Bidirectional isotachophoresis on a planar chip with integrated conductivity detection

Prest, J. E. and Baldock, S. J. and Fielden, P. R. and Goddard, N. J. and Brown, B. J. T. (2002) Bidirectional isotachophoresis on a planar chip with integrated conductivity detection. Analyst, 127 (11). pp. 1413-1419. ISSN 0003-2654

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Abstract

The use of a miniaturised planar separation device with integrated conductivity detection for performing bidirectional isotachophoresis (ITP) is described. The chips were produced in poly(methyl methacrylate) (PMMA) using a milling procedure. To enable bidirectional ITP the devices were designed to inject samples into the centre of the separation channel and incorporated two integrated on-column conductivity detectors, positioned at opposite ends of this channel. When used with a hydrodynamic sample transport system the devices were used for the analysis of a range of small ions: NH4+; Na+; Mg2+; Ca2+; Li+; NO3−; ClO4−; SO42−; F−. Results sucessfully achieved included the simultaneous separation of three anions and three cations.

Item Type:
Journal Article
Journal or Publication Title:
Analyst
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1300/1303
Subjects:
?? biochemistryspectroscopyenvironmental chemistryanalytical chemistryelectrochemistry ??
ID Code:
77554
Deposited By:
Deposited On:
07 Jan 2016 10:04
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 15:44