Henderson, Robin; and Shimakura, Silvia (2003) A serially correlated gamma frailty model for longitudinal count data. Biometrika, 90 (2). pp. 355-366. ISSN 1464-3510
Full text not available from this repository.Abstract
A Poisson-gamma model is introduced to account for between-subjects heterogeneity and within-subjects serial correlation occurring in longitudinal count data. The model extends the usual time-constant shared frailty approach to allow time-varying serially correlated gamma frailty whilst retaining standard marginal assumptions. A composite likelihood approach to estimation and testing for serial correlation is proposed. The work is motivated by a clinical trial on patient-controlled analgesia where the number of analgesic doses taken by hospital patients in successive time intervals following abdominal surgery is recorded.