X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator

Kneip, S. and McGuffey, C. and Dollar, F. and Bloom, M. S. and Chvykov, V. and Kalintchenko, G. and Krushelnick, K. and Maksimchuk, A. and Mangles, S. P. D. and Matsuoka, T. and Najmudin, Z. and Palmer, C. A. J. and Schreiber, J. and Schumaker, W. and Thomas, A. G. R. and Yanovsky, V. (2011) X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator. Applied Physics Letters, 99 (9). ISSN 0003-6951

Full text not available from this repository.

Abstract

We show that x-rays from a recently demonstrated table top source of bright, ultrafast, coherent synchrotron radiation [Kneip et al., Nat. Phys. 6, 980 (2010)] can be applied to phase contrast imaging of biological specimens. Our scheme is based on focusing a high power short pulse laser in a tenuous gas jet, setting up a plasma wakefield accelerator that accelerates and wiggles electrons analogously to a conventional synchrotron, but on the centimeter rather than tens of meter scale. We use the scheme to record absorption and phase contrast images of a tetra fish, damselfly and yellow jacket, in particular highlighting the contrast enhancement achievable with the simple propagation technique of phase contrast imaging. Coherence and ultrafast pulse duration will allow for the study of various aspects of biomechanics. (C) 2011 American Institute of Physics. [doi:10.1063/1.3627216]

Item Type:
Journal Article
Journal or Publication Title:
Applied Physics Letters
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/3100/3101
Subjects:
ID Code:
84286
Deposited By:
Deposited On:
25 Jan 2017 09:22
Refereed?:
Yes
Published?:
Published
Last Modified:
23 Sep 2020 02:50