A versatile sample injection system for miniaturised isotachophoresis devices

Baldock, S. J. and Fielden, P. R. and Goddard, N. J. and Kretschmer, H. R. and Prest, J. E. and Brown, B. J. Treves (2008) A versatile sample injection system for miniaturised isotachophoresis devices. Microelectronic Engineering, 85 (5-6). pp. 1440-1442. ISSN 0167-9317

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A variable-volume sample injector design is presented and evaluated for performing sample introduction protocols for carrying out miniaturised isotachophoresis (ITP) separations. The microdevice design features a wide bore sample loop channel connected to a narrower bore separation channel via a short injection channel angled at 45°. An additional side arm channel located at the injection point enabled a range of injection strategies, using a gravity-fed system, to be implemented and assessed. A model analyte was used to demonstrate the versatility of the injector design for low and high sample loading regimes suitable for concentrated and dilute sample solutions, respectively.

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Journal Article
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Microelectronic Engineering
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23 Dec 2015 13:42
Last Modified:
22 Nov 2022 02:42