Elucidating the spatially varying relation between cervical cancer and socio-economic conditions in England

Cheng, Edith M. Y. and Atkinson, Peter M. and Shahani, Arjan K. (2011) Elucidating the spatially varying relation between cervical cancer and socio-economic conditions in England. International Journal of Health Geographics, 10. pp. 51-67. ISSN 1476-072X

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Abstract

Background Geographically weighted Poisson regression (GWPR) was applied to the relation between cervical cancer disease incidence rates in England and socio-economic deprivation, social status and family structure covariates. Local parameters were estimated which describe the spatial variation in the relations between incidence and socio-economic covariates. Results A global (stationary) regression model revealed a significant correlation between cervical cancer incidence rates and social status. However, a local (non-stationary) GWPR model provided a better fit with less spatial correlation (positive autocorrelation) in the residuals. Moreover, the GWPR model was able to represent local variation in the relations between cervical cancer incidence and socio-economic covariates across space, whereas the global model represented only the overall (or average) relation for the whole of England. The global model could lead to misinterpretation of the relations between cervical cancer incidence and socio-economic covariates locally. Conclusions Cervical cancer incidence was shown to have a non-stationary relationship with spatially varying covariates that are available through national datasets. As a result, it was shown that if low social status sectors of the population are to be targeted preferentially, this targeting should be done on a region-by-region basis such as to optimize health outcomes. While such a strategy may be difficult to implement in practice, the research does highlight the inequalities inherent in a uniform intervention approach.

Item Type:
Journal Article
Journal or Publication Title:
International Journal of Health Geographics
Additional Information:
© 2011 Cheng et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. M1 - 1
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1700
Subjects:
ID Code:
77109
Deposited By:
Deposited On:
15 Dec 2015 13:36
Refereed?:
Yes
Published?:
Published
Last Modified:
27 May 2020 04:15