Items where Author is "Broughton, Susan"

Holland, Carol and Dravecz, Nikolette and Broughton, Susan and Davis, Sally Fowler and Dixon, Mandy (2024) INTERVENTIONS FOR COGNITIVE FRAILTY: DELPHI CONSENSUS WITH RESEARCHERS, CLINICIANS, AND EXPERTS BY EXPERIENCE. Innovation in Aging, 8 (Supple). p. 364. ISSN 2399-5300

Holland, Carol and Dravecz, Nikolett and Owens, Lauren and Benedetto, Alexandre and Dias, Irundika and Gow, Alan and Broughton, Susan (2024) Understanding exogenous factors and biological mechanisms for cognitive frailty : A multidisciplinary scoping review. Ageing Research Reviews, 101: 102461. ISSN 1568-1637

Malik, Yasir and Kulaberoglu, Yavuz and Anver, Shajahan and Javidnia, Sara and Borland, Gillian and Rivera, Rene and Cranwell, Stephen and Medelbekova, Danel and Svermova, Tatiana and Thomson, Jackie and Broughton, Susan and von der Haar, Tobias and Selman, Colin and Tullet, Jennifer M. A. and Alic, Nazif (2024) Disruption of tRNA biogenesis enhances proteostatic resilience, improves later-life health, and promotes longevity. Plos Biology, 22 (10): e3002853. ISSN 1544-9173

Ng, Tze Chang (Justin) and Broughton, Susan and Benedetto, Alexandre (2023) Introducing Commensal Bacteria from Caenorhabditis elegans to Drosophila melanogaster : Effects on Health, Ageing and Insulin-like Signalling. Masters thesis, Lancaster University.

Clancy, David and Chtarbanova, Stanislava and Broughton, Susan (2023) Editorial: Model organisms in aging research: Drosophila melanogaster. Frontiers in Aging, 3: 1118299. ISSN 2673-6217

Griffiths, Tia and Broughton, Susan (2023) Elucidating the role of Insulin/IGF-like signalling in the response of lifespan to dietary restriction in Drosophila melanogaster. Masters thesis, Lancaster University.

Dravecz, Nikolett and Shaw, Tommy and Davies, Isabella and Brown, Casey and Ormerod, Lewis and Vu, Gin and Walker, Tyler and Taank, Taran and Shirras, Alan and Broughton, Susan (2022) Reduced Insulin Signalling Targeted to Serotonergic Neurons but Not Other Neuronal Subtypes Extends Lifespan in Drosophila melanogaster. Frontiers in Aging Neuroscience, 14: 893444. ISSN 1663-4365

Hughes, Rebecca and Whittingham-Dowd, Jayde and Clapcote, Stephen and Broughton, Susan and Dawson, Neil (2022) Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behaviour in a mouse model of autism-associated 2p16.3 deletion. Autism Research, 15 (4). pp. 614-627. ISSN 1939-3792

Shaw, Tommy and Broughton, Susan (2021) The Effects of Reduced Insulin/IGF-like Signalling in the CNS on Lifespan, Brain Ageing and Stress Resistance in Drosophila melanogaster. Masters thesis, Lancaster University.

Dravecz, Nikolett and Broughton, Susan and Shirras, Alan (2020) Insulin/IGF-like signalling and brain ageing in Drosophila melanogaster. PhD thesis, Lancaster University.

Hughes, Rebecca and Whittingham-Dowd, Jayde and Simmons, Rachel and Clapcote, Stephen and Broughton, Susan and Dawson, Neil (2020) Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion. Cerebral Cortex (4). 2358–2371. ISSN 1047-3211

Martinez Corrales, Guillermo and Filer, Danny and Wenz, Katharina C. and Rogan, Abbie and Phillips, George and Li, Mengjia and Feseha, Yodit and Broughton, Susan and Alic, Nazif (2020) Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity. Cell Reports, 30 (6). pp. 1661-1669. ISSN 2211-1247

Hughes, Rebecca and Dawson, Neil and Broughton, Susan (2019) Characterisation of neurodevelopmental disorder and ageing phenotypes in transgenic mouse and fruit fly models of Neurexin1 dysfunction. PhD thesis, Lancaster University.

Wang, Yifan and Broughton, Susan (2019) Insulin/IGF-like signalling and brain ageing in Drosophila melanogaster. Masters thesis, Lancaster University.

Glover, Zoe and Broughton, Susan and Shirras, Alan (2017) Acer, a homologue of the human angiotensin-1 converting enzyme, modulates the response of sleep, glycogen storage, lifespan, fecundity and stress resistance to diet in Drosophila melanogaster. PhD thesis, Lancaster University.

Smith, Emily and Rigby, Rachael and Broughton, Susan (2016) The conservation of suppressor of Cytokine Signalling 3 in mediating intestinal homeostasis. PhD thesis, Lancaster University.

Hodges, Matt and Haji Ismail, Mohd Zamri Bin and Boylan, Michael and Achall, Rajesh and Shirras, Alan and Broughton, Susan (2015) The Drosophila insulin receptor independently modulates lifespan and locomotor senescence. PLoS ONE, 10 (5): 0125312. ISSN 1932-6203

Alic, Nazif and Tullet, Jennifer M. and Niccoli, Teresa and Broughton, Susan and Hoddinott, Matthew P. and Slack, Cathy and Gems, David and Partridge, Linda (2014) Cell-nonautonomous effects of dFOXO/DAF-16 in aging. Cell Reports, 6 (4). pp. 608-616. ISSN 2211-1247

Delury, Craig and Tinker, Claire and Rivers, Samantha and Hodges, Matt and Broughton, Susan and Parkin, Edward (2013) Differential regulation of E-cadherin expression by the soluble ectodomain and intracellular domain of jagged1. International Journal of Biochemistry Research and Review, 3 (4). pp. 278-290. ISSN 2231-086X

Grönke, Sebastian and Clarke, David-Francis and Broughton, Susan and Andrews, T Daniel and Partridge, Linda (2010) Molecular evolution and functional characterization of Drosophila insulin-like peptides. PLoS Genetics, 6 (2): e1000857. ISSN 1553-7404

Ikeya, Tomoatsu and Broughton, Susan and Alic, Nazif and Grandison, Richard and Partridge, Linda (2009) The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila. Proceedings of the Royal Society B: Biological Sciences, 276 (1674). pp. 3799-3807. ISSN 0962-8452

Broughton, Susan and Partridge, Linda (2009) Insulin/IGF-like signalling, the central nervous system and aging. Biochemical Journal, 418 (1). pp. 1-12. ISSN 0264-6021

Broughton, Susan and Alic, Nazif and Slack, Cathy and Bass, Timothy and Ikeya, Tomoatsu and Vinti, Giovanna and Tommasi, Anna Maria and Driege, Yasmine and Hafen, Ernst and Partridge, Linda (2008) Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. PLoS ONE, 3 (11): e3721. ISSN 1932-6203