Items where Author is "Bowie, Andrew G."

Almine, Jessica F. and O'Hare, Craig A. J. and Dunphy, Gillian and Haga, Ismar R. and Naik, Rangeetha J. and Atrih, Abdelmadjid and Connolly, Dympna J. and Taylor, Jordan and Kelsall, Ian R. and Bowie, Andrew G. and Beard, Philippa M. and Unterholzner, Leonie (2017) IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes. Nature Communications, 8: 14392. ISSN 2041-1723

Horan, Kristy A. and Hansen, Kathrine and Jakobsen, Martin R. and Holm, Christian K. and Søby, Stine and Unterholzner, Leonie and Thompson, Mikayla and West, John A. and Iversen, Marie B. and Rasmussen, Simon B. and Ellermann-Eriksen, Svend and Kurt-Jones, Evelyn and Landolfo, Santo and Damania, Blossom and Melchjorsen, Jesper and Bowie, Andrew G. and Fitzgerald, Katherine A. and Paludan, Søren R. (2013) Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors. Journal of Immunology, 190 (5). pp. 2311-2319. ISSN 0022-1767

Mansur, Daniel S. and Maluquer de Motes, Carlos and Unterholzner, Leonie and Sumner, Rebecca P. and Ferguson, Brian J. and Ren, Hongwei and Strnadova, Pavla and Bowie, Andrew G. and Smith, Geoffrey L. (2013) Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry : a mechanism to inhibit NF-κB activation and promote immune evasion and virulence. PLoS Pathogens, 9 (2): e1003183. ISSN 1553-7366

Jin, Tengchuan and Perry, Andrew and Jiang, Jiansheng and Smith, Patrick and Curry, James A. and Unterholzner, Leonie and Jiang, Zhaozhao and Horvath, Gabor and Rathinam, Vijay A. and Johnstone, Ricky W. and Hornung, Veit and Latz, Eicke and Bowie, Andrew G. and Fitzgerald, Katherine A. and Xiao, T. Sam (2012) Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. Immunity, 36 (4). pp. 561-571. ISSN 1074-7613

Unterholzner, Leonie and Sumner, Rebecca P. and Baran, Marcin and Ren, Hongwei and Mansur, Daniel S. and Bourke, Nollaig M. and Randow, Felix and Smith, Geoffrey L. and Bowie, Andrew G. (2011) Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7. PLoS Pathogens, 7 (9): e1002247. ISSN 1553-7366

Unterholzner, Leonie and Bowie, Andrew G. (2011) Innate DNA sensing moves to the nucleus. Cell Host and Microbe, 9 (5). pp. 351-353. ISSN 1931-3128

Unterholzner, Leonie and Keating, Sinead E. and Baran, Marcin and Horan, Kristy A. and Jensen, Søren B. and Sharma, Shruti and Sirois, Cherilyn M. and Jin, Tengchuan and Latz, Eicke and Xiao, T. Sam and Fitzgerald, Katherine A. and Paludan, Søren R. and Bowie, Andrew G. (2010) IFI16 is an innate immune sensor for intracellular DNA. Nature Immunology, 11 (11). pp. 997-1004. ISSN 1529-2908

Bowie, Andrew G. and Unterholzner, Leonie (2008) Viral evasion and subversion of pattern-recognition receptor signalling. Nature Immunology, 8 (12). pp. 911-922. ISSN 1529-2908

Unterholzner, Leonie and Bowie, Andrew G. (2008) The interplay between viruses and innate immune signaling : recent insights and therapeutic opportunities. Biochemical Pharmacology, 75 (3). pp. 589-602. ISSN 0006-2952