Items where Author is "Goralski, Kerry B"

Journal Article

McKeown, Brendan T and Relja, Nicholas J and Hall, Steven R and Gebremeskel, Simon and MacLeod, Jeanna M and Veinotte, Chansey J and Bennett, Leah G and Ohlund, Leanne B and Sleno, Lekha and Jakeman, David L and Berman, Jason N and Johnston, Brent and Goralski, Kerry B (2022) Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models. Canadian journal of physiology and pharmacology, 100 (11). pp. 1065-1076. ISSN 0008-4212

Dahn, Margaret L. and Cruickshank, Brianne M. and Jackson, Ainsleigh J. and Dean, Cheryl and Holloway, Ryan W. and Hall, Steve and Coyle, Krysta M. and Maillet, Hillary and Waisman, David M. and Goralski, Kerry B and Giacomantonio, Carman A. and Weaver, Ian C. G. and Marcato, Paola (2020) Decitabine Response in Breast Cancer Requires Efficient Drug Processing and Is Not Limited by Multidrug Resistance. Molecular Cancer Therapeutics, 19 (5). 1110–1122.

Tomko, Andrea and O'Leary, Lauren and Trask, Hilary and Achenbach, John C and Hall, Steven R and Goralski, Kerry B and Ellis, Lee D and Dupré, Denis J (2019) Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer. Frontiers in Pharmacology, 10. p. 1124. ISSN 1663-9812

Forget, Stephanie M and Robertson, Andrew W and Hall, Steven R and MacLeod, Jeanna M and Overy, David P and Kerr, Russell G and Goralski, Kerry B and Jakeman, David L (2018) Isolation of a jadomycin incorporating L-ornithine, analysis of antimicrobial activity and jadomycin reactive oxygen species (ROS) generation in MDA-MB-231 breast cancer cells. The Journal of antibiotics, 71 (8). pp. 722-730. ISSN 0021-8820

Hall, Steven Robert and Goralski, Kerry B (2018) ZATT, TDP2, and SUMO2: Breaking the tie that binds TOP2 to DNA. Translational Cancer Research, 7 (4). pp. 1412-16.

Robertson, Andrew W and MacLeod, Jeanna M and MacIntyre, Logan W and Forget, Stephanie M and Hall, Steven R and Bennett, Leah G and Correa, Hebelin and Kerr, Russell G and Goralski, Kerry B and Jakeman, David L (2018) Post Polyketide Synthase Carbon-Carbon Bond Formation in Type-II PKS-Derived Natural Products from Streptomyces venezuelae. Journal of Organic Chemistry, 83 (4). pp. 1876-1890. ISSN 0022-3263

Hall, Steven R and Toulany, Jay and Bennett, Leah G and Martinez-Farina, Camilo F and Robertson, Andrew W and Jakeman, David L and Goralski, Kerry B (2017) Jadomycins Inhibit Type II Topoisomerases and Promote DNA Damage and Apoptosis in Multidrug-Resistant Triple-Negative Breast Cancer Cells. Journal of Pharmacology and Experimental Therapeutics, 363 (2). pp. 196-210. ISSN 0022-3565

Hall, Steven R and Blundon, Heather L and Ladda, Matthew A and Robertson, Andrew W and Martinez-Farina, Camilo F and Jakeman, David L and Goralski, Kerry B (2015) Jadomycin breast cancer cytotoxicity is mediated by a copper-dependent, reactive oxygen species-inducing mechanism. Pharmacology research & perspectives, 3 (2). e00110. ISSN 2052-1707

Issa, Mark E and Hall, Steven R and Dupuis, Stephanie N and Graham, Cathy L and Jakeman, David L and Goralski, Kerry B (2014) Jadomycins are cytotoxic to ABCB1-, ABCC1-, and ABCG2-overexpressing MCF7 breast cancer cells. Anti-Cancer Drugs, 25 (3). pp. 255-69. ISSN 0959-4973

Thesis

Hall, Steve and Goralski, Kerry B (2018) The Anticancer Activity and Mechanisms of Action of Jadomycins in Multidrug Resistant Human Breast Cancer Cells. PhD thesis, Dalhousie University.