The cortical hyperexcitability index (CHi):a new measure for quantifying correlates of visually driven cortical hyperexcitability

Braithwaite, Jason J and Marchant, Rachel and Takahashi, Chie and Dewe, Hayley and Watson, Derrick (2015) The cortical hyperexcitability index (CHi):a new measure for quantifying correlates of visually driven cortical hyperexcitability. Cognitive Neuropsychiatry, 20 (4). pp. 330-348. ISSN 1354-6805

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Abstract

Introduction. Aberrations of visual experience, including visual hallucinations and visual distortions, are known to be associated with increased cortical hyperexcitability. As a consequence, the presence, intensity and frequency of certain experiences may well be indicative of an underlying increase in cortical hyperexcitability. Methods. The current study presents a new proxy measure of cortical hyperexcitability, the Cortical Hyperexcitability Index (CHi). Two hundred and fifty healthy participants completed the CHi with the results subjected to exploratory factor analysis (EFA). Results. The EFA revealed a three-factor model as the most parsimonious solution. The three factors were defined as: (1) heightened visual sensitivity and discomfort; (2) negative aura-type visual aberrations; and (3) positive aura-type visual aberrations. The identification of three factors suggests that multiple mechanisms underlie the notion of cortical hyperexcitability, providing researchers with new and greater precision in delineating these underlying features. Conclusions. The factorial structure of the CHi and the increased precision could aid the interpretation of findings from neuroscientific (i.e., brain imaging/stimulation) examinations of cortical processes underlying aberrant perceptions across a host of clinical, neurological and pathological conditions. As a consequence, the CHi is a useful and comprehensive proxy measure of cortical hyperexcitability with considerable scientific and clinical utility.

Item Type: Journal Article
Journal or Publication Title: Cognitive Neuropsychiatry
Uncontrolled Keywords: /dk/atira/pure/subjectarea/asjc/2700/2738
Subjects:
Departments: Faculty of Science and Technology > Psychology
ID Code: 81708
Deposited By: ep_importer_pure
Deposited On: 23 Sep 2016 09:22
Refereed?: Yes
Published?: Published
Last Modified: 01 Jan 2020 09:57
URI: https://eprints.lancs.ac.uk/id/eprint/81708

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