Diagnose Pathogens in Drinking Water via Magnetic Surface-Enhanced Raman Scattering (SERS) Assay

Li, Hanbing and Li, Cui and Martin, Francis L. and Zhang, Dayi (2017) Diagnose Pathogens in Drinking Water via Magnetic Surface-Enhanced Raman Scattering (SERS) Assay. Materials Today: Proceedings, 4 (1). pp. 25-31. ISSN 2214-7853

[thumbnail of MATPR_Functional Materials_SERS Pathogen_Zhang]
PDF (MATPR_Functional Materials_SERS Pathogen_Zhang)
MATPR_Functional_Materials_SERS_Pathogen_Zhang.pdf - Accepted Version
Available under License Creative Commons Attribution-NonCommercial-NoDerivs.

Download (516kB)


Abstract Rapid identification and diagnosis of bacteria and other microorganisms is a great challenge for drinking water safety due to the increasing frequency of pathogenic infections. Raman spectroscopy is a non-destructive tool to characterize the biochemical fingerprints of bacterial cells and its signal can be improved by surface-enhanced Raman scattering (SERS). Thus, Raman scattering has a huge potential in fast diagnosis of pathogens in drinking water, with low cost and high reproducibility. In this work, we developed a novel fast diagnosis method to detect aquatic pathogens via magnetic SERS assay. With chemical co-precipitation synthesis and surface glucose reduction, the silver-coated magnetic nanoparticles (Ag@MNPs) had a well-developed core-shell structure and high efficiency to capture bacterial cells. Ag@MNPs achieved 103 enhancement factor for rhodamine 6G and the limit of detection was 10-9 M. The magnetic SERS assay also successfully detected various bacteria (A. baylyi and E. coli) with high sensitivity (105 CFU/mL). This platform provided a promising and easy-operation approach for pathogen detection for food and drinking water safety.

Item Type:
Journal Article
Journal or Publication Title:
Materials Today: Proceedings
Additional Information:
This is the author’s version of a work that was accepted for publication in Materials Today Proceedings. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Materials Today Proceedings, 4, 1, 2017 DOI: 10.1016/j.matpr.2017.01.189
?? magnetic nanoparticles (mnps)silver-coated mnps (ag@mnps)raman spectroscopysurface-enhanced raman scattering (sers) ??
ID Code:
Deposited By:
Deposited On:
21 Mar 2017 11:40
Last Modified:
18 Dec 2023 01:45