Items where Author is "El-Agnaf, Omar M. A."

Singh, Maneesh N. and Stringfellow, Helen F. and Taylor, Siân E. and Ashton, Kate M. and Ahmad, Mushfika and Abdo, Khalil R. and El-Agnaf, Omar M. A. and Martin-Hirsch, Pierre L. and Martin, Frank L. (2008) Elevated expression of CYP1A1 and y-SYNUCLEIN in human ectopic (ovarian) endometriosis compared with eutopic endometrium. Molecular Human Reproduction, 14 (11). pp. 655-663. ISSN 1460-2407

Masad, Atef and Hayes, Lee and Tabner, Brian and Turnbull, Stuart and Cooper, Leanne and Fullwood, Nigel J. and German, Matthew and Kametani, Fuyuki and El-Agnaf, Omar M. A. and Allsop, David (2007) Copper-mediated formation of hydrogen peroxide from the amylin peptide : a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus? FEBS Letters, 581 (18). pp. 3489-3493. ISSN 0014-5793

Tabner, Brian J. and Turnbull, Stuart and King, Jennifer and Benson, Fiona E. and El-Agnaf, Omar M. A. and Allsop, David (2006) A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on β-amyloid and α-synuclein. Free Radical Research, 40 (7). pp. 731-739. ISSN 1071-5762

El-Agnaf, Omar M. A. and Salem, Sultan A. and Paleologou, Katerina E. and Curran, Martin D. and Gibson, Mark J. and Court, Jennifer A. and Schlossmacher, Michael G. and Allsop, David (2006) Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease. FASEB Journal, 20 (3). pp. 419-425. ISSN 1530-6860

Tabner, Brian J. and El-Agnaf, Omar M. A. and German, M. J. and Fullwood, Nigel J. and Allsop, David (2005) Protein aggregation, metals and oxidative stress in neurodegenerative diseases. Biochemical Society Transactions, 33 (5). pp. 1082-1086. ISSN 0300-5127

Tabner, Brian J. and El-Agnaf, Omar M. A. and Turnbull, Stuart and German, Matthew J. and Paleologou, Katerina E. and Hayashi, Yoshihito and Cooper, Leanne J. and Fullwood, Nigel and Allsop, David (2005) Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia. Journal of Biological Chemistry, 280 (43). pp. 35789-35792. ISSN 1083-351X

El-Agnaf, Omar M. A. and Paleologou, Katerina E. and Greer, Brett and Abogrein, Abdulmawala M. and King, Jennifer and Salem, Sultan A. and Fullwood, Nigel J. and Benson, Fiona E. and Hewitt, Rebecca and Ford, Kirstie J. and Martin, Frank and Harriott, Patrick and Cookson, Mark R. and Allsop, David (2004) A strategy for designing inhibitors of α-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders. FASEB Journal, 18 (11). pp. 1315-1317. ISSN 0892-6638

Moore, S. A. and Huckerby, T. N. and Gibson, G. L. and Fullwood, Nigel J. and Turnbull, Iain and Tabner, Brian J. and El-Agnaf, Omar M. A. and Allsop, David (2004) Both the D-(+) and L-(-) enantiomers of nicotine inhibit Aβ aggregation and cytotoxicity. Biochemistry, 43 (3). pp. 819-826. ISSN 0006-2960

Martin, Frank and Allsop, David and Williamson, Sally J. M. and Paleologou, Katerina E. and El-Agnaf, Omar M. A. (2004) α-Synuclein and the pathogenesis of Parkinson’s disease. Protein and Peptide Letters, 11 (3). pp. 229-237. ISSN 0929-8665

Martin, Frank and Williamson, Sally J. M. and Paleologou, Katerina E. and Hewitt, R. and El-Agnaf, Omar M. A. and Allsop, David (2003) Fe(II)-induced DNA damage in α-synuclein-transfected human dopaminergic BE(2)-M17 neuroblastoma cells: detection by the Comet assay. Journal of Neurochemistry, 87 (3). pp. 620-630. ISSN 0022-3042

El-Agnaf, Omar M. A. and Salem, Sultan A. and Paleologou, Katerina E. and Cooper, Leanne J. and Fullwood, Nigel J. and Gibson, Mark J. and Curran, Martin D. and Court, Jennifer A. and Mann, David M. A. and Ikeda, Shu-Ichi and Cookson, Mark R. and Hardy, John and Allsop, David (2003) α-Synuclein implicated in Parkinson’s disease is present in extracellular biological fluids, including human plasma. FASEB Journal, 17 (13). pp. 1945-1947. ISSN 0892-6638

El-Agnaf, Omar M. A. and Walsh, Dominic M. and Allsop, David (2003) Soluble oligomers for the diagnosis of neurodegenerative diseases. Lancet Neurology, 2 (8). pp. 461-462. ISSN 1474-4422

Tabner, Brian J. and Turnbull, Stuart and El-Agnaf, Omar M. A. and Allsop, David (2003) Direct production of reactive oxygen species from aggregating proteins and peptides implicated in the pathogenesis of neurodegenerative diseases. Current Medicinal Chemistry Immunology Endocrine and Metabolic Agents, 3 (4). pp. 299-308. ISSN 1568-0134

Tabner, Brian J. and Turnbull, Stuart and El-Agnaf, Omar M. A. and Allsop, David (2002) Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease. Free Radical Biology and Medicine, 32 (11). pp. 1076-1083. ISSN 0891-5849

Allsop, David and Swanson, Linda and Moore, Susan and Davies, Yvonne and York, Amber and El-Agnaf, Omar M. A. and Soutar, Ian (2001) Fluorescence anisotropy : a method for early detection of Alzheimer β-peptide (Aβ) aggregation. Biochemical and Biophysical Research Communications, 285 (1). pp. 58-63. ISSN 1090-2104

Turnbull, Stuart and Tabner, Brian J. and El-Agnaf, Omar M. A. and Twyman, Lance J. and Allsop, David (2001) New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps. Free Radical Biology and Medicine, 30 (10). pp. 1154-1162. ISSN 0891-5849

Turnbull, Stuart and Tabner, Brian J. and Moore, Susan and Davies, Yvonne and El-Agnaf, Omar M. A. and Allsop, David (2001) α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro. Free Radical Biology and Medicine, 30 (10). pp. 1163-1170. ISSN 0891-5849

Tabner, Brian J. and Turnbull, Stuart and El-Agnaf, Omar M. A. and Allsop, David (2001) Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. Current Topics in Medicinal Chemistry, 1. pp. 483-493. ISSN 1568-0266