSN 1473-7175

McLaurin, Jo Anne and Kierstead, Meredith E. and Brown, Mary E. and Hawkes, Cheryl A. and Lambermon, Mark H.L. and Phinney, Amie L. and Darabie, Audrey A. and Cousins, Julian E. and French, Janet E. and Lan, Melissa F. and Chen, Fusheng and Wong, Sydney S.N. and Mount, Howard T.J. and Fraser, Paul E. and Westaway, David and George-Hyslop, Peter St (2006) Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model. Nature Medicine, 12 (7). pp. 801-808. ISSN 1078-8956

Contribution in Book/Report/Proceedings

Weller, Roy O. and Carare, Roxana O. and Hawkes, Cheryl A. and Galea, Ian (2015) Pathophysiology of lymphatic drainage of the central nervous system : Implications for the pathophysiology of multiple sclerosis. In: Multiple Sclerosis : A Mechanistic View. Elsevier Inc., pp. 479-501. ISBN 9780128007631