Kyrgiou, Maria and Athanasiou, Antonios and Paraskevaidi, Maria and Mitra, Anita and Kalliala, Ilkka and Martin-Hirsch, Pierre Leonard and Arbyn, Marc and Bennett, Phillip and Paraskevaidis, Evangelos (2016) Adverse obstetric outcomes after local treatment for cervical preinvasive and early invasive disease according to cone depth : systematic review and meta-analysis. Obstetrical and Gynecological Survey, 71 (11). pp. 646-648. ISSN 0029-7828
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Abstract
Local cervical treatment for preinvasive cervical disease such as cervical intraepithelial neoplasia (CIN) has been associated with an increased risk of preterm birth, perinatal morbidity, and mortality in a later pregnancy. This meta-analysis aimed to investigate the impact of treatment for cervical preinvasive and early invasive disease on obstetric outcomes and to see how this risk could be modified by the cone depth and comparison group.