Inflammatory demyelinating polyradiculoneuropathy associated with membranous glomerulonephritis and thrombocytopaenia

Emsley, Hedley C. A. and Molloy, Jane (2002) Inflammatory demyelinating polyradiculoneuropathy associated with membranous glomerulonephritis and thrombocytopaenia. Clinical Neurology and Neurosurgery, 105 (1). pp. 23-26. ISSN 0303-8467

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Abstract

A 66-year-old man with secondary progressive multiple sclerosis presented with a flaccid areflexic tetraparesis evolving over a 6-week period. Clinical examination and subsequent investigation confirmed a diagnosis of sub-acute inflammatory demyelinating polyradiculoneuropathy (sub-acute IDP). Nephrotic-range proteinuria and thrombocytopaenia were also noted at the time of presentation - histopathological investigation of the former showed membranous glomerulonephritis as the basis for the protein loss. The IDP, glomerulonephritis and thrombocytopaenia recovered over the same time course. There have been previous reports of either glomerulonephritis or thrombocytopaenia occurring in association with IDP - there are no such reports of all three conditions occurring and resolving simultaneously.

Item Type:
Journal Article
Journal or Publication Title:
Clinical Neurology and Neurosurgery
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2800/2808
Subjects:
ID Code:
84797
Deposited By:
Deposited On:
21 Feb 2017 09:48
Refereed?:
Yes
Published?:
Published
Last Modified:
12 Aug 2020 05:57